Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160105635 | . | T | A | CCDS1196.1:NM_000702.3:c.2291cTg>cAg_NP_000693.1:p.764L>Q | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | LEU | A:765 | A:765 | 19.0 | 0.112 | H | -79.2 | -49.4 | 19.0 | 0.112 | 0.0 | ||||||
3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | LEU | A:760 | A:760 | 12.0 | 0.071 | H | -72.1 | -41.4 | 12.0 | 0.071 | 0.0 |
HOH |
8.239 |
CD2 |
O |
||
LEU | D:760 | C:760 | 12.0 | 0.071 | H | -68.4 | -48.5 | NA | NA | NA | |||||||||||||
3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | LEU | A:760 | A:760 | 15.0 | 0.088 | H | -72.6 | -43.8 | 15.0 | 0.088 | 0.0 |
HOH |
8.182 |
CD2 |
O |
||
LEU | D:760 | C:760 | 13.0 | 0.076 | H | -74.9 | -39.6 | NA | NA | NA | |||||||||||||
4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | LEU | A:765 | A:760 | 10.0 | 0.059 | H | -53.2 | -48.5 | 10.0 | 0.059 | 0.0 | ||||||
LEU | D:765 | C:760 | 10.0 | 0.059 | H | -52.8 | -48.1 | NA | NA | NA | |||||||||||||
4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | LEU | A:765 | A:760 | 15.0 | 0.088 | H | -76.3 | -47.2 | 15.0 | 0.088 | 0.0 | ||||||
LEU | D:765 | C:760 | 13.0 | 0.076 | H | -75.9 | -48.0 | NA | NA | NA | |||||||||||||
4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | LEU | A:765 | A:760 | 27.0 | 0.159 | H | -71.3 | -57.8 | 27.0 | 0.159 | 0.0 | ||||||
LEU | D:765 | C:760 | 27.0 | 0.159 | H | -71.5 | -57.8 | NA | NA | NA | |||||||||||||
4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | LEU | A:765 | A:760 | 18.0 | 0.106 | H | -77.0 | -50.6 | 18.0 | 0.106 | 0.0 | ||||||
LEU | D:765 | C:760 | 20.0 | 0.118 | H | -76.7 | -50.7 | NA | NA | NA | |||||||||||||
7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | LEU | A:765 | A:760 | 22.0 | 0.129 | H | -62.0 | -53.1 | 22.0 | 0.129 | 0.0 | ||||||
LEU | D:765 | C:760 | 21.0 | 0.124 | H | -62.2 | -53.1 | NA | NA | NA | |||||||||||||
7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 6.0 | 0.035 | H | -62.6 | -46.4 | 6.0 | 0.035 | 0.0 | ||||||
7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 6.0 | 0.035 | H | -61.5 | -47.5 | 6.0 | 0.035 | 0.0 | ||||||
7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 23.0 | 0.135 | H | -59.4 | -56.5 | 23.0 | 0.135 | 0.0 | ||||||
LEU | C:760 | C:760 | 19.0 | 0.112 | H | -59.5 | -54.0 | NA | NA | NA | |||||||||||||
7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 22.0 | 0.129 | H | -59.3 | -57.0 | 22.0 | 0.129 | 0.0 | ||||||
LEU | D:760 | C:760 | 20.0 | 0.118 | H | -59.7 | -55.5 | NA | NA | NA | |||||||||||||
7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 22.0 | 0.129 | H | -66.0 | -46.2 | 22.0 | 0.129 | 0.0 | ||||||
LEU | D:760 | C:760 | 22.0 | 0.129 | H | -70.0 | -49.6 | NA | NA | NA | |||||||||||||
7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 22.0 | 0.129 | H | -58.9 | -57.0 | 22.0 | 0.129 | 0.0 | ||||||
LEU | D:760 | C:760 | 20.0 | 0.118 | H | -59.4 | -55.3 | NA | NA | NA | |||||||||||||
7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 22.0 | 0.129 | H | -51.1 | -63.5 | 22.0 | 0.129 | 0.0 | ||||||
LEU | D:760 | C:760 | 19.0 | 0.112 | H | -50.9 | -63.8 | NA | NA | NA | |||||||||||||
7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 23.0 | 0.135 | H | -59.4 | -56.1 | 23.0 | 0.135 | 0.0 | ||||||
LEU | D:760 | C:760 | 19.0 | 0.112 | H | -60.1 | -53.4 | NA | NA | NA | |||||||||||||
7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 22.0 | 0.129 | H | -59.0 | -55.4 | 22.0 | 0.129 | 0.0 | ||||||
LEU | D:760 | C:760 | 22.0 | 0.129 | H | -58.7 | -54.8 | NA | NA | NA | |||||||||||||
7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | LEU | A:760 | A:760 | 21.0 | 0.124 | H | -58.2 | -57.9 | 21.0 | 0.124 | 0.0 | ||||||
LEU | D:760 | C:760 | 20.0 | 0.118 | H | -58.8 | -55.5 | NA | NA | NA | |||||||||||||
3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | LEU | A:742 | A:760 | 17.0 | 0.1 | H | -59.5 | -59.0 | 17.0 | 0.1 | 0.0 | ||||||
LEU | D:742 | C:760 | 11.0 | 0.065 | H | -59.3 | -59.3 | NA | NA | NA | |||||||||||||
3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | LEU | A:742 | A:760 | 17.0 | 0.1 | H | -87.8 | -42.1 | 17.0 | 0.1 | 0.0 | ||||||
LEU | D:742 | C:760 | 14.0 | 0.082 | H | -87.5 | -43.4 | NA | NA | NA | |||||||||||||
3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | LEU | A:736 | A:760 | 29.0 | 0.171 | H | -67.6 | -50.0 | 29.0 | 0.171 | 0.0 | ||||||
LEU | D:736 | C:760 | 28.0 | 0.165 | H | -67.3 | -50.2 | NA | NA | NA | |||||||||||||
2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 |
HOH |
3.356 |
CD1 |
O |
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3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -51.8 | -55.2 | 20.0 | 0.118 | 0.0 |
HOH |
3.978 |
CD2 |
O |
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5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.4 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.4 | -44.2 | 20.0 | 0.118 | 0.0 | ||||||
5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.4 | -44.2 | 20.0 | 0.118 | 0.0 | ||||||
5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.2 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.2 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.4 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.2 | -44.3 | 20.0 | 0.118 | 0.0 | ||||||
5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.3 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 20.0 | 0.118 | H | -60.2 | -44.4 | 20.0 | 0.118 | 0.0 | ||||||
5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:772 | A:767 | 17.0 | 0.1 | H | -58.0 | -49.1 | 17.0 | 0.1 | 0.0 |
HOH |
3.445 |
CD1 |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | LEU | A:764 | A:764 | 17.0 | 0.1 | H | -66.1 | -47.4 | |
af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | LEU | A:757 | A:757 | 17.0 | 0.1 | H | -66.1 | -47.9 | |
af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | LEU | A:767 | A:767 | 18.0 | 0.106 | H | -66.3 | -47.5 | |
af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | LEU | A:773 | A:773 | 16.0 | 0.094 | H | -64.9 | -47.3 |