Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160109525 . C A CCDS1196.1:NM_000702.3:c.2936cCg>cAg_NP_000693.1:p.979P>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 PRO A:980 A:980 80.0 0.552 -57.2 146.6 6.0 0.041 0.511 B:G3MWR4:0.062
C:Q04645:0.497
 CLR
 7.834
 CB
 O1
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 PRO A:975 A:975 78.0 0.538 -49.3 146.2 14.0 0.097 0.441 B:P05027:0.048
C:Q58K79:0.4
 CLR
 7.852
 CB
 O1
PRO D:975 C:975 73.0 0.503 -58.6 167.5 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 PRO A:975 A:975 76.0 0.524 -50.2 157.1 15.0 0.103 0.421 B:P05027:0.055
C:Q58K79:0.386
 CLR
 7.821
 CB
 O1
PRO D:975 C:975 72.0 0.497 -60.9 171.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 PRO A:980 A:975 70.0 0.483 -51.3 162.2 25.0 0.172 0.311 B:P05027:0.028
C:Q58K79:0.29
 CLR
 9.198
 C
 C2
PRO D:980 C:975 71.0 0.49 -49.9 163.0 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 PRO A:980 A:975 75.0 0.517 -60.6 134.4 5.0 0.034 0.483 B:P05027:0.069
C:Q58K79:0.469
 1DS
CLR
 8.656
8.215
 O
CB
 O3
C4
PRO D:980 C:975 76.0 0.524 -61.9 133.9 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 PRO A:980 A:975 82.0 0.566 -56.1 155.4 6.0 0.041 0.525 B:P05027:0.083
C:Q58K79:0.497
 CLR
 8.375
 CB
 C4
PRO D:980 C:975 80.0 0.552 -55.9 156.1 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 PRO A:980 A:975 77.0 0.531 -60.0 129.3 7.0 0.048 0.483 B:P05027:0.083
C:Q58K79:0.469
 GLC
CLR
 8.345
8.269
 O
C
 C6
C4
PRO D:980 C:975 77.0 0.531 -59.8 129.2 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 PRO A:980 A:975 72.0 0.497 -65.6 156.5 4.0 0.028 0.469 B:P05027:0.076
C:Q58K79:0.441
 CLR
 8.592
 C
 C4
PRO D:980 C:975 75.0 0.517 -65.7 155.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 75.0 0.517 -64.0 155.3 5.0 0.034 0.483 B:P05027:0.069
C:Q58K79:0.462
 CLR
 8.214
 CB
 O1
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 74.0 0.51 -62.7 159.5 5.0 0.034 0.476 B:P05027:0.069
C:Q58K79:0.448
 CLR
 7.965
 CB
 O1
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 77.0 0.531 -63.5 153.8 6.0 0.041 0.49 B:P05027:0.076
F:Q58K79:0.469
 CLR
 8.419
 C
 C4
PRO C:975 C:975 78.0 0.538 -63.5 153.4 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 76.0 0.524 -63.6 153.5 6.0 0.041 0.483 B:P05027:0.076
C:Q58K79:0.469
 CLR
 8.359
 C
 C4
PRO D:975 C:975 77.0 0.531 -63.2 152.1 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 75.0 0.517 -66.0 156.4 5.0 0.034 0.483 B:P05027:0.069
C:Q58K79:0.462
 CLR
 8.358
 C
 C4
PRO D:975 C:975 78.0 0.538 -65.9 154.9 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 77.0 0.531 -64.7 159.7 7.0 0.048 0.483 B:P05027:0.076
C:Q58K79:0.455
 CLR
 8.556
 C
 C4
PRO D:975 C:975 80.0 0.552 -64.6 159.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 76.0 0.524 -64.6 160.7 8.0 0.055 0.469 B:P05027:0.069
C:Q58K79:0.434
 CLR
 8.605
 C
 C4
PRO D:975 C:975 75.0 0.517 -64.1 159.6 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 77.0 0.531 -63.4 152.4 6.0 0.041 0.49 B:P05027:0.083
C:Q58K79:0.469
 CLR
 8.365
 C
 C4
PRO D:975 C:975 79.0 0.545 -63.3 152.1 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 74.0 0.51 -64.9 156.5 3.0 0.021 0.489 B:P05027:0.076
