Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160109760 . G A CCDS1196.1:NM_000702.3:c.3020cGg>cAg_NP_000693.1:p.1007R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:1008 A:1008 70.0 0.311 H -66.2 -46.4 70.0 0.311 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:1003 A:1003 59.0 0.262 H -63.4 -30.6 59.0 0.262 0.0 PC1
HOH
 3.208
8.566
 NH2
C
 O32
O
ARG D:1003 C:1003 58.0 0.258 H -67.0 -22.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:1003 A:1003 60.0 0.267 H -63.9 -29.7 60.0 0.267 0.0 PC1
HOH
 3.219
8.488
 NH2
C
 O32
O
ARG D:1003 C:1003 55.0 0.244 H -62.7 -23.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:1008 A:1003 91.0 0.404 H -46.0 -59.1 91.0 0.404 0.0
ARG D:1008 C:1003 92.0 0.409 H -46.2 -59.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:1008 A:1003 72.0 0.32 H -66.2 -49.4 72.0 0.32 0.0 CE1
 8.715
 N
 C26
ARG D:1008 C:1003 71.0 0.316 H -65.1 -49.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1008 A:1003 62.0 0.276 H -69.6 -43.2 62.0 0.276 0.0
ARG D:1008 C:1003 61.0 0.271 H -69.9 -43.1 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1008 A:1003 71.0 0.316 H -68.8 -41.8 71.0 0.316 0.0
ARG D:1008 C:1003 71.0 0.316 H -67.7 -42.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:1008 A:1003 61.0 0.271 H -70.7 -51.9 61.0 0.271 0.0
ARG D:1008 C:1003 59.0 0.262 H -71.6 -52.3 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 109.0 0.484 H -67.1 -53.8 109.0 0.484 0.0 PCW
PCW
PCW
 6.952
9.722
9.248
 C
C
N
 O2P
O1P
O2P
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 108.0 0.48 H -72.8 -47.7 108.0 0.48 0.0 PCW
PCW
PCW
 7.556
9.917
9.350
 C
C
N
 O2P
O1P
O2P
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 61.0 0.271 H -69.6 -57.9 61.0 0.271 0.0 PCW
CLR
 9.598
8.091
 N
NH1
 O2P
C4
ARG C:1003 C:1003 56.0 0.249 H -71.6 -59.0 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 61.0 0.271 H -68.7 -58.8 61.0 0.271 0.0
ARG D:1003 C:1003 60.0 0.267 H -70.1 -59.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 65.0 0.289 H -73.5 -54.8 65.0 0.289 0.0
ARG D:1003 C:1003 64.0 0.284 H -73.5 -53.0 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 71.0 0.316 H -69.2 -51.5 71.0 0.316 0.0
ARG D:1003 C:1003 75.0 0.333 H -68.9 -53.4 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 62.0 0.276 H -74.2 -55.6 62.0 0.276 0.0 CLR
 8.023
 NH1
 C4
ARG D:1003 C:1003 66.0 0.293 H -74.0 -56.3 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 65.0 0.289 H -70.1 -57.6 65.0 0.289 0.0 PCW
 6.333
 O
 C7
ARG D:1003 C:1003 58.0 0.258 H -71.5 -58.5 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 66.0 0.293 H -70.7 -51.5 66.0 0.293 0.0 PCW
 6.979
 O
 C7
ARG D:1003 C:1003 65.0 0.289 H -71.7 -53.0 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1003 A:1003 65.0 0.289 H -69.5 -56.0 65.0 0.289 0.0
ARG D:1003 C:1003 57.0 0.253 H -69.8 -57.7 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:985 A:1003 65.0 0.289 H -78.0 -65.2 65.0 0.289 0.0
ARG D:985 C:1003 69.0 0.307 H -69.2 -44.0 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:985 A:1003 58.0 0.258 H -56.3 -14.4 58.0 0.258 0.0
ARG D:985 C:1003 57.0 0.253 H -56.2 -13.1 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:979 A:1003 50.0 0.222 H -64.0 -53.4 50.0 0.222 0.0
ARG D:979 C:1003 48.0 0.213 H -63.0 -53.2 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:1015 A:1010 52.0 0.231 H -62.5 -45.9 52.0 0.231 0.0 HOH
 2.747
 NH2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:1015 A:1010 44.0 0.196 H -65.3 -52.5 44.0 0.196 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.8 51.0 0.227 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.6 -45.9 51.0 0.227 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.6 -45.8 51.0 0.227 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -46.0 51.0 0.227 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.6 -45.9 51.0 0.227 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.6 -45.8 51.0 0.227 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.5 -45.9 51.0 0.227 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.6 -45.8 51.0 0.227 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 52.0 0.231 H -62.6 -45.9 52.0 0.231 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 51.0 0.227 H -62.6 -45.7 51.0 0.227 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 52.0 0.231 H -62.7 -45.8 52.0 0.231 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1015 A:1010 48.0 0.213 H -59.6 -47.2 48.0 0.213 0.0 HOH
 2.818
 NH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:1007 A:1007 55.0 0.244 H -71.2 -35.7
af-p13637-f1 1 P13637 88.37 0.0 ARG A:1000 A:1000 51.0 0.227 H -69.8 -35.9
af-p05023-f1 1 P05023 86.71 0.0 ARG A:1010 A:1010 52.0 0.231 H -64.4 -37.7
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:1016 A:1016 56.0 0.249 H -70.9 -36.7