Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 16475386 | . | C | A | CCDS169.1:NM_004431.3:c.310Gac>Tac_NP_004422.2:p.104D>Y | Homo sapiens EPH receptor A2 (EPHA2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3fl7 | 1 | Q8N3Z2 | 99.42 | 0.0 |
X-RAY |
2009-01-27 | ASP | A:109 | A:104 | 46.0 | 0.307 | -64.9 | 126.3 | 35.0 | 0.233 | 0.074 |
A:Q8N3Z2:0.073 |
HOH |
7.074 |
N |
O |
||
2x10 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-03-16 | ASP | A:106 | A:104 | 37.0 | 0.247 | -76.4 | 125.3 | 37.0 | 0.247 | 0.0 | |||||||
2x11 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-03-16 | ASP | A:106 | A:104 | 25.0 | 0.167 | -56.7 | 121.7 | 25.0 | 0.167 | 0.0 | |||||||
3mx0 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-06-30 | ASP | A:78 | A:104 | 29.0 | 0.193 | -62.9 | 148.8 | 29.0 | 0.193 | 0.0 | |||||||
ASP | C:78 | C:104 | 25.0 | 0.167 | -45.4 | 128.3 | NA | NA | NA | ||||||||||||||
3mbw | 1 | P29317 | 99.03 | 0.0 |
X-RAY |
2010-06-09 | ASP | A:108 | A:104 | 28.0 | 0.187 | -60.8 | 142.5 | 28.0 | 0.187 | 0.0 |
HOH |
4.586 |
OD1 |
O |
|||
3czu | 1 | P29317 | 98.37 | 2e-127 |
X-RAY |
2008-08-12 | ASP | A:109 | A:104 | 26.0 | 0.173 | -52.4 | 115.7 | 26.0 | 0.173 | 0.0 |
HOH |
8.198 |
CG |
O |
|||
3c8x | 1 | P29317 | 98.37 | 2e-127 |
X-RAY |
2008-03-25 | ASP | A:108 | A:104 | 46.0 | 0.307 | -67.3 | 142.8 | 46.0 | 0.307 | 0.0 |
HOH |
3.260 |
N |
O |
|||
3skj | 3 | P29317 | 98.37 | 2e-127 |
X-RAY |
2011-08-31 | ASP | E:108 | E:80 | 23.0 | 0.153 | -63.9 | 119.7 | 23.0 | 0.153 | 0.0 |
HOH |
4.243 |
N |
O |
|||
ASP | F:108 | F:80 | 43.0 | 0.287 | -66.9 | 126.0 | NA | NA | NA | ||||||||||||||
7czf | 1 | P29317 | 98.36 | 4e-127 |
X-RAY |
2020-10-21 | ASP | A:77 | A:104 | 64.0 | 0.427 | -67.1 | 162.9 | 64.0 | 0.427 | 0.0 | |||||||
ASP | D:77 | D:104 | 69.0 | 0.46 | -67.1 | 149.2 | NA | NA | NA | ||||||||||||||
7b7n | 1 | P29317 | 99.45 | 7e-127 |
X-RAY |
2020-12-30 | ASP | A:82 | E:104 | 86.0 | 0.573 | -58.0 | 128.8 | 86.0 | 0.573 | 0.0 |
CL HOH |
2.893 5.642 |
N CB |
CL O |
|||
6rw2 | 1 | P29317 | 96.7 | 6e-124 |
X-RAY |
2020-04-08 | ASP | A:96 | A:104 | 35.0 | 0.233 | -57.1 | 121.9 | 35.0 | 0.233 | 0.0 |
GOL HOH |
9.499 3.162 |
C OD2 |
O2 O |
|||
7cze | 3 | P29317 | 100.0 | 1e-123 |
X-RAY |
2020-10-21 | ASP | I:79 | I:104 | 39.0 | 0.26 | -70.9 | 159.2 | 39.0 | 0.26 | 0.0 | |||||||
ASP | J:79 | J:104 | 40.0 | 0.267 | -70.9 | 159.2 | NA | NA | NA | ||||||||||||||
ASP | K:79 | K:104 | 43.0 | 0.287 | -70.8 | 159.0 | NA | NA | NA | ||||||||||||||
ASP | L:79 | L:104 | 43.0 | 0.287 | -70.9 | 159.0 | NA | NA | NA | ||||||||||||||
3hei | 1 | P29317 | 100.0 | 7e-123 |
X-RAY |
2009-06-30 | ASP | A:77 | A:77 | 30.0 | 0.2 | -60.7 | 132.4 | 30.0 | 0.2 | 0.0 |
HOH |
2.621 |
OD1 |
O |
|||
ASP | C:77 | C:77 | 30.0 | 0.2 | -66.7 | 132.0 | NA | NA | NA | ||||||||||||||
