Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160106360 . G A CCDS1196.1:NM_000702.3:c.2564gGg>gAg_NP_000693.1:p.855G>E Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 GLY A:856 A:856 0.0 0.0 H -56.5 -32.8 0.0 0.0 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLY A:851 A:851 0.0 0.0 H -74.1 -29.9 0.0 0.0 0.0 NA
NA
PC1
CLR
 9.674
8.073
9.915
8.184
 CA
CA
C
C
 NA
NA
C3B
C16
GLY D:851 C:851 0.0 0.0 H -67.7 -23.2 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLY A:851 A:851 0.0 0.0 H -66.8 -32.4 0.0 0.0 0.0 NA
NA
CLR
PC1
 9.751
8.280
8.072
9.867
 CA
CA
C
C
 NA
NA
C16
C3B
GLY D:851 C:851 0.0 0.0 H -64.7 -34.9 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 GLY A:856 A:851 0.0 0.0 I -43.2 -45.9 0.0 0.0 0.0 NA
 6.132
 CA
 NA
GLY D:856 C:851 0.0 0.0 I -44.3 -45.1 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 GLY A:856 A:851 0.0 0.0 H -53.8 -37.7 0.0 0.0 0.0 17F
 9.694
 C
 C20
GLY D:856 C:851 0.0 0.0 H -54.4 -37.5 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLY A:856 A:851 0.0 0.0 H -48.6 -38.9 0.0 0.0 0.0
GLY D:856 C:851 0.0 0.0 H -48.4 -38.7 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLY A:856 A:851 0.0 0.0 H -59.1 -31.3 0.0 0.0 0.0 17F
 8.648
 C
 C31
GLY D:856 C:851 0.0 0.0 H -59.2 -31.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 GLY A:856 A:851 0.0 0.0 H -61.3 -28.2 0.0 0.0 0.0
GLY D:856 C:851 0.0 0.0 H -61.5 -27.4 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -55.8 -34.6 0.0 0.0 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -56.3 -34.5 0.0 0.0 0.0 CLR
 8.526
 C
 C23
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -58.2 -30.8 0.0 0.0 0.0
GLY C:851 C:851 0.0 0.0 H -58.0 -30.5 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -58.0 -30.5 0.0 0.0 0.0 RB
 9.829
 CA
 RB
GLY D:851 C:851 0.0 0.0 H -58.6 -30.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -58.0 -27.2 0.0 0.0 0.0 CLR
 9.730
 C
 C18
GLY D:851 C:851 0.0 0.0 H -58.3 -27.8 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -56.2 -28.8 0.0 0.0 0.0 CLR
 9.919
 C
 C18
GLY D:851 C:851 0.0 0.0 H -55.9 -29.8 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -56.9 -28.9 0.0 0.0 0.0
GLY D:851 C:851 0.0 0.0 H -57.6 -28.9 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -58.3 -30.5 0.0 0.0 0.0
GLY D:851 C:851 0.0 0.0 H -58.6 -31.1 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -58.3 -28.7 0.0 0.0 0.0 CLR
 9.895
 C
 C15
GLY D:851 C:851 0.0 0.0 H -58.1 -28.9 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:851 A:851 0.0 0.0 H -57.4 -30.9 0.0 0.0 0.0
GLY D:851 C:851 0.0 0.0 H -57.0 -30.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 GLY A:833 A:851 0.0 0.0 H -45.8 -31.2 0.0 0.0 0.0 RB
PC1
 9.585
9.060
 CA
C
 RB
O12
GLY D:833 C:851 0.0 0.0 H -85.9 -18.4 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 GLY A:833 A:851 0.0 0.0 H -72.6 -45.0 0.0 0.0 0.0 RB
CLR
 9.971
9.186
 CA
CA
 RB
C15
GLY D:833 C:851 0.0 0.0 H -71.2 -45.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLY A:827 A:851 0.0 0.0 H -52.5 -37.0 0.0 0.0 0.0
GLY D:827 C:851 0.0 0.0 H -52.2 -37.8 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
CLR
 9.694
8.939
 CA
C
 K
C16
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 GLY A:863 A:858 0.0 0.0 I -55.8 -27.4 0.0 0.0 0.0 K
CLR
 9.799
8.796
 CA
O
 K
C24
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
TL
CLR
 9.693
9.693
8.939
 CA
CA
C
 K
TL
C16
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
TL
CLR
 9.693
9.693
8.940
 CA
CA
C
 K
TL
C16
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
TL
CLR
 9.693
9.693
8.939
 CA
CA
C
 K
TL
C16
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.3 -31.9 0.0 0.0 0.0 K
TL
CLR
 9.693
9.693
8.939
 CA
CA
C
 K
TL
C16
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
TL
CLR
 9.693
9.693
8.940
 CA
CA
C
 K
TL
C16
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 TL
CLR
 9.695
8.940
 CA
C
 TL
C16
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.3 -31.8 0.0 0.0 0.0 TL
CLR
 9.694
8.940
 CA
C
 TL
C16
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 TL
CLR
 9.693
8.939
 CA
C
 TL
C16
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 TL
CLR
 9.693
8.940
 CA
C
 TL
C16
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 TL
CLR
 9.694
8.940
 CA
C
 TL
C16
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.1 -31.9 0.0 0.0 0.0 TL
CLR
 9.694
8.941
 CA
C
 TL
C16
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
TL
CLR
 9.694
9.694
8.940
 CA
CA
C
 K
TL
C16
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.1 -32.0 0.0 0.0 0.0 TL
CLR
 9.694
8.940
 CA
C
 TL
C16
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.8 0.0 0.0 0.0 TL
CLR
 9.694
8.939
 CA
C
 TL
C16
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
RB
CLR
 9.695
9.695
8.940
 CA
CA
C
 K
RB
C16
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
RB
CLR
 9.695
9.695
8.940
 CA
CA
C
 K
RB
C16
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -32.0 0.0 0.0 0.0 K
RB
CLR
 9.694
9.694
8.940
 CA
CA
C
 K
RB
C16
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.9 0.0 0.0 0.0 K
RB
CLR
 9.693
9.693
8.940
 CA
CA
C
 K
RB
C16
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.2 -31.8 0.0 0.0 0.0 RB
CLR
 9.695
8.940
 CA
C
 RB
C16
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:863 A:858 0.0 0.0 H -60.4 -32.1 0.0 0.0 0.0 K
CLR
 9.676
9.078
 CA
O
 K
C26

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLY A:855 A:855 0.0 0.0 H -59.5 -31.2
af-p13637-f1 1 P13637 88.37 0.0 GLY A:848 A:848 0.0 0.0 H -59.0 -31.1
af-p05023-f1 1 P05023 86.71 0.0 GLY A:858 A:858 0.0 0.0 H -59.4 -30.7
af-q13733-f1 1 Q13733 80.48 0.0 GLY A:864 A:864 0.0 0.0 H -60.0 -31.0