Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160106722 . C A CCDS1196.1:NM_000702.3:c.2741aCg>aAg_NP_000693.1:p.914T>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:915 A:915 17.0 0.121 H -73.9 -24.1 3.0 0.021 0.1 B:G3MWR4:0.1
C:Q04645:0.036
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:910 A:910 18.0 0.129 H -71.7 -37.5 7.0 0.05 0.079 B:P05027:0.079
 HOH
 7.423
 N
 O
THR D:910 C:910 20.0 0.143 H -79.9 -5.7 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:910 A:910 20.0 0.143 H -73.8 -28.1 7.0 0.05 0.093 B:P05027:0.093
 HOH
 7.476
 N
 O
THR D:910 C:910 21.0 0.15 H -71.9 -12.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:915 A:910 15.0 0.107 H -85.1 1.7 2.0 0.014 0.093 B:P05027:0.093
THR D:915 C:910 16.0 0.114 H -85.2 2.6 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:915 A:910 18.0 0.129 T -82.1 -2.4 2.0 0.014 0.115 B:P05027:0.114
C:Q58K79:0.05
THR D:915 C:910 17.0 0.121 T -81.3 -2.3 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:915 A:910 22.0 0.157 T -85.9 3.0 6.0 0.043 0.114 B:P05027:0.107
C:Q58K79:0.029
THR D:915 C:910 21.0 0.15 T -86.4 3.3 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:915 A:910 17.0 0.121 T -85.7 0.4 3.0 0.021 0.1 B:P05027:0.1
C:Q58K79:0.021
THR D:915 C:910 18.0 0.129 T -86.0 0.1 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:915 A:910 24.0 0.171 H -80.4 6.7 8.0 0.057 0.114 B:P05027:0.114
C:Q58K79:0.05
THR D:915 C:910 26.0 0.186 H -79.3 5.9 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 16.0 0.114 H -77.7 2.7 2.0 0.014 0.1 B:P05027:0.1
C:Q58K79:0.029
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 19.0 0.136 H -76.4 0.8 3.0 0.021 0.115 B:P05027:0.107
C:Q58K79:0.036
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 22.0 0.157 H -76.3 3.3 7.0 0.05 0.107 B:P05027:0.1
F:Q58K79:0.043
THR C:910 C:910 22.0 0.157 H -77.0 3.7 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 20.0 0.143 H -76.0 2.2 4.0 0.029 0.114 B:P05027:0.114
C:Q58K79:0.05
THR D:910 C:910 22.0 0.157 H -76.4 3.4 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 20.0 0.143 H -78.9 6.6 4.0 0.029 0.114 B:P05027:0.114
C:Q58K79:0.057
THR D:910 C:910 23.0 0.164 H -78.8 7.0 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 19.0 0.136 H -74.5 3.7 6.0 0.043 0.093 B:P05027:0.093
C:Q58K79:0.021
THR D:910 C:910 20.0 0.143 H -75.6 4.6 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 23.0 0.164 H -76.6 5.0 7.0 0.05 0.114 B:P05027:0.114
C:Q58K79:0.029
THR D:910 C:910 20.0 0.143 H -77.0 5.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 17.0 0.121 H -76.0 2.1 2.0 0.014 0.107 B:P05027:0.107
C:Q58K79:0.05
THR D:910 C:910 21.0 0.15 H -76.8 3.1 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 22.0 0.157 H -78.3 5.6 6.0 0.043 0.114 B:P05027:0.107
C:Q58K79:0.043
THR D:910 C:910 21.0 0.15 H -78.2 6.5 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:910 A:910 23.0 0.164 H -76.1 2.5 6.0 0.043 0.121 B:P05027:0.114
C:Q58K79:0.05
THR D:910 C:910 22.0 0.157 H -76.0 2.2 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:892 A:910 24.0 0.171 I -114.2 -143.5 24.0 0.171 0.0
THR D:892 C:910 24.0 0.171 I -129.8 -124.7 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:892 A:910 23.0 0.164 H -59.1 -17.8 4.0 0.029 0.135 B:P05027:0.121
C:Q58K79:0.05
THR D:892 C:910 22.0 0.157 H -60.6 -18.3 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:886 A:910 17.0 0.121 H -77.0 -6.9 4.0 0.029 0.092 B:P05027:0.093
THR D:886 C:910 18.0 0.129 H -76.2 -7.7 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 7.0 0.05 0.079 B:None:0.079
 HOH
 6.233
 N
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 THR A:922 A:917 17.0 0.121 H -61.4 -40.5 7.0 0.05 0.071 B:None:0.071
 HOH
 4.841
 OG1
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.4 8.0 0.057 0.072 B:C4IX13:0.071
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -60.9 -33.6 9.0 0.064 0.065 B:C4IX13:0.064
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.4 8.0 0.057 0.072 B:C4IX13:0.071
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.6 7.0 0.05 0.079 B:C4IX13:0.079
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.6 9.0 0.064 0.065 B:C4IX13:0.064
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.6 8.0 0.057 0.072 B:C4IX13:0.071
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.5 7.0 0.05 0.079 B:C4IX13:0.079
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 8.0 0.057 0.072 B:C4IX13:0.071
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 6.0 0.043 0.086 B:C4IX13:0.086
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.1 -33.5 6.0 0.043 0.086 B:C4IX13:0.086
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.6 6.0 0.043 0.086 B:C4IX13:0.086
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 6.0 0.043 0.086 B:C4IX13:0.086
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 18.0 0.129 H -61.0 -33.5 6.0 0.043 0.086 B:C4IX13:0.086
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:922 A:917 17.0 0.121 H -61.4 -38.7 8.0 0.057 0.064 B:C4IX13:0.064
 HOH
 6.248
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 THR A:914 A:914 15.0 0.107 H -64.7 -40.0
af-p13637-f1 1 P13637 88.37 0.0 THR A:907 A:907 13.0 0.093 H -64.5 -39.4
af-p05023-f1 1 P05023 86.71 0.0 THR A:917 A:917 14.0 0.1 H -66.0 -40.6
af-q13733-f1 1 Q13733 80.48 0.0 THR A:923 A:923 15.0 0.107 H -63.6 -42.6