Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160109763 . G A CCDS1196.1:NM_000702.3:c.3023cGg>cAg_NP_000693.1:p.1008R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:1009 A:1009 164.0 0.729 H -71.5 -37.1 164.0 0.729 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:1004 A:1004 195.0 0.867 H -113.8 1.6 195.0 0.867 0.0 PC1
HOH
 4.675
3.334
 CG
NH1
 C13
O
ARG D:1004 C:1004 193.0 0.858 H -107.4 -15.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:1004 A:1004 201.0 0.893 H -111.6 1.9 201.0 0.893 0.0 PC1
HOH
 4.817
3.141
 CG
NH1
 C13
O
ARG D:1004 C:1004 190.0 0.844 H -109.8 -11.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:1009 A:1004 230.0 1.0 H -70.0 -39.3 230.0 1.0 0.0
ARG D:1009 C:1004 229.0 1.0 H -69.6 -39.2 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:1009 A:1004 161.0 0.716 H -65.5 -47.4 161.0 0.716 0.0 CE1
 7.082
 NH2
 O25
ARG D:1009 C:1004 160.0 0.711 H -65.6 -50.2 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1009 A:1004 163.0 0.724 H -78.1 -23.9 163.0 0.724 0.0
ARG D:1009 C:1004 167.0 0.742 H -77.5 -24.1 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1009 A:1004 160.0 0.711 H -76.9 -37.5 160.0 0.711 0.0
ARG D:1009 C:1004 160.0 0.711 H -76.8 -37.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:1009 A:1004 163.0 0.724 H -76.4 -23.5 163.0 0.724 0.0
ARG D:1009 C:1004 168.0 0.747 H -74.7 -23.6 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 191.0 0.849 H -81.2 -17.3 191.0 0.849 0.0 PCW
PCW
PCW
 2.966
2.407
7.690
 NH2
NH1
C
 O1P
O1P
O2P
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 193.0 0.858 H -84.3 -20.9 193.0 0.858 0.0 PCW
PCW
PCW
 3.174
2.697
7.948
 NH2
NH1
C
 O1P
O1P
O2P
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 172.0 0.764 H -67.0 -38.6 172.0 0.764 0.0 PCW
 7.180
 NH2
 O1P
ARG C:1004 C:1004 144.0 0.64 H -66.6 -35.5 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 161.0 0.716 H -65.9 -39.8 161.0 0.716 0.0
ARG D:1004 C:1004 167.0 0.742 H -66.8 -37.3 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 157.0 0.698 H -74.5 -33.3 157.0 0.698 0.0
ARG D:1004 C:1004 163.0 0.724 H -74.1 -34.7 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 166.0 0.738 H -78.2 -26.6 166.0 0.738 0.0
ARG D:1004 C:1004 171.0 0.76 H -77.9 -25.6 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 163.0 0.724 H -71.4 -31.0 163.0 0.724 0.0
ARG D:1004 C:1004 169.0 0.751 H -70.8 -30.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 158.0 0.702 H -65.5 -40.9 158.0 0.702 0.0 PCW
PCW
 2.826
8.521
 NE
NH2
 O1P
O31
ARG D:1004 C:1004 167.0 0.742 H -66.2 -37.6 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 160.0 0.711 H -77.1 -32.1 160.0 0.711 0.0 PCW
 3.452
 CD
 O1P
ARG D:1004 C:1004 160.0 0.711 H -75.1 -31.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1004 A:1004 163.0 0.724 H -66.9 -38.9 163.0 0.724 0.0
ARG D:1004 C:1004 165.0 0.733 H -68.4 -36.1 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:986 A:1004 222.0 0.987 H -40.9 -32.5 222.0 0.987 0.0
ARG D:986 C:1004 214.0 0.951 H -67.5 -8.7 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:986 A:1004 214.0 0.951 H -99.1 -30.0 214.0 0.951 0.0
ARG D:986 C:1004 215.0 0.956 H -99.6 -31.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:980 A:1004 196.0 0.871 H -61.1 -47.6 196.0 0.871 0.0
ARG D:980 C:1004 197.0 0.876 H -61.1 -48.3 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:1016 A:1011 193.0 0.858 H -64.9 -18.3 193.0 0.858 0.0 HOH
 7.047
 C
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:1016 A:1011 198.0 0.88 H -49.8 -49.0 198.0 0.88 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.8 -18.4 192.0 0.853 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.3 192.0 0.853 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.4 192.0 0.853 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.8 -18.4 192.0 0.853 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.4 192.0 0.853 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 193.0 0.858 H -64.9 -18.4 193.0 0.858 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.8 -18.3 192.0 0.853 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.4 192.0 0.853 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 193.0 0.858 H -64.9 -18.3 193.0 0.858 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.3 192.0 0.853 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.3 192.0 0.853 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 193.0 0.858 H -64.8 -18.5 193.0 0.858 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.3 192.0 0.853 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.4 192.0 0.853 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.4 192.0 0.853 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.4 192.0 0.853 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -64.9 -18.3 192.0 0.853 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 192.0 0.853 H -65.0 -18.3 192.0 0.853 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 193.0 0.858 H -65.0 -18.3 193.0 0.858 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:1016 A:1011 193.0 0.858 H -61.5 -28.4 193.0 0.858 0.0 HOH
 6.919
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:1008 A:1008 182.0 0.809 H -78.3 -31.6
af-p13637-f1 1 P13637 88.37 0.0 ARG A:1001 A:1001 203.0 0.902 H -77.2 -29.5
af-p05023-f1 1 P05023 86.71 0.0 ARG A:1011 A:1011 200.0 0.889 H -79.2 -25.4
af-q13733-f1 1 Q13733 80.48 0.0 GLN A:1017 A:1017 115.0 0.639 H -76.2 -32.4