Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105731 . C A CCDS1196.1:NM_000702.3:c.2387cCc>cAc_NP_000693.1:p.796P>H Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 PRO A:797 A:797 1.0 0.007 -56.6 143.3 1.0 0.007 0.0 OBN
 8.774
 CA
 C6'
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 PRO A:792 A:792 0.0 0.0 -52.9 136.7 0.0 0.0 0.0
PRO D:792 C:792 1.0 0.007 -64.3 151.3 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 PRO A:792 A:792 0.0 0.0 -48.9 131.6 0.0 0.0 0.0
PRO D:792 C:792 1.0 0.007 -64.4 151.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 PRO A:797 A:792 1.0 0.007 -52.3 148.8 1.0 0.007 0.0
PRO D:797 C:792 1.0 0.007 -51.9 147.7 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 PRO A:797 A:792 3.0 0.021 -63.7 144.1 3.0 0.021 0.0 OBN
 8.660
 CA
 C6'
PRO D:797 C:792 2.0 0.014 -63.1 143.9 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 PRO A:797 A:792 2.0 0.014 -57.9 141.2 2.0 0.014 0.0 BUF
 9.219
 C
 C6
PRO D:797 C:792 2.0 0.014 -58.4 140.6 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 PRO A:797 A:792 1.0 0.007 -60.1 147.2 1.0 0.007 0.0 DGX
 8.698
 C
 C4
PRO D:797 C:792 1.0 0.007 -59.6 147.2 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 PRO A:797 A:792 2.0 0.014 -60.1 158.5 2.0 0.014 0.0 JEO
 9.872
 C
 CAC
PRO D:797 C:792 1.0 0.007 -60.1 158.3 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 2.0 0.014 -60.2 147.2 2.0 0.014 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 1.0 0.007 -58.6 147.4 1.0 0.007 0.0 H0C
 9.320
 C
 O13
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 1.0 0.007 -62.6 152.3 1.0 0.007 0.0 H0C
 9.043
 C
 C31
PRO C:792 C:792 1.0 0.007 -62.5 150.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 1.0 0.007 -63.1 152.8 1.0 0.007 0.0 BUF
 9.021
 C
 C4
PRO D:792 C:792 2.0 0.014 -63.5 150.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 2.0 0.014 -63.0 160.9 2.0 0.014 0.0
PRO D:792 C:792 2.0 0.014 -62.7 161.5 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 1.0 0.007 -61.8 151.0 1.0 0.007 0.0 DGX
 8.894
 C
 C4
PRO D:792 C:792 1.0 0.007 -61.5 151.0 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 2.0 0.014 -58.5 156.0 2.0 0.014 0.0 F9R
 8.942
 C
 C4
PRO D:792 C:792 3.0 0.021 -59.2 155.9 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 1.0 0.007 -63.0 152.7 1.0 0.007 0.0 OBN
 8.735
 C
 C4
PRO D:792 C:792 1.0 0.007 -63.9 149.0 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 2.0 0.014 -59.8 154.7 2.0 0.014 0.0 E4R
 8.397
 C
 C4
PRO D:792 C:792 1.0 0.007 -60.4 154.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:792 A:792 1.0 0.007 -62.7 151.2 1.0 0.007 0.0 BUF
 8.818
 C
 C4
PRO D:792 C:792 1.0 0.007 -62.5 150.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 PRO A:774 A:792 6.0 0.041 -9.4 126.5 6.0 0.041 0.0
PRO D:774 C:792 4.0 0.028 -79.6 129.0 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 PRO A:774 A:792 2.0 0.014 -69.5 119.0 2.0 0.014 0.0
PRO D:774 C:792 2.0 0.014 -71.0 119.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 PRO A:768 A:792 2.0 0.014 -55.2 159.4 2.0 0.014 0.0 OBN
 8.803
 C
 O5'
PRO D:768 C:792 2.0 0.014 -53.4 159.0 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0 HOH
 8.200
 CD
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 PRO A:804 A:799 0.0 0.0 -68.0 142.5 0.0 0.0 0.0 OBN
 8.893
 C
 C4
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.3 142.1 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.1 142.1 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.1 142.1 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.1 142.1 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.0 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.1 142.1 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.3 142.1 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.1 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.1 142.1 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.2 142.0 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -64.1 142.0 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:804 A:799 0.0 0.0 -63.6 146.4 0.0 0.0 0.0 HOH
 8.274
 CD
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 PRO A:796 A:796 1.0 0.007 -55.2 151.1
af-p13637-f1 1 P13637 88.37 0.0 PRO A:789 A:789 1.0 0.007 -55.5 151.5
af-p05023-f1 1 P05023 86.71 0.0 PRO A:799 A:799 2.0 0.014 -52.4 149.1
af-q13733-f1 1 Q13733 80.48 0.0 PRO A:805 A:805 2.0 0.014 -55.9 151.5