C:Q58K79:0.462
 CLR
 8.455
 C
 C4
PRO D:975 C:975 77.0 0.531 -65.6 156.6 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:975 A:975 76.0 0.524 -63.6 153.1 6.0 0.041 0.483 B:P05027:0.069
C:Q58K79:0.462
 CLR
 8.503
 C
 C4
PRO D:975 C:975 78.0 0.538 -62.9 152.8 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 PRO A:957 A:975 9.0 0.062 -93.5 164.9 2.0 0.014 0.048 C:Q58K79:0.048
PRO D:957 C:975 1.0 0.007 -89.1 117.4 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 PRO A:957 A:975 80.0 0.552 -48.7 148.1 25.0 0.172 0.38 B:P05027:0.007
C:Q58K79:0.379
PRO D:957 C:975 81.0 0.559 -47.4 147.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 PRO A:951 A:975 73.0 0.503 -60.7 157.5 10.0 0.069 0.434 B:P05027:0.097
C:Q58K79:0.393
PRO D:951 C:975 75.0 0.517 -59.8 158.5 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 PRO A:987 A:982 80.0 0.552 -62.2 134.9 4.0 0.028 0.524 B:None:0.124
C:Q70Q12:0.469
 HOH
 8.712
 N
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 PRO A:987 A:982 79.0 0.545 -68.0 144.0 5.0 0.034 0.511 B:None:0.11
C:Q70Q12:0.469
 HOH
 5.547
 O
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.3 135.0 5.0 0.034 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 4.0 0.028 0.524 C:Q70Q12:0.469
B:C4IX13:0.117
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.3 134.9 5.0 0.034 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.3 134.9 5.0 0.034 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 81.0 0.559 -62.2 135.0 5.0 0.034 0.525 B:C4IX13:0.117
C:Q70Q12:0.462
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 81.0 0.559 -62.2 134.9 6.0 0.041 0.518 B:C4IX13:0.117
C:Q70Q12:0.455
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 B:C4IX13:0.103
C:Q70Q12:0.455
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 C:Q70Q12:0.462
B:C4IX13:0.117
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 81.0 0.559 -62.2 134.9 6.0 0.041 0.518 B:C4IX13:0.117
C:Q70Q12:0.462
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 4.0 0.028 0.524 B:C4IX13:0.124
C:Q70Q12:0.462
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.3 135.0 5.0 0.034 0.518 C:Q70Q12:0.455
B:C4IX13:0.11
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 B:C4IX13:0.124
C:Q70Q12:0.462
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 135.0 5.0 0.034 0.518 B:C4IX13:0.124
C:Q70Q12:0.462
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.8 5.0 0.034 0.518 B:C4IX13:0.124
C:Q70Q12:0.469
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.3 134.9 5.0 0.034 0.518 B:C4IX13:0.131
C:Q70Q12:0.462
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 80.0 0.552 -62.2 134.9 5.0 0.034 0.518 B:C4IX13:0.124
C:Q70Q12:0.462
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:987 A:982 79.0 0.545 -61.4 134.4 3.0 0.021 0.524 B:C4IX13:0.117
C:Q70Q12:0.476
 HOH
 8.853
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 PRO A:979 A:979 81.0 0.559 -65.8 131.5
af-p13637-f1 1 P13637 88.37 0.0 PRO A:972 A:972 80.0 0.552 -65.4 130.2
af-p05023-f1 1 P05023 86.71 0.0 PRO A:982 A:982 82.0 0.566 -66.1 131.6
af-q13733-f1 1 Q13733 80.48 0.0 PRO A:988 A:988 81.0 0.559 -63.1 135.2