Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160105318 | . | A | C | CCDS1196.1:NM_000702.3:c.2210gAc>gCc_NP_000693.1:p.737D>A | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | ASP | A:738 | A:738 | 97.0 | 0.647 | S | -80.4 | -42.1 | 97.0 | 0.647 | 0.0 | ||||||
3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:733 | A:733 | 38.0 | 0.253 | H | -55.3 | -57.7 | 38.0 | 0.253 | 0.0 | ||||||
ASP | D:733 | C:733 | 31.0 | 0.207 | H | -66.7 | -45.9 | NA | NA | NA | |||||||||||||
3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:733 | A:733 | 33.0 | 0.22 | H | -49.2 | -58.1 | 33.0 | 0.22 | 0.0 | ||||||
ASP | D:733 | C:733 | 33.0 | 0.22 | H | -65.5 | -47.0 | NA | NA | NA | |||||||||||||
4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | ASP | A:738 | A:733 | 24.0 | 0.16 | H | -71.1 | -37.6 | 24.0 | 0.16 | 0.0 | ||||||
ASP | D:738 | C:733 | 23.0 | 0.153 | H | -70.3 | -38.9 | NA | NA | NA | |||||||||||||
4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | ASP | A:738 | A:733 | 84.0 | 0.56 | H | -79.0 | -41.6 | 84.0 | 0.56 | 0.0 | ||||||
ASP | D:738 | C:733 | 80.0 | 0.533 | H | -79.0 | -40.9 | NA | NA | NA | |||||||||||||
4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:738 | A:733 | 70.0 | 0.467 | S | -80.4 | -40.7 | 70.0 | 0.467 | 0.0 | ||||||
ASP | D:738 | C:733 | 65.0 | 0.433 | S | -80.4 | -41.4 | NA | NA | NA | |||||||||||||
4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:738 | A:733 | 81.0 | 0.54 | H | -78.6 | -43.0 | 81.0 | 0.54 | 0.0 | ||||||
ASP | D:738 | C:733 | 78.0 | 0.52 | H | -78.7 | -42.4 | NA | NA | NA | |||||||||||||
7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | ASP | A:738 | A:733 | 72.0 | 0.48 | H | -67.3 | -33.0 | 72.0 | 0.48 | 0.0 |
HOH |
9.780 |
N |
O |
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ASP | D:738 | C:733 | 68.0 | 0.453 | H | -66.5 | -31.4 | NA | NA | NA | |||||||||||||
7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 47.0 | 0.313 | H | -71.8 | -37.2 | 47.0 | 0.313 | 0.0 | ||||||
7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 49.0 | 0.327 | H | -67.7 | -36.7 | 49.0 | 0.327 | 0.0 | ||||||
7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 69.0 | 0.46 | H | -65.7 | -36.5 | 69.0 | 0.46 | 0.0 |
HOH |
9.949 |
N |
O |
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ASP | C:733 | C:733 | 69.0 | 0.46 | H | -65.6 | -35.7 | NA | NA | NA | |||||||||||||
7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 68.0 | 0.453 | H | -64.6 | -36.8 | 68.0 | 0.453 | 0.0 |
HOH |
9.824 |
N |
O |
||
ASP | D:733 | C:733 | 71.0 | 0.473 | H | -64.2 | -36.6 | NA | NA | NA | |||||||||||||
7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 88.0 | 0.587 | H | -73.4 | -30.6 | 88.0 | 0.587 | 0.0 | ||||||
ASP | D:733 | C:733 | 85.0 | 0.567 | H | -73.5 | -32.2 | NA | NA | NA | |||||||||||||
7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 74.0 | 0.493 | H | -84.4 | -31.4 | 74.0 | 0.493 | 0.0 | ||||||
ASP | D:733 | C:733 | 72.0 | 0.48 | H | -84.4 | -32.8 | NA | NA | NA | |||||||||||||
7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 75.0 | 0.5 | H | -66.6 | -35.7 | 75.0 | 0.5 | 0.0 |
HOH |
9.440 |
N |
O |
||
ASP | D:733 | C:733 | 70.0 | 0.467 | H | -66.4 | -34.9 | NA | NA | NA | |||||||||||||
