Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 16475203 | . | C | A | CCDS169.1:NM_004431.3:c.493Gtg>Ttg_NP_004422.2:p.165V>L | Homo sapiens EPH receptor A2 (EPHA2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3fl7 | 1 | Q8N3Z2 | 99.42 | 0.0 |
X-RAY |
2009-01-27 | VAL | A:170 | A:165 | 70.0 | 0.452 | E | -123.7 | 138.2 | 70.0 | 0.452 | 0.0 |
NA HOH |
5.098 2.809 |
O N |
NA O |
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2x10 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-03-16 | VAL | A:167 | A:165 | 64.0 | 0.413 | E | -109.2 | 136.0 | 64.0 | 0.413 | 0.0 | ||||||
2x11 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-03-16 | VAL | A:167 | A:165 | 78.0 | 0.503 | E | -123.6 | 122.5 | 78.0 | 0.503 | 0.0 | ||||||
3mx0 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-06-30 | VAL | A:139 | A:165 | 81.0 | 0.523 | E | -108.7 | 120.2 | 81.0 | 0.523 | 0.0 | ||||||
VAL | C:139 | C:165 | 71.0 | 0.458 | E | -82.1 | 140.7 | NA | NA | NA | |||||||||||||
3mbw | 1 | P29317 | 99.03 | 0.0 |
X-RAY |
2010-06-09 | VAL | A:169 | A:165 | 84.0 | 0.542 | E | -116.8 | 121.6 | 84.0 | 0.542 | 0.0 |
UNX HOH |
5.521 3.909 |
O O |
UNK O |
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3czu | 1 | P29317 | 98.37 | 2e-127 |
X-RAY |
2008-08-12 | VAL | A:170 | A:165 | 76.0 | 0.49 | E | -124.5 | 127.3 | 76.0 | 0.49 | 0.0 |
HOH |
2.955 |
N |
O |
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3c8x | 1 | P29317 | 98.37 | 2e-127 |
X-RAY |
2008-03-25 | VAL | A:169 | A:165 | 88.0 | 0.568 | E | -128.3 | 122.8 | 77.0 | 0.497 | 0.071 |
A:P29317:0.071 |
HOH |
3.061 |
N |
O |
|
3skj | 3 | P29317 | 98.37 | 2e-127 |
X-RAY |
2011-08-31 | VAL | E:169 | E:141 | 74.0 | 0.477 | E | -123.0 | 127.6 | 74.0 | 0.477 | 0.0 |
HOH |
4.238 |
CG2 |
O |
||
VAL | F:169 | F:141 | 93.0 | 0.6 | E | -122.0 | 137.3 | NA | NA | NA | |||||||||||||
7czf | 1 | P29317 | 98.36 | 4e-127 |
X-RAY |
2020-10-21 | VAL | A:138 | A:165 | 41.0 | 0.265 | E | -125.0 | 126.9 | 41.0 | 0.265 | 0.0 | ||||||
VAL | D:138 | D:165 | 48.0 | 0.31 | E | -114.9 | 133.0 | NA | NA | NA | |||||||||||||
7b7n | 1 | P29317 | 99.45 | 7e-127 |
X-RAY |
2020-12-30 | VAL | A:143 | E:165 | 73.0 | 0.471 | E | -114.1 | 112.9 | 73.0 | 0.471 | 0.0 |
HOH |
6.479 |
CG1 |
O |
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6rw2 | 1 | P29317 | 96.7 | 6e-124 |
X-RAY |
2020-04-08 | VAL | A:157 | A:165 | 76.0 | 0.49 | E | -123.5 | 117.7 | 76.0 | 0.49 | 0.0 |
HOH |
3.019 |
N |
O |
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7cze | 3 | P29317 | 100.0 | 1e-123 |
X-RAY |
2020-10-21 | VAL | I:140 | I:165 | 81.0 | 0.523 | E | -130.9 | 109.5 | 81.0 | 0.523 | 0.0 | ||||||
VAL | J:140 | J:165 | 78.0 | 0.503 | E | -129.1 | 109.5 | NA | NA | NA | |||||||||||||
VAL | K:140 | K:165 | 78.0 | 0.503 | E | -131.0 | 109.3 | NA | NA | NA | |||||||||||||
VAL | L:140 | L:165 | 79.0 | 0.51 | E | -131.0 | 109.2 | NA | NA | NA | |||||||||||||
3hei | 1 | P29317 | 100.0 | 7e-123 |
X-RAY |
2009-06-30 | VAL | A:138 | A:138 | 73.0 | 0.471 | E | -126.7 | 130.0 | 73.0 | 0.471 | 0.0 |
HOH |
2.581 |
O |
O |
