Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160106416 . G A CCDS1196.1:NM_000702.3:c.2620Ggt>Agt_NP_000693.1:p.874G>S Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 GLY A:875 A:875 4.0 0.053 T 110.6 -8.6 0.0 0.0 0.053 B:G3MWR4:0.053
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLY A:870 A:870 1.0 0.013 T 124.5 -12.3 0.0 0.0 0.013 B:P05027:0.013
GLY D:870 C:870 4.0 0.053 T 118.3 -7.3 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLY A:870 A:870 1.0 0.013 T 130.8 -12.2 0.0 0.0 0.013 B:P05027:0.013
GLY D:870 C:870 2.0 0.027 T 139.7 -10.3 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 GLY A:875 A:870 6.0 0.08 T 97.4 -13.4 0.0 0.0 0.08 B:P05027:0.08
GLY D:875 C:870 5.0 0.067 T 97.6 -14.5 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 GLY A:875 A:870 2.0 0.027 T 112.6 -6.8 0.0 0.0 0.027 B:P05027:0.027
GLY D:875 C:870 3.0 0.04 T 112.7 -6.9 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLY A:875 A:870 4.0 0.053 T 111.6 -12.6 0.0 0.0 0.053 B:P05027:0.053
GLY D:875 C:870 3.0 0.04 T 110.8 -11.8 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLY A:875 A:870 3.0 0.04 T 110.0 -8.2 0.0 0.0 0.04 B:P05027:0.04
GLY D:875 C:870 4.0 0.053 T 110.0 -8.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 GLY A:875 A:870 2.0 0.027 T 110.2 1.1 0.0 0.0 0.027 B:P05027:0.027
GLY D:875 C:870 4.0 0.053 T 108.0 0.3 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 2.0 0.027 T 112.3 -17.4 0.0 0.0 0.027 B:P05027:0.027
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 2.0 0.027 T 113.1 -14.5 0.0 0.0 0.027 B:P05027:0.027
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 3.0 0.04 T 114.3 -10.3 0.0 0.0 0.04 B:P05027:0.04
GLY C:870 C:870 4.0 0.053 T 112.3 -8.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 4.0 0.053 T 113.6 -10.0 0.0 0.0 0.053 B:P05027:0.053
GLY D:870 C:870 5.0 0.067 T 112.7 -7.8 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 2.0 0.027 T 128.0 -8.5 0.0 0.0 0.027 B:P05027:0.027
GLY D:870 C:870 3.0 0.04 T 126.9 -7.6 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 2.0 0.027 T 114.2 -9.0 0.0 0.0 0.027 B:P05027:0.027
GLY D:870 C:870 2.0 0.027 T 113.6 -7.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 4.0 0.053 T 109.9 -2.0 0.0 0.0 0.053 B:P05027:0.053
GLY D:870 C:870 5.0 0.067 T 108.3 -1.3 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 4.0 0.053 T 114.4 -11.7 0.0 0.0 0.053 B:P05027:0.053
GLY D:870 C:870 5.0 0.067 T 112.4 -9.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 3.0 0.04 T 114.9 -6.6 0.0 0.0 0.04 B:P05027:0.04
GLY D:870 C:870 5.0 0.067 T 113.9 -5.2 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLY A:870 A:870 3.0 0.04 T 113.8 -8.7 0.0 0.0 0.04 B:P05027:0.04
GLY D:870 C:870 6.0 0.08 T 112.5 -7.1 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 GLY A:852 A:870 19.0 0.253 H 170.8 51.5 11.0 0.147 0.106 B:P05027:0.107
GLY D:852 C:870 19.0 0.253 T 121.3 43.2 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 GLY A:852 A:870 3.0 0.04 S 124.2 -76.6 0.0 0.0 0.04 B:P05027:0.04
GLY D:852 C:870 4.0 0.053 S 122.4 -74.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLY A:846 A:870 3.0 0.04 T 98.6 22.4 0.0 0.0 0.04 B:P05027:0.04
GLY D:846 C:870 3.0 0.04 T 99.3 22.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 GLY A:882 A:877 4.0 0.053 T 116.8 -9.9 0.0 0.0 0.053 B:None:0.053
 HOH
 6.634
 C
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 GLY A:882 A:877 5.0 0.067 T 105.9 5.6 0.0 0.0 0.067 B:None:0.067
 HOH
 9.862
 N
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.8 -9.8 0.0 0.0 0.053 B:C4IX13:0.053
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.9 -9.9 0.0 0.0 0.053 B:C4IX13:0.053
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.8 -10.0 0.0 0.0 0.053 B:C4IX13:0.053
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.8 -9.8 0.0 0.0 0.053 B:C4IX13:0.053
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.7 -9.8 0.0 0.0 0.053 B:C4IX13:0.053
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -10.0 0.0 0.0 0.04 B:C4IX13:0.04
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.9 -10.0 0.0 0.0 0.053 B:C4IX13:0.053
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -9.9 0.0 0.0 0.04 B:C4IX13:0.04
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -9.8 0.0 0.0 0.04 B:C4IX13:0.04
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.8 -9.9 0.0 0.0 0.053 B:C4IX13:0.053
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -9.9 0.0 0.0 0.04 B:C4IX13:0.04
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -9.9 0.0 0.0 0.04 B:C4IX13:0.04
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -9.9 0.0 0.0 0.04 B:C4IX13:0.04
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.9 -10.0 0.0 0.0 0.04 B:C4IX13:0.04
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.7 -9.8 0.0 0.0 0.053 B:C4IX13:0.053
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -9.8 0.0 0.0 0.04 B:C4IX13:0.04
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.7 -9.9 0.0 0.0 0.053 B:C4IX13:0.053
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 116.8 -10.0 0.0 0.0 0.04 B:C4IX13:0.04
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 4.0 0.053 T 116.8 -10.0 0.0 0.0 0.053 B:C4IX13:0.053
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLY A:882 A:877 3.0 0.04 T 118.5 -12.8 0.0 0.0 0.04 B:C4IX13:0.04
 HOH
 6.555
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLY A:874 A:874 3.0 0.04 T 111.4 -9.4
af-p13637-f1 1 P13637 88.37 0.0 GLY A:867 A:867 2.0 0.027 T 111.2 -8.2
af-p05023-f1 1 P05023 86.71 0.0 GLY A:877 A:877 3.0 0.04 T 115.3 -10.5
af-q13733-f1 1 Q13733 80.48 0.0 GLY A:883 A:883 3.0 0.04 T 106.8 -6.0