Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160109767 . T A CCDS1196.1:NM_000702.3:c.3027taT>taA_NP_000693.1:p.1009Y>* Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:1010 A:1010 136.0 0.604 -120.9 80.7 136.0 0.604 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:1005 A:1005 133.0 0.591 -138.6 69.8 133.0 0.591 0.0 PC1
HOH
 8.499
5.969
 N
CG
 C13
O
ARG D:1005 C:1005 144.0 0.64 S -136.9 72.6 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:1005 A:1005 136.0 0.604 -140.1 66.8 136.0 0.604 0.0 PC1
HOH
 8.453
6.185
 N
CG
 C13
O
ARG D:1005 C:1005 144.0 0.64 S -139.4 66.9 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:1010 A:1005 147.0 0.653 -129.4 137.5 147.0 0.653 0.0
ARG D:1010 C:1005 146.0 0.649 -129.1 137.5 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:1010 A:1005 145.0 0.644 -116.3 91.4 145.0 0.644 0.0 CE1
 2.790
 NH1
 O25
ARG D:1010 C:1005 144.0 0.64 -113.0 98.3 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1010 A:1005 154.0 0.684 -133.1 82.4 154.0 0.684 0.0
ARG D:1010 C:1005 154.0 0.684 -133.5 82.1 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:1010 A:1005 138.0 0.613 -119.4 85.1 138.0 0.613 0.0
ARG D:1010 C:1005 138.0 0.613 -119.5 85.3 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:1010 A:1005 123.0 0.547 -125.9 82.5 123.0 0.547 0.0
ARG D:1010 C:1005 125.0 0.556 -126.7 81.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 180.0 0.8 -132.6 69.2 180.0 0.8 0.0 PCW
PCW
PCW
 3.185
8.448
3.159
 NH1
NH1
NH1
 O4P
O2P
O2
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 181.0 0.804 -130.0 69.4 181.0 0.804 0.0 PCW
PCW
PCW
 3.178
8.632
3.669
 CD
NH1
NE
 O2P
O2P
O1P
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 161.0 0.716 -113.1 87.1 161.0 0.716 0.0 PCW
 2.477
 NE
 O1P
ARG C:1005 C:1005 146.0 0.649 -112.6 86.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 123.0 0.547 -112.8 86.9 123.0 0.547 0.0
ARG D:1005 C:1005 116.0 0.516 -111.2 85.4 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 128.0 0.569 -117.5 77.5 128.0 0.569 0.0
ARG D:1005 C:1005 135.0 0.6 -117.0 80.2 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 114.0 0.507 -115.8 86.7 114.0 0.507 0.0
ARG D:1005 C:1005 117.0 0.52 -115.5 86.8 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 114.0 0.507 -118.2 77.2 114.0 0.507 0.0
ARG D:1005 C:1005 113.0 0.502 -117.7 79.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 126.0 0.56 -114.3 87.5 126.0 0.56 0.0 PCW
PCW
 5.746
2.695
 CG
NH2
 O1P
O1P
ARG D:1005 C:1005 118.0 0.524 -111.9 86.7 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 124.0 0.551 -114.3 84.8 124.0 0.551 0.0 PCW
 6.899
 CG
 O1P
ARG D:1005 C:1005 120.0 0.533 -115.5 84.2 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:1005 A:1005 121.0 0.538 -113.3 86.6 121.0 0.538 0.0
ARG D:1005 C:1005 113.0 0.502 -111.9 84.7 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:987 A:1005 150.0 0.667 S -120.6 88.0 150.0 0.667 0.0
ARG D:987 C:1005 111.0 0.493 S -134.8 106.2 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:987 A:1005 166.0 0.738 S -133.7 98.9 166.0 0.738 0.0
ARG D:987 C:1005 166.0 0.738 S -132.9 97.5 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:981 A:1005 174.0 0.773 -110.9 83.5 174.0 0.773 0.0
ARG D:981 C:1005 178.0 0.791 -110.5 83.5 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0 HOH
 3.387
 OG
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 SER A:1017 A:1012 53.0 0.461 -112.1 77.7 53.0 0.461 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.1 59.0 0.513 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.5 92.0 59.0 0.513 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.1 59.0 0.513 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.7 92.1 59.0 0.513 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.1 59.0 0.513 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.1 59.0 0.513 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.5 92.0 59.0 0.513 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.1 59.0 0.513 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 92.0 59.0 0.513 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.7 92.0 59.0 0.513 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -150.6 91.9 59.0 0.513 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:1017 A:1012 59.0 0.513 -142.7 91.7 59.0 0.513 0.0 HOH
 3.265
 OG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 TYR A:1009 A:1009 131.0 0.57 S -128.3 69.2
af-p13637-f1 1 P13637 88.37 0.0 ASN A:1002 A:1002 96.0 0.6 S -130.4 69.8
af-p05023-f1 1 P05023 86.71 0.0 ARG A:1012 A:1012 182.0 0.809 S -132.5 69.3
af-q13733-f1 1 Q13733 80.48 0.0 HIS A:1018 A:1018 114.0 0.585 S -125.7 73.9