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VAL | C:138 | C:138 | 71.0 | 0.458 | E | -127.1 | 127.8 | NA | NA | NA | |||||||||||||
VAL | E:138 | E:138 | 75.0 | 0.484 | E | -131.7 | 129.4 | NA | NA | NA | |||||||||||||
VAL | G:138 | G:138 | 68.0 | 0.439 | E | -126.1 | 124.7 | NA | NA | NA | |||||||||||||
VAL | I:138 | I:138 | 75.0 | 0.484 | E | -125.8 | 118.5 | NA | NA | NA | |||||||||||||
VAL | K:138 | K:138 | 71.0 | 0.458 | E | -133.0 | 121.9 | NA | NA | NA | |||||||||||||
VAL | M:138 | M:138 | 72.0 | 0.465 | E | -126.5 | 130.3 | NA | NA | NA | |||||||||||||
VAL | O:138 | O:138 | 79.0 | 0.51 | E | -118.1 | 131.8 | NA | NA | NA | |||||||||||||
3hpn | 1 | P29317 | 100.0 | 7e-123 |
X-RAY |
2009-06-30 | VAL | A:138 | A:138 | 74.0 | 0.477 | E | -122.4 | 124.6 | 74.0 | 0.477 | 0.0 |
HOH |
2.490 |
O |
O |
||
VAL | B:138 | B:138 | 75.0 | 0.484 | E | -115.7 | 129.3 | NA | NA | NA | |||||||||||||
VAL | C:138 | C:138 | 75.0 | 0.484 | E | -119.5 | 129.9 | NA | NA | NA | |||||||||||||
VAL | D:138 | D:138 | 74.0 | 0.477 | E | -121.2 | 126.6 | NA | NA | NA | |||||||||||||
VAL | E:138 | E:138 | 74.0 | 0.477 | E | -119.0 | 128.8 | NA | NA | NA | |||||||||||||
VAL | F:138 | F:138 | 76.0 | 0.49 | E | -122.4 | 122.7 | NA | NA | NA | |||||||||||||
6b9l | 1 | P29317 | 100.0 | 9e-123 |
X-RAY |
2018-10-17 | VAL | A:160 | A:165 | 71.0 | 0.458 | E | -117.6 | 120.0 | 71.0 | 0.458 | 0.0 | ||||||
VAL | B:160 | B:165 | 72.0 | 0.465 | E | -129.1 | 117.4 | 72.0 | 0.465 | 0.0 | |||||||||||||
VAL | C:160 | C:165 | 69.0 | 0.445 | E | -121.2 | 126.8 | 69.0 | 0.445 | 0.0 | |||||||||||||
VAL | D:160 | D:165 | 70.0 | 0.452 | E | -130.9 | 124.9 | 70.0 | 0.452 | 0.0 | |||||||||||||
6njz | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | VAL | A:145 | A:165 | 70.0 | 0.452 | E | -129.1 | 127.3 | 70.0 | 0.452 | 0.0 |
GOL GOL HOH |
7.757 9.199 2.095 |
HG12 HG12 H |
HO3 H31 O |
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VAL | B:145 | B:165 | 73.0 | 0.471 | E | -129.8 | 127.1 | NA | NA | NA | |||||||||||||
6nk0 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | VAL | A:145 | A:165 | 73.0 | 0.471 | E | -126.0 | 127.2 | 73.0 | 0.471 | 0.0 |
GOL HOH |
4.285 2.084 |
O H |
O1 O |
||
VAL | B:145 | B:165 | 68.0 | 0.439 | E | -126.3 | 127.1 | NA | NA | NA | |||||||||||||
6nk1 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | VAL | A:145 | A:165 | 82.0 | 0.529 | E | -122.7 | 127.1 | 82.0 | 0.529 | 0.0 |
HOH |
2.101 |
H |
O |
||
VAL | B:145 | B:165 | 81.0 | 0.523 | E | -124.2 | 125.2 | NA | NA | NA | |||||||||||||
6nk2 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | VAL | A:145 | A:165 | 73.0 | 0.471 | E | -127.9 | 126.2 | 73.0 | 0.471 | 0.0 |
HOH |
2.275 |
H |
O |
||
VAL | B:145 | B:165 | 71.0 | 0.458 | E | -126.2 | 125.7 | NA | NA | NA | |||||||||||||
6nkp | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | VAL | A:145 | A:165 | 79.0 | 0.51 | E | -131.8 | 121.9 | 79.0 | 0.51 | 0.0 |
HOH |
2.013 |
H |
O |
||
VAL | B:145 | B:165 | 73.0 | 0.471 | E | -133.9 | 121.8 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29317-f1 | 1 | P29317 | 100.0 | 0.0 | VAL | A:165 | A:165 | 73.0 | 0.471 | E | -131.7 | 112.5 |