Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105300 . T A CCDS1196.1:NM_000702.3:c.2192aTg>aAg_NP_000693.1:p.731M>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 MET A:732 A:732 3.0 0.016 E -108.7 130.5 3.0 0.016 0.0 MG
HOH
 8.461
9.255
 CG
CG
 MG
O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 MET A:727 A:727 1.0 0.005 E -70.2 128.0 1.0 0.005 0.0 ALF
MG
HOH
 8.948
8.221
7.457
 CG
CG
CB
 F4
MG
O
MET D:727 C:727 3.0 0.016 E -87.9 124.9 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 MET A:727 A:727 1.0 0.005 E -72.9 120.6 1.0 0.005 0.0 ALF
MG
HOH
 9.254
7.882
7.010
 CG
CG
CB
 F4
MG
O
MET D:727 C:727 2.0 0.011 E -96.9 112.4 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 MET A:732 A:727 2.0 0.011 E -69.4 136.2 2.0 0.011 0.0 MG
 8.719
 CG
 MG
MET D:732 C:727 2.0 0.011 E -69.8 133.9 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 MET A:732 A:727 4.0 0.022 E -107.8 122.8 4.0 0.022 0.0 MG
 8.530
 CG
 MG
MET D:732 C:727 2.0 0.011 E -108.0 122.5 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 MET A:732 A:727 2.0 0.011 E -105.8 131.6 2.0 0.011 0.0 MG
 8.622
 CG
 MG
MET D:732 C:727 1.0 0.005 E -106.8 132.7 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 MET A:732 A:727 3.0 0.016 E -111.4 122.4 3.0 0.016 0.0 MG
 8.365
 CG
 MG
MET D:732 C:727 3.0 0.016 E -111.0 122.4 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 MET A:732 A:727 1.0 0.005 E -89.3 134.8 1.0 0.005 0.0 MG
HOH
 7.167
8.313
 CG
CG
 MG
O
MET D:732 C:727 1.0 0.005 E -89.9 132.9 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -85.2 133.3 1.0 0.005 0.0 MG
HOH
 7.506
8.275
 CG
CG
 MG
O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -83.6 134.5 1.0 0.005 0.0 MG
HOH
 7.325
7.946
 CG
CG
 MG
O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -81.5 130.5 1.0 0.005 0.0 MG
HOH
 7.371
8.242
 CG
CG
 MG
O
MET C:727 C:727 1.0 0.005 E -82.7 129.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -80.3 129.5 1.0 0.005 0.0 MG
HOH
 7.402
8.186
 CG
CG
 MG
O
MET D:727 C:727 1.0 0.005 E -81.6 130.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -81.8 135.0 1.0 0.005 0.0 MG
HOH
 7.594
8.112
 CG
CG
 MG
O
MET D:727 C:727 1.0 0.005 E -76.8 131.3 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 0.0 0.0 E -74.0 139.0 0.0 0.0 0.0 MG
HOH
 6.979
7.824
 CG
CG
 MG
O
MET D:727 C:727 0.0 0.0 E -74.7 136.3 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -87.5 135.9 1.0 0.005 0.0 MG
HOH
 7.342
7.993
 CG
CG
 MG
O
MET D:727 C:727 0.0 0.0 E -86.4 135.2 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -79.3 131.0 1.0 0.005 0.0 MG
HOH
 7.335
8.272
 CG
CG
 MG
O
MET D:727 C:727 1.0 0.005 E -81.6 130.4 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 0.0 0.0 E -86.4 131.1 0.0 0.0 0.0 MG
HOH
 7.152
7.959
 CG
CG
 MG
O
MET D:727 C:727 1.0 0.005 E -82.9 130.7 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:727 A:727 1.0 0.005 E -80.7 129.2 1.0 0.005 0.0 MG
HOH
 7.306
7.961
 CG
CG
 MG
O
MET D:727 C:727 1.0 0.005 E -79.9 129.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 MET A:709 A:727 2.0 0.011 -159.8 28.1 2.0 0.011 0.0 MG
 8.222
 CG
 MG
MET D:709 C:727 2.0 0.011 -159.1 28.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 MET A:709 A:727 0.0 0.0 E -117.0 152.1 0.0 0.0 0.0 MF4
MG
 9.654
7.859
 CG
CG
 F2
MG
MET D:709 C:727 0.0 0.0 E -115.9 148.3 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 MET A:703 A:727 1.0 0.005 E -94.3 114.0 1.0 0.005 0.0 MG
 7.741
 CG
 MG
MET D:703 C:727 1.0 0.005 E -93.8 113.4 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
HOH
 8.969
7.186
4.927
 CG
CG
O
 F2
MG
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 MET A:739 A:734 2.0 0.011 E -83.9 133.2 2.0 0.011 0.0 MF4
MG
HOH
 8.967
7.181
6.747
 CG
CG
CE
 F2
MG
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.969
7.186
 CG
CG
 F2
MG
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.970
7.186
 CG
CG
 F2
MG
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.6 135.9 3.0 0.016 0.0 MF4
MG
 8.971
7.186
 CG
CG
 F2
MG
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.8 3.0 0.016 0.0 MF4
MG
 8.969
7.185
 CG
CG
 F2
MG
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.968
7.185
 CG
CG
 F2
MG
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.6 135.9 3.0 0.016 0.0 MF4
MG
 8.970
7.186
 CG
CG
 F2
MG
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.970
7.186
 CG
CG
 F2
MG
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.6 135.9 3.0 0.016 0.0 MF4
MG
 8.971
7.187
 CG
CG
 F2
MG
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.969
7.186
 CG
CG
 F2
MG
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.971
7.185
 CG
CG
 F2
MG
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.8 3.0 0.016 0.0 MF4
MG
 8.968
7.185
 CG
CG
 F2
MG
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.6 135.9 3.0 0.016 0.0 MF4
MG
 8.969
7.186
 CG
CG
 F2
MG
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.969
7.184
 CG
CG
 F2
MG
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.6 135.9 3.0 0.016 0.0 MF4
MG
 8.969
7.186
 CG
CG
 F2
MG
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.8 135.9 3.0 0.016 0.0 MF4
MG
 8.969
7.185
 CG
CG
 F2
MG
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.970
7.186
 CG
CG
 F2
MG
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 136.0 3.0 0.016 0.0 MF4
MG
 8.970
7.186
 CG
CG
 F2
MG
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.7 135.9 3.0 0.016 0.0 MF4
MG
 8.970
7.185
 CG
CG
 F2
MG
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.8 135.9 3.0 0.016 0.0 MF4
MG
 8.971
7.187
 CG
CG
 F2
MG
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:739 A:734 3.0 0.016 E -78.6 129.2 3.0 0.016 0.0 MF4
MG
HOH
 8.995
7.212
4.935
 CG
CG
O
 F2
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 MET A:731 A:731 1.0 0.005 E -72.4 135.9
af-p13637-f1 1 P13637 88.37 0.0 MET A:724 A:724 1.0 0.005 E -71.2 134.3
af-p05023-f1 1 P05023 86.71 0.0 MET A:734 A:734 2.0 0.011 E -72.5 133.9
af-q13733-f1 1 Q13733 80.48 0.0 MET A:740 A:740 1.0 0.005 E -72.3 138.0