Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160109745 . G A CCDS1196.1:NM_000702.3:c.3005cGa>cAa_NP_000693.1:p.1002R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:1003 A:1003 16.0 0.071 H -66.5 -44.5 16.0 0.071 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:998 A:998 4.0 0.018 H -56.1 -41.8 4.0 0.018 0.0 PC1
 8.475
 N
 C37
ARG D:998 C:998 5.0 0.022 H -64.2 -44.3 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:998 A:998 2.0 0.009 H -59.3 -45.5 2.0 0.009 0.0 PC1
HOH
 8.420
9.715
 N
O
 C35
O
ARG D:998 C:998 4.0 0.018 H -63.6 -50.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:1003 A:998 7.0 0.031 H -46.0 -70.4 7.0 0.031 0.0
ARG D:1003 C:998 8.0 0.036 H -46.0 -70.2 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:1003 A:998 12.0 0.053 H -64.8 -43.7 12.0 0.053 0.0 CE1
 8.119
 O
 O25
ARG D:1003 C:998 13.0 0.058 H -64.7 -43.5 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1003 A:998 12.0 0.053 H -66.4 -50.1 12.0 0.053 0.0
ARG D:1003 C:998 11.0 0.049 H -66.8 -46.3 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1003 A:998 11.0 0.049 H -67.3 -45.0 11.0 0.049 0.0
ARG D:1003 C:998 12.0 0.053 H -67.5 -44.8 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:1003 A:998 10.0 0.044 H -64.7 -52.1 10.0 0.044 0.0
ARG D:1003 C:998 9.0 0.04 H -65.1 -51.7 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 16.0 0.071 H -64.1 -51.9 16.0 0.071 0.0 PCW
PCW
PCW
 8.029
9.462
9.081
 O
N
CA
 O2P
O11
C12
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 15.0 0.067 H -62.9 -53.7 15.0 0.067 0.0 PCW
PCW
 8.773
9.087
 O
O
 O2P
O2P
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 11.0 0.049 H -63.5 -53.5 11.0 0.049 0.0 PCW
 9.439
 O
 O2P
ARG C:998 C:998 13.0 0.058 H -63.6 -53.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 10.0 0.044 H -64.0 -53.6 10.0 0.044 0.0
ARG D:998 C:998 13.0 0.058 H -63.7 -53.8 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 14.0 0.062 H -64.7 -51.4 14.0 0.062 0.0
ARG D:998 C:998 12.0 0.053 H -65.8 -51.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 14.0 0.062 H -65.3 -50.5 14.0 0.062 0.0
ARG D:998 C:998 13.0 0.058 H -65.4 -50.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 12.0 0.053 H -62.0 -49.2 12.0 0.053 0.0
ARG D:998 C:998 14.0 0.062 H -62.6 -48.8 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 12.0 0.053 H -63.0 -53.1 12.0 0.053 0.0
ARG D:998 C:998 13.0 0.058 H -64.2 -53.4 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 11.0 0.049 H -62.8 -54.0 11.0 0.049 0.0
ARG D:998 C:998 9.0 0.04 H -63.8 -53.8 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:998 A:998 13.0 0.058 H -63.6 -53.2 13.0 0.058 0.0
ARG D:998 C:998 13.0 0.058 H -64.5 -53.5 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:980 A:998 21.0 0.093 H -54.9 -47.7 21.0 0.093 0.0
ARG D:980 C:998 10.0 0.044 H -34.9 -53.7 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:980 A:998 9.0 0.04 H -57.4 -67.2 9.0 0.04 0.0
ARG D:980 C:998 10.0 0.044 H -60.4 -64.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:974 A:998 13.0 0.058 H -51.3 -43.5 13.0 0.058 0.0
ARG D:974 C:998 14.0 0.062 H -51.2 -43.0 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0 HOH
 6.061
 C
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:1010 A:1005 10.0 0.044 H -69.0 -35.1 10.0 0.044 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.9 -48.2 16.0 0.071 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.9 -48.2 16.0 0.071 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.7 -48.2 16.0 0.071 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.3 16.0 0.071 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.9 -48.2 16.0 0.071 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.3 16.0 0.071 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.7 -48.3 16.0 0.071 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.9 -48.3 16.0 0.071 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.3 16.0 0.071 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.9 -48.2 16.0 0.071 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.3 16.0 0.071 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.8 -48.2 16.0 0.071 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 16.0 0.071 H -55.7 -48.2 16.0 0.071 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1010 A:1005 14.0 0.062 H -62.6 -46.0 14.0 0.062 0.0 HOH
 6.042
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:1002 A:1002 9.0 0.04 H -56.7 -49.2
af-p13637-f1 1 P13637 88.37 0.0 ARG A:995 A:995 9.0 0.04 H -56.1 -48.9
af-p05023-f1 1 P05023 86.71 0.0 ARG A:1005 A:1005 8.0 0.036 H -56.9 -49.9
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:1011 A:1011 7.0 0.031 H -56.4 -48.0