Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105320 . G A CCDS1196.1:NM_000702.3:c.2212Gtc>Atc_NP_000693.1:p.738V>I Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 VAL A:739 A:739 13.0 0.084 H -61.0 -51.1 13.0 0.084 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 VAL A:734 A:734 23.0 0.148 H -65.3 -29.2 23.0 0.148 0.0
VAL D:734 C:734 17.0 0.11 H -58.4 -48.1 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 VAL A:734 A:734 20.0 0.129 H -58.2 -43.9 20.0 0.129 0.0
VAL D:734 C:734 17.0 0.11 H -59.2 -47.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 VAL A:739 A:734 17.0 0.11 H -65.5 -49.8 17.0 0.11 0.0
VAL D:739 C:734 16.0 0.103 H -64.7 -49.5 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 VAL A:739 A:734 23.0 0.148 H -64.6 -42.7 23.0 0.148 0.0
VAL D:739 C:734 21.0 0.135 H -65.4 -42.4 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 VAL A:739 A:734 18.0 0.116 H -70.3 -29.1 18.0 0.116 0.0 K
 9.502
 O
 K
VAL D:739 C:734 18.0 0.116 H -69.5 -29.4 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 VAL A:739 A:734 24.0 0.155 H -64.2 -47.0 24.0 0.155 0.0
VAL D:739 C:734 16.0 0.103 H -64.8 -47.2 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 VAL A:739 A:734 31.0 0.2 H -64.7 -55.9 31.0 0.2 0.0
VAL D:739 C:734 35.0 0.226 H -64.3 -57.8 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 34.0 0.219 H -60.3 -55.8 34.0 0.219 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 32.0 0.206 H -60.3 -57.5 32.0 0.206 0.0 HOH
 9.844
 O
 O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 30.0 0.194 H -66.8 -49.0 30.0 0.194 0.0
VAL C:734 C:734 34.0 0.219 H -66.0 -49.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 31.0 0.2 H -66.2 -49.6 31.0 0.2 0.0
VAL D:734 C:734 34.0 0.219 H -65.5 -50.6 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 30.0 0.194 H -63.1 -55.2 30.0 0.194 0.0
VAL D:734 C:734 37.0 0.239 H -64.2 -55.9 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 28.0 0.181 H -63.5 -57.2 28.0 0.181 0.0
VAL D:734 C:734 38.0 0.245 H -63.9 -56.2 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 31.0 0.2 H -62.5 -56.1 31.0 0.2 0.0
VAL D:734 C:734 38.0 0.245 H -62.8 -56.0 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 31.0 0.2 H -67.6 -48.1 31.0 0.2 0.0
VAL D:734 C:734 36.0 0.232 H -67.1 -48.0 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 29.0 0.187 H -63.3 -58.0 29.0 0.187 0.0
VAL D:734 C:734 36.0 0.232 H -62.8 -58.6 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:734 A:734 30.0 0.194 H -65.5 -52.0 30.0 0.194 0.0
VAL D:734 C:734 33.0 0.213 H -65.3 -51.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 VAL A:716 A:734 2.0 0.013 T -138.0 -51.8 2.0 0.013 0.0
VAL D:716 C:734 4.0 0.026 T -138.2 -52.2 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 VAL A:716 A:734 3.0 0.019 H -60.8 -84.7 3.0 0.019 0.0
VAL D:716 C:734 3.0 0.019 H -60.4 -85.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 VAL A:710 A:734 30.0 0.194 H -58.1 -26.1 30.0 0.194 0.0
VAL D:710 C:734 29.0 0.187 H -58.1 -25.4 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0 HOH
 3.551
 CG2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 VAL A:746 A:741 3.0 0.019 H -66.7 -49.1 3.0 0.019 0.0 HOH
 7.979
 O
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.9 4.0 0.026 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.8 4.0 0.026 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.9 4.0 0.026 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.9 4.0 0.026 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.9 4.0 0.026 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.9 4.0 0.026 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.8 4.0 0.026 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.2 -51.9 4.0 0.026 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.8 4.0 0.026 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.8 4.0 0.026 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.4 -51.8 4.0 0.026 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.7 4.0 0.026 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -55.3 -51.9 4.0 0.026 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:746 A:741 4.0 0.026 H -56.6 -51.0 4.0 0.026 0.0 HOH
 3.601
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 VAL A:738 A:738 0.0 0.0 H -66.2 -48.8
af-p13637-f1 1 P13637 88.37 0.0 VAL A:731 A:731 55.0 0.355 H -61.4 -40.6
af-p05023-f1 1 P05023 86.71 0.0 VAL A:741 A:741 55.0 0.355 H -68.4 -41.9
af-q13733-f1 1 Q13733 80.48 0.0 VAL A:747 A:747 0.0 0.0 H -72.5 -48.0