Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105725 . A C CCDS1196.1:NM_000702.3:c.2381aAc>aCc_NP_000693.1:p.794N>T Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ASN A:795 A:795 22.0 0.138 54.3 40.1 22.0 0.138 0.0 OBN
 7.242
 OD1
 C6'
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ASN A:790 A:790 65.0 0.406 45.8 52.1 65.0 0.406 0.0
ASN D:790 C:790 60.0 0.375 57.2 54.9 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ASN A:790 A:790 67.0 0.419 46.4 52.5 67.0 0.419 0.0
ASN D:790 C:790 61.0 0.381 56.5 58.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ASN A:795 A:790 55.0 0.344 -68.5 64.2 55.0 0.344 0.0
ASN D:795 C:790 54.0 0.338 -67.6 65.1 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ASN A:795 A:790 19.0 0.119 54.9 44.2 19.0 0.119 0.0 OBN
 6.381
 OD1
 C6'
ASN D:795 C:790 21.0 0.131 55.2 44.3 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ASN A:795 A:790 20.0 0.125 55.6 41.6 20.0 0.125 0.0
ASN D:795 C:790 20.0 0.125 55.3 41.9 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ASN A:795 A:790 17.0 0.106 54.7 44.8 17.0 0.106 0.0 DGX
 6.748
 OD1
 O3X
ASN D:795 C:790 19.0 0.119 55.0 45.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ASN A:795 A:790 23.0 0.144 55.5 46.7 23.0 0.144 0.0 JEO
 9.160
 OD1
 NAZ
ASN D:795 C:790 20.0 0.125 55.5 48.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 21.0 0.131 58.4 53.0 21.0 0.131 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 19.0 0.119 58.2 52.4 19.0 0.119 0.0 H0C
 6.764
 OD1
 C44
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 23.0 0.144 55.1 48.0 23.0 0.144 0.0 H0C
 6.995
 OD1
 C44
ASN C:790 C:790 22.0 0.138 55.8 50.9 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 20.0 0.125 54.5 49.6 20.0 0.125 0.0
ASN D:790 C:790 18.0 0.113 55.4 52.9 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 27.0 0.169 55.7 53.2 27.0 0.169 0.0
ASN D:790 C:790 24.0 0.15 56.1 55.9 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 18.0 0.113 58.5 52.6 18.0 0.113 0.0 DGX
 8.130
 OD1
 O3X
ASN D:790 C:790 15.0 0.094 57.9 53.4 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 22.0 0.138 55.2 43.5 22.0 0.138 0.0 F9R
 8.145
 OD1
 O3X
ASN D:790 C:790 21.0 0.131 55.1 44.7 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 22.0 0.138 54.9 48.4 22.0 0.138 0.0 OBN
 7.074
 OD1
 C6'
ASN D:790 C:790 22.0 0.138 56.9 50.9 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 22.0 0.138 55.3 50.5 22.0 0.138 0.0 E4R
 9.950
 OD1
 C3
ASN D:790 C:790 22.0 0.138 56.0 52.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:790 A:790 22.0 0.138 55.5 49.5 22.0 0.138 0.0
ASN D:790 C:790 18.0 0.113 55.8 51.6 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ASN A:772 A:790 54.0 0.338 6.6 30.3 54.0 0.338 0.0
ASN D:772 C:790 58.0 0.362 20.2 60.7 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ASN A:772 A:790 40.0 0.25 1.7 53.4 40.0 0.25 0.0
ASN D:772 C:790 38.0 0.237 0.4 56.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ASN A:766 A:790 45.0 0.281 50.5 58.5 45.0 0.281 0.0 OBN
 6.935
 OD1
 C6'
ASN D:766 C:790 44.0 0.275 50.1 58.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ASN A:802 A:797 53.0 0.331 54.8 41.7 53.0 0.331 0.0 OBN
 6.838
 OD1
 C6'
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.6 39.9 50.0 0.312 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.6 39.9 50.0 0.312 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 39.9 50.0 0.312 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.6 39.9 50.0 0.312 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 39.9 50.0 0.312 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.4 40.0 50.0 0.312 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 39.8 50.0 0.312 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 39.9 50.0 0.312 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.6 40.0 50.0 0.312 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.6 39.9 50.0 0.312 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.7 39.9 50.0 0.312 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.5 40.0 50.0 0.312 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 50.0 0.312 57.6 39.9 50.0 0.312 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:802 A:797 51.0 0.319 53.6 36.5 51.0 0.319 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ASN A:794 A:794 39.0 0.244 49.1 47.2
af-p13637-f1 1 P13637 88.37 0.0 ASN A:787 A:787 43.0 0.269 50.0 45.0
af-p05023-f1 1 P05023 86.71 0.0 ASN A:797 A:797 38.0 0.237 48.5 46.7
af-q13733-f1 1 Q13733 80.48 0.0 GLY A:803 A:803 8.0 0.107 59.3 38.5