Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160106455 . T A CCDS1196.1:NM_000702.3:c.2659Tgg>Agg_NP_000693.1:p.887W>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 TRP A:888 A:888 0.0 0.0 H -73.1 -47.0 0.0 0.0 0.0 OBN
 8.335
 C
 C6'
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 TRP A:883 A:883 1.0 0.004 H -66.4 -41.5 1.0 0.004 0.0 HOH
 8.418
 NE1
 O
TRP D:883 C:883 0.0 0.0 H -68.6 -33.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 TRP A:883 A:883 1.0 0.004 H -60.1 -45.8 1.0 0.004 0.0 HOH
 8.392
 NE1
 O
TRP D:883 C:883 0.0 0.0 H -71.5 -36.3 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 TRP A:888 A:883 0.0 0.0 H -57.0 -61.5 0.0 0.0 0.0
TRP D:888 C:883 0.0 0.0 H -57.4 -60.2 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 TRP A:888 A:883 0.0 0.0 H -60.4 -48.1 0.0 0.0 0.0 OBN
 8.678
 C
 C6'
TRP D:888 C:883 0.0 0.0 H -60.4 -48.8 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 TRP A:888 A:883 1.0 0.004 H -74.6 -45.9 1.0 0.004 0.0
TRP D:888 C:883 1.0 0.004 H -74.4 -45.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 TRP A:888 A:883 0.0 0.0 H -68.5 -44.1 0.0 0.0 0.0 DGX
 9.614
 C
 C2X
TRP D:888 C:883 0.0 0.0 H -68.6 -44.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 TRP A:888 A:883 0.0 0.0 H -67.3 -50.7 0.0 0.0 0.0 JEO
 9.887
 C
 CAX
TRP D:888 C:883 0.0 0.0 H -66.9 -49.7 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -79.9 -40.4 0.0 0.0 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -77.4 -38.7 0.0 0.0 0.0 H0C
 7.387
 C
 O7
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -66.2 -48.0 0.0 0.0 0.0 H0C
 7.375
 C
 O7
TRP C:883 C:883 0.0 0.0 H -64.9 -47.0 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -66.1 -49.0 0.0 0.0 0.0
TRP D:883 C:883 0.0 0.0 H -64.9 -47.3 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 2.0 0.008 H -80.3 -54.2 2.0 0.008 0.0
TRP D:883 C:883 0.0 0.0 H -77.6 -53.6 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -66.9 -42.9 0.0 0.0 0.0 DGX
 8.753
 C
 O3X
TRP D:883 C:883 1.0 0.004 H -65.4 -43.7 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -82.0 -54.6 0.0 0.0 0.0 F9R
 7.929
 C
 C6Y
TRP D:883 C:883 1.0 0.004 H -81.7 -52.6 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -66.4 -48.0 0.0 0.0 0.0 OBN
 7.050
 C
 O2'
TRP D:883 C:883 0.0 0.0 H -63.5 -45.8 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 1.0 0.004 H -67.2 -47.4 1.0 0.004 0.0 E4R
 9.645
 C
 O3
TRP D:883 C:883 0.0 0.0 H -66.8 -46.5 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TRP A:883 A:883 0.0 0.0 H -64.0 -54.3 0.0 0.0 0.0
TRP D:883 C:883 0.0 0.0 H -64.5 -47.4 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 TRP A:865 A:883 241.0 0.945 S -86.5 -30.4 241.0 0.945 0.0
TRP D:865 C:883 237.0 0.929 T -73.1 -12.9 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 TRP A:865 A:883 4.0 0.016 H -43.0 -59.8 4.0 0.016 0.0
TRP D:865 C:883 5.0 0.02 H -42.1 -59.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 TRP A:859 A:883 1.0 0.004 H -50.5 -62.9 1.0 0.004 0.0 OBN
 7.885
 C
 O2'
TRP D:859 C:883 2.0 0.008 H -49.8 -63.9 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0 HOH
 8.760
 CZ3
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 TRP A:895 A:890 0.0 0.0 H -57.6 -48.5 0.0 0.0 0.0 OBN
 8.515
 C
 O2'
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.1 -44.1 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.1 -44.1 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.1 -44.0 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.1 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -65.0 -44.0 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 TRP A:895 A:890 0.0 0.0 H -63.2 -50.3 0.0 0.0 0.0 HOH
 8.811
 CZ3
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 TRP A:887 A:887 0.0 0.0 H -69.6 -35.6
af-p13637-f1 1 P13637 88.37 0.0 TRP A:880 A:880 0.0 0.0 H -72.8 -33.1
af-p05023-f1 1 P05023 86.71 0.0 TRP A:890 A:890 0.0 0.0 H -77.1 -19.3
af-q13733-f1 1 Q13733 80.48 0.0 TRP A:896 A:896 1.0 0.004 H -70.6 -29.5