ASP | E:77 | E:77 | 34.0 | 0.227 | -60.2 | 125.3 | NA | NA | NA | ||||||||||||||
ASP | G:77 | G:77 | 32.0 | 0.213 | -58.6 | 133.3 | NA | NA | NA | ||||||||||||||
ASP | I:77 | I:77 | 33.0 | 0.22 | -50.7 | 128.7 | NA | NA | NA | ||||||||||||||
ASP | K:77 | K:77 | 31.0 | 0.207 | -62.6 | 124.8 | NA | NA | NA | ||||||||||||||
ASP | M:77 | M:77 | 34.0 | 0.227 | -67.7 | 125.5 | NA | NA | NA | ||||||||||||||
ASP | O:77 | O:77 | 23.0 | 0.153 | -61.2 | 128.2 | NA | NA | NA | ||||||||||||||
3hpn | 1 | P29317 | 100.0 | 7e-123 |
X-RAY |
2009-06-30 | ASP | A:77 | A:77 | 24.0 | 0.16 | -52.1 | 128.1 | 24.0 | 0.16 | 0.0 |
HOH |
2.797 |
OD2 |
O |
|||
ASP | B:77 | B:77 | 25.0 | 0.167 | -50.9 | 124.1 | NA | NA | NA | ||||||||||||||
ASP | C:77 | C:77 | 22.0 | 0.147 | -57.9 | 129.6 | NA | NA | NA | ||||||||||||||
ASP | D:77 | D:77 | 23.0 | 0.153 | -56.9 | 129.9 | NA | NA | NA | ||||||||||||||
ASP | E:77 | E:77 | 25.0 | 0.167 | -56.5 | 128.3 | NA | NA | NA | ||||||||||||||
ASP | F:77 | F:77 | 25.0 | 0.167 | -60.8 | 126.3 | NA | NA | NA | ||||||||||||||
6b9l | 1 | P29317 | 100.0 | 9e-123 |
X-RAY |
2018-10-17 | ASP | A:99 | A:104 | 20.0 | 0.133 | -60.5 | 129.2 | 20.0 | 0.133 | 0.0 | |||||||
ASP | B:99 | B:104 | 16.0 | 0.107 | -59.3 | 128.5 | 16.0 | 0.107 | 0.0 | ||||||||||||||
ASP | C:99 | C:104 | 21.0 | 0.14 | -60.4 | 125.3 | 21.0 | 0.14 | 0.0 | ||||||||||||||
ASP | D:99 | D:104 | 22.0 | 0.147 | -69.9 | 132.3 | 22.0 | 0.147 | 0.0 | ||||||||||||||
6njz | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ASP | A:84 | A:104 | 21.0 | 0.14 | -54.4 | 128.6 | 21.0 | 0.14 | 0.0 |
HOH |
3.558 |
H |
O |
|||
ASP | B:84 | B:104 | 24.0 | 0.16 | -54.2 | 127.7 | NA | NA | NA | ||||||||||||||
6nk0 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ASP | A:84 | A:104 | 21.0 | 0.14 | -55.0 | 127.9 | 21.0 | 0.14 | 0.0 |
HOH |
2.554 |
OD2 |
O |
|||
ASP | B:84 | B:104 | 29.0 | 0.193 | -58.1 | 127.2 | NA | NA | NA | ||||||||||||||
6nk1 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ASP | A:84 | A:104 | 20.0 | 0.133 | -59.0 | 128.7 | 20.0 | 0.133 | 0.0 |
HOH |
2.664 |
OD2 |
O |
|||
ASP | B:84 | B:104 | 24.0 | 0.16 | -56.1 | 126.2 | NA | NA | NA | ||||||||||||||
6nk2 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ASP | A:84 | A:104 | 24.0 | 0.16 | -58.6 | 129.0 | 24.0 | 0.16 | 0.0 |
HOH |
3.206 |
HB3 |
O |
|||
ASP | B:84 | B:104 | 19.0 | 0.127 | -56.7 | 127.4 | NA | NA | NA | ||||||||||||||
6nkp | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ASP | A:84 | A:104 | 21.0 | 0.14 | -53.7 | 126.1 | 21.0 | 0.14 | 0.0 |
HOH |
2.608 |
OD2 |
O |
|||
ASP | B:84 | B:104 | 30.0 | 0.2 | -53.7 | 128.8 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29317-f1 | 1 | P29317 | 100.0 | 0.0 | ASP | A:104 | A:104 | 24.0 | 0.16 | -52.7 | 127.3 |