Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 16475203 . C A CCDS169.1:NM_004431.3:c.493Gtg>Ttg_NP_004422.2:p.165V>L Homo sapiens EPH receptor A2 (EPHA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3fl7 1 Q8N3Z2 99.42 0.0 X-RAY
 2009-01-27 VAL A:170 A:165 70.0 0.452 E -123.7 138.2 70.0 0.452 0.0 NA
HOH
 5.098
2.809
 O
N
 NA
O
2x10 1 P29317 100.0 0.0 X-RAY
 2010-03-16 VAL A:167 A:165 64.0 0.413 E -109.2 136.0 64.0 0.413 0.0
2x11 1 P29317 100.0 0.0 X-RAY
 2010-03-16 VAL A:167 A:165 78.0 0.503 E -123.6 122.5 78.0 0.503 0.0
3mx0 1 P29317 100.0 0.0 X-RAY
 2010-06-30 VAL A:139 A:165 81.0 0.523 E -108.7 120.2 81.0 0.523 0.0
VAL C:139 C:165 71.0 0.458 E -82.1 140.7 NA NA NA
3mbw 1 P29317 99.03 0.0 X-RAY
 2010-06-09 VAL A:169 A:165 84.0 0.542 E -116.8 121.6 84.0 0.542 0.0 UNX
HOH
 5.521
3.909
 O
O
 UNK
O
3czu 1 P29317 98.37 2e-127 X-RAY
 2008-08-12 VAL A:170 A:165 76.0 0.49 E -124.5 127.3 76.0 0.49 0.0 HOH
 2.955
 N
 O
3c8x 1 P29317 98.37 2e-127 X-RAY
 2008-03-25 VAL A:169 A:165 88.0 0.568 E -128.3 122.8 77.0 0.497 0.071 A:P29317:0.071
 HOH
 3.061
 N
 O
3skj 3 P29317 98.37 2e-127 X-RAY
 2011-08-31 VAL E:169 E:141 74.0 0.477 E -123.0 127.6 74.0 0.477 0.0 HOH
 4.238
 CG2
 O
VAL F:169 F:141 93.0 0.6 E -122.0 137.3 NA NA NA
7czf 1 P29317 98.36 4e-127 X-RAY
 2020-10-21 VAL A:138 A:165 41.0 0.265 E -125.0 126.9 41.0 0.265 0.0
VAL D:138 D:165 48.0 0.31 E -114.9 133.0 NA NA NA
7b7n 1 P29317 99.45 7e-127 X-RAY
 2020-12-30 VAL A:143 E:165 73.0 0.471 E -114.1 112.9 73.0 0.471 0.0 HOH
 6.479
 CG1
 O
6rw2 1 P29317 96.7 6e-124 X-RAY
 2020-04-08 VAL A:157 A:165 76.0 0.49 E -123.5 117.7 76.0 0.49 0.0 HOH
 3.019
 N
 O
7cze 3 P29317 100.0 1e-123 X-RAY
 2020-10-21 VAL I:140 I:165 81.0 0.523 E -130.9 109.5 81.0 0.523 0.0
VAL J:140 J:165 78.0 0.503 E -129.1 109.5 NA NA NA
VAL K:140 K:165 78.0 0.503 E -131.0 109.3 NA NA NA
VAL L:140 L:165 79.0 0.51 E -131.0 109.2 NA NA NA
3hei 1 P29317 100.0 7e-123 X-RAY
 2009-06-30 VAL A:138 A:138 73.0 0.471 E -126.7 130.0 73.0 0.471 0.0 HOH
 2.581
 O
 O
VAL C:138 C:138 71.0 0.458 E -127.1 127.8 NA NA NA
VAL E:138 E:138 75.0 0.484 E -131.7 129.4 NA NA NA
VAL G:138 G:138 68.0 0.439 E -126.1 124.7 NA NA NA
VAL I:138 I:138 75.0 0.484 E -125.8 118.5 NA NA NA
VAL K:138 K:138 71.0 0.458 E -133.0 121.9 NA NA NA
VAL M:138 M:138 72.0 0.465 E -126.5 130.3 NA NA NA
VAL O:138 O:138 79.0 0.51 E -118.1 131.8 NA NA NA
3hpn 1 P29317 100.0 7e-123 X-RAY
 2009-06-30 VAL A:138 A:138 74.0 0.477 E -122.4 124.6 74.0 0.477 0.0 HOH
 2.490
 O
 O
VAL B:138 B:138 75.0 0.484 E -115.7 129.3 NA NA NA
VAL C:138 C:138 75.0 0.484 E -119.5 129.9 NA NA NA
VAL D:138 D:138 74.0 0.477 E -121.2 126.6 NA NA NA
VAL E:138 E:138 74.0 0.477 E -119.0 128.8 NA NA NA
VAL F:138 F:138 76.0 0.49 E -122.4 122.7 NA NA NA
6b9l 1 P29317 100.0 9e-123 X-RAY
 2018-10-17 VAL A:160 A:165 71.0 0.458 E -117.6 120.0 71.0 0.458 0.0
VAL B:160 B:165 72.0 0.465 E -129.1 117.4 72.0 0.465 0.0
VAL C:160 C:165 69.0 0.445 E -121.2 126.8 69.0 0.445 0.0
VAL D:160 D:165 70.0 0.452 E -130.9 124.9 70.0 0.452 0.0
6njz 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 VAL A:145 A:165 70.0 0.452 E -129.1 127.3 70.0 0.452 0.0 GOL
GOL
HOH
 7.757
9.199
2.095
 HG12
HG12
H
 HO3
H31
O
VAL B:145 B:165 73.0 0.471 E -129.8 127.1 NA NA NA
6nk0 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 VAL A:145 A:165 73.0 0.471 E -126.0 127.2 73.0 0.471 0.0 GOL
HOH
 4.285
2.084
 O
H
 O1
O
VAL B:145 B:165 68.0 0.439 E -126.3 127.1 NA NA NA
6nk1 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 VAL A:145 A:165 82.0 0.529 E -122.7 127.1 82.0 0.529 0.0 HOH
 2.101
 H
 O
VAL B:145 B:165 81.0 0.523 E -124.2 125.2 NA NA NA
6nk2 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 VAL A:145 A:165 73.0 0.471 E -127.9 126.2 73.0 0.471 0.0 HOH
 2.275
 H
 O
VAL B:145 B:165 71.0 0.458 E -126.2 125.7 NA NA NA
6nkp 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 VAL A:145 A:165 79.0 0.51 E -131.8 121.9 79.0 0.51 0.0 HOH
 2.013
 H
 O
VAL B:145 B:165 73.0 0.471 E -133.9 121.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p29317-f1 1 P29317 100.0 0.0 VAL A:165 A:165 73.0 0.471 E -131.7 112.5