Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160109473 . G A CCDS1196.1:NM_000702.3:c.2884Gct>Act_NP_000693.1:p.962A>T Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ALA A:963 A:963 1.0 0.009 H -57.9 -52.2 1.0 0.009 0.0 CLR
 8.068
 C
 C6
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ALA A:958 A:958 0.0 0.0 H -71.3 -31.4 0.0 0.0 0.0 CLR
PC1
 8.027
8.584
 C
N
 C11
C3F
ALA D:958 C:958 0.0 0.0 H -66.4 -50.5 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ALA A:958 A:958 1.0 0.009 H -60.3 -41.9 1.0 0.009 0.0 PC1
CLR
 8.595
8.129
 N
C
 C3F
C11
ALA D:958 C:958 0.0 0.0 H -69.3 -49.4 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ALA A:963 A:958 0.0 0.0 H -58.2 -58.4 0.0 0.0 0.0 CLR
 7.405
 CB
 C11
ALA D:963 C:958 0.0 0.0 H -58.6 -57.8 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ALA A:963 A:958 0.0 0.0 H -54.4 -47.8 0.0 0.0 0.0 CLR
 7.323
 C
 C7
ALA D:963 C:958 0.0 0.0 H -53.9 -49.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ALA A:963 A:958 0.0 0.0 H -56.1 -53.9 0.0 0.0 0.0 CLR
 7.185
 C
 C7
ALA D:963 C:958 0.0 0.0 H -56.5 -53.2 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ALA A:963 A:958 0.0 0.0 H -57.0 -48.4 0.0 0.0 0.0 CLR
 7.480
 C
 C7
ALA D:963 C:958 0.0 0.0 H -57.3 -48.4 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ALA A:963 A:958 0.0 0.0 H -63.2 -41.9 0.0 0.0 0.0 CLR
 7.856
 C
 C6
ALA D:963 C:958 0.0 0.0 H -64.1 -41.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -61.6 -44.4 0.0 0.0 0.0 CLR
 7.700
 C
 C6
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -63.1 -45.8 0.0 0.0 0.0 CLR
 7.630
 C
 C6
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -62.5 -38.9 0.0 0.0 0.0 CLR
 7.756
 C
 C6
ALA C:958 C:958 0.0 0.0 H -63.8 -40.0 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -61.9 -39.1 0.0 0.0 0.0 CLR
 7.765
 C
 C6
ALA D:958 C:958 0.0 0.0 H -63.5 -41.3 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -64.4 -44.4 0.0 0.0 0.0 CLR
 7.649
 C
 C6
ALA D:958 C:958 1.0 0.009 H -65.4 -43.7 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -62.0 -36.7 0.0 0.0 0.0 CLR
 7.886
 C
 C6
ALA D:958 C:958 0.0 0.0 H -61.8 -35.4 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 1.0 0.009 H -62.0 -46.6 1.0 0.009 0.0 CLR
 7.920
 C
 C6
ALA D:958 C:958 1.0 0.009 H -62.7 -47.0 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -62.7 -38.0 0.0 0.0 0.0 CLR
 7.567
 C
 C6
ALA D:958 C:958 0.0 0.0 H -63.5 -40.7 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -62.5 -42.5 0.0 0.0 0.0 CLR
 7.713
 C
 C7
ALA D:958 C:958 0.0 0.0 H -63.6 -42.9 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ALA A:958 A:958 0.0 0.0 H -62.9 -38.8 0.0 0.0 0.0 CLR
 7.806
 C
 C6
ALA D:958 C:958 0.0 0.0 H -63.4 -40.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ALA A:940 A:958 0.0 0.0 H -35.9 -61.6 0.0 0.0 0.0
ALA D:940 C:958 1.0 0.009 H -47.4 -67.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ALA A:940 A:958 0.0 0.0 H -49.2 -61.6 0.0 0.0 0.0
ALA D:940 C:958 0.0 0.0 H -48.8 -62.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ALA A:934 A:958 3.0 0.026 H -52.5 -59.5 3.0 0.026 0.0
ALA D:934 C:958 4.0 0.035 H -52.2 -59.5 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ALA A:970 A:965 0.0 0.0 H -58.7 -47.1 0.0 0.0 0.0 HOH
 7.164
 CB
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ALA A:970 A:965 0.0 0.0 H -64.0 -50.8 0.0 0.0 0.0 HOH
 7.525
 CB
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.8 -47.1 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.1 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.2 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.2 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.2 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.6 -47.2 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.8 -47.1 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.2 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.8 -47.1 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.8 -47.0 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.1 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.6 -47.3 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.8 -47.1 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.2 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.2 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.1 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.7 -47.1 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.6 -47.2 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -58.6 -47.2 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:970 A:965 0.0 0.0 H -60.8 -49.9 0.0 0.0 0.0 HOH
 7.201
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ALA A:962 A:962 0.0 0.0 H -59.3 -43.0
af-p13637-f1 1 P13637 88.37 0.0 ALA A:955 A:955 0.0 0.0 H -59.3 -42.5
af-p05023-f1 1 P05023 86.71 0.0 ALA A:965 A:965 0.0 0.0 H -58.8 -43.6
af-q13733-f1 1 Q13733 80.48 0.0 ALA A:971 A:971 0.0 0.0 H -59.4 -41.8