7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 69.0 | 0.46 | H | -64.9 | -36.6 | 69.0 | 0.46 | 0.0 | ||||||
ASP | D:733 | C:733 | 72.0 | 0.48 | H | -64.9 | -37.2 | NA | NA | NA | |||||||||||||
7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 76.0 | 0.507 | H | -65.0 | -34.4 | 76.0 | 0.507 | 0.0 |
HOH |
9.914 |
N |
O |
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ASP | D:733 | C:733 | 72.0 | 0.48 | H | -64.3 | -33.0 | NA | NA | NA | |||||||||||||
7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:733 | A:733 | 70.0 | 0.467 | H | -65.3 | -35.6 | 70.0 | 0.467 | 0.0 |
HOH |
9.622 |
N |
O |
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ASP | D:733 | C:733 | 71.0 | 0.473 | H | -63.8 | -35.0 | NA | NA | NA | |||||||||||||
3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | ASP | A:715 | A:733 | 124.0 | 0.827 | T | -62.0 | 26.1 | 124.0 | 0.827 | 0.0 | ||||||
ASP | D:715 | C:733 | 123.0 | 0.82 | T | -61.7 | 26.2 | NA | NA | NA | |||||||||||||
3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | ASP | A:715 | A:733 | 107.0 | 0.713 | H | -29.3 | -51.8 | 107.0 | 0.713 | 0.0 | ||||||
ASP | D:715 | C:733 | 111.0 | 0.74 | H | -27.8 | -53.0 | NA | NA | NA | |||||||||||||
3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ASP | A:709 | A:733 | 96.0 | 0.64 | H | -58.3 | -64.9 | 96.0 | 0.64 | 0.0 | ||||||
ASP | D:709 | C:733 | 66.0 | 0.44 | H | -58.2 | -65.0 | NA | NA | NA | |||||||||||||
2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ASP | A:745 | A:740 | 81.0 | 0.54 | H | -52.1 | -46.5 | 81.0 | 0.54 | 0.0 |
HOH |
3.516 |
N |
O |
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3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ASP | A:745 | A:740 | 75.0 | 0.5 | H | -68.6 | -31.0 | 75.0 | 0.5 | 0.0 |
HOH |
9.871 |
O |
O |
||
5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.2 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.0 | -46.6 | 82.0 | 0.547 | 0.0 | ||||||
5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.0 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.6 | 82.0 | 0.547 | 0.0 | ||||||
5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.0 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.0 | -46.6 | 82.0 | 0.547 | 0.0 | ||||||
5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.6 | 82.0 | 0.547 | 0.0 | ||||||
5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.6 | 82.0 | 0.547 | 0.0 | ||||||
5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 81.0 | 0.54 | H | -52.2 | -46.4 | 81.0 | 0.54 | 0.0 | ||||||
5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.2 | -46.4 | 82.0 | 0.547 | 0.0 | ||||||
5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 82.0 | 0.547 | H | -52.1 | -46.5 | 82.0 | 0.547 | 0.0 | ||||||
5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:745 | A:740 | 80.0 | 0.533 | H | -56.7 | -41.0 | 80.0 | 0.533 | 0.0 |
HOH |
3.535 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ASP | A:737 | A:737 | 103.0 | 0.687 | H | -60.9 | -31.1 | |
af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | ASP | A:730 | A:730 | 46.0 | 0.307 | H | -66.7 | -34.2 | |
af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | ASP | A:740 | A:740 | 57.0 | 0.38 | H | -65.2 | -30.1 | |
af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ASP | A:746 | A:746 | 94.0 | 0.627 | H | -60.8 | -25.1 |