Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 16475419 | . | G | A | CCDS169.1:NM_004431.3:c.277Cgt>Tgt_NP_004422.2:p.93R>C | Homo sapiens EPH receptor A2 (EPHA2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3fl7 | 1 | Q8N3Z2 | 99.42 | 0.0 |
X-RAY |
2009-01-27 | ARG | A:98 | A:93 | 57.0 | 0.253 | S | -108.4 | 128.5 | 57.0 | 0.253 | 0.0 |
CL HOH |
3.733 3.306 |
NH1 N |
CL O |
||
2x10 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-03-16 | ARG | A:95 | A:93 | 51.0 | 0.227 | S | -127.9 | 121.8 | 51.0 | 0.227 | 0.0 |
CL |
3.364 |
NH1 |
CL |
||
2x11 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-03-16 | ARG | A:95 | A:93 | 73.0 | 0.324 | S | -115.3 | 118.3 | 73.0 | 0.324 | 0.0 | ||||||
3mx0 | 1 | P29317 | 100.0 | 0.0 |
X-RAY |
2010-06-30 | ARG | A:67 | A:93 | 55.0 | 0.244 | S | -129.8 | 115.6 | 55.0 | 0.244 | 0.0 | ||||||
ARG | C:67 | C:93 | 59.0 | 0.262 | S | -134.5 | 118.5 | NA | NA | NA | |||||||||||||
3mbw | 1 | P29317 | 99.03 | 0.0 |
X-RAY |
2010-06-09 | ARG | A:97 | A:93 | 59.0 | 0.262 | S | -121.4 | 118.9 | 59.0 | 0.262 | 0.0 |
HOH |
8.034 |
NH1 |
O |
||
3czu | 1 | P29317 | 98.37 | 2e-127 |
X-RAY |
2008-08-12 | ARG | A:98 | A:93 | 110.0 | 0.489 | S | -109.1 | 124.4 | 110.0 | 0.489 | 0.0 |
HOH |
3.096 |
NH2 |
O |
||
3c8x | 1 | P29317 | 98.37 | 2e-127 |
X-RAY |
2008-03-25 | ARG | A:97 | A:93 | 111.0 | 0.493 | S | -113.4 | 123.5 | 111.0 | 0.493 | 0.0 |
HOH |
2.608 |
O |
O |
||
3skj | 3 | P29317 | 98.37 | 2e-127 |
X-RAY |
2011-08-31 | ARG | E:97 | E:69 | 117.0 | 0.52 | S | -128.9 | 131.5 | 117.0 | 0.52 | 0.0 | ||||||
ARG | F:97 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
7czf | 1 | P29317 | 98.36 | 4e-127 |
X-RAY |
2020-10-21 | ARG | A:66 | A:93 | 122.0 | 0.542 | S | -125.1 | 121.0 | 122.0 | 0.542 | 0.0 | ||||||
ARG | D:66 | D:93 | 121.0 | 0.538 | S | -127.2 | 119.1 | NA | NA | NA | |||||||||||||
7b7n | 1 | P29317 | 99.45 | 7e-127 |
X-RAY |
2020-12-30 | ARG | A:71 | E:93 | 129.0 | 0.573 | S | -121.8 | 113.4 | 129.0 | 0.573 | 0.0 | ||||||
6rw2 | 1 | P29317 | 96.7 | 6e-124 |
X-RAY |
2020-04-08 | ARG | A:85 | A:93 | 114.0 | 0.507 | S | -117.1 | 129.2 | 114.0 | 0.507 | 0.0 |
HOH |
2.822 |
O |
O |
||
7cze | 3 | P29317 | 100.0 | 1e-123 |
X-RAY |
2020-10-21 | ARG | I:68 | I:93 | 94.0 | 0.418 | S | -123.3 | 121.0 | 94.0 | 0.418 | 0.0 | ||||||
ARG | J:68 | J:93 | 93.0 | 0.413 | S | -123.2 | 121.0 | NA | NA | NA | |||||||||||||
ARG | K:68 | K:93 | 95.0 | 0.422 | S | -123.3 | 121.3 | NA | NA | NA | |||||||||||||
ARG | L:68 | L:93 | 92.0 | 0.409 | S | -123.1 | 121.1 | NA | NA | NA | |||||||||||||
3hei | 1 | P29317 | 100.0 | 7e-123 |
X-RAY |
2009-06-30 | ARG | A:66 | A:66 | 120.0 | 0.533 | S | -118.6 | 127.8 | 120.0 | 0.533 | 0.0 |
HOH |
2.698 |
NH1 |
O |
||
ARG | C:66 | C:66 | 112.0 | 0.498 | S | -120.1 | 131.1 | NA | NA | NA | |||||||||||||
ARG | E:66 | E:66 | 117.0 | 0.52 | S | -123.2 | 121.6 | NA | NA | NA | |||||||||||||
ARG | G:66 | G:66 | 113.0 | 0.502 | S | -121.2 | 127.5 | NA | NA | NA | |||||||||||||
ARG | I:66 | I:66 | 117.0 | 0.52 | S | -120.7 | 136.6 | NA | NA | NA | |||||||||||||
ARG | K:66 | K:66 | 111.0 | 0.493 | S | -117.2 | 135.3 | NA | NA | NA | |||||||||||||
ARG | M:66 | M:66 | 117.0 | 0.52 | S | -121.6 | 128.3 | NA | NA | NA | |||||||||||||
ARG | O:66 | O:66 | 117.0 | 0.52 | S | -117.0 | 121.4 | NA | NA | NA | |||||||||||||
3hpn | 1 | P29317 | 100.0 | 7e-123 |
X-RAY |
2009-06-30 | ARG | A:66 | A:66 | 115.0 | 0.511 | S | -117.3 | 120.1 | 115.0 | 0.511 | 0.0 |
HOH |
2.299 |
O |
O |
||
ARG | B:66 | B:66 | 118.0 | 0.524 | S | -115.8 | 125.7 | NA | NA | NA | |||||||||||||
ARG | C:66 | C:66 | 117.0 | 0.52 | S | -122.6 | 126.6 | NA | NA | NA | |||||||||||||
ARG | D:66 | D:66 | 116.0 | 0.516 | S | -119.8 | 123.6 | NA | NA | NA | |||||||||||||
ARG | E:66 | E:66 | 121.0 | 0.538 | S | -119.2 | 128.4 | NA | NA | NA | |||||||||||||
ARG | F:66 | F:66 | 120.0 | 0.533 | S | -116.4 | 120.5 | NA | NA | NA | |||||||||||||
6b9l | 1 | P29317 | 100.0 | 9e-123 |
X-RAY |
2018-10-17 | ARG | A:88 | A:93 | 110.0 | 0.489 | S | -115.3 | 164.5 | 94.0 | 0.418 | 0.071 |
I:None:0.071 |
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ARG | B:88 | B:93 | 158.0 | 0.702 | S | -128.4 | 98.5 | 158.0 | 0.702 | 0.0 | |||||||||||||
ARG | C:88 | C:93 | 122.0 | 0.542 | S | -110.0 | 111.4 | 122.0 | 0.542 | 0.0 | |||||||||||||
ARG | D:88 | D:93 | 134.0 | 0.596 | S | -121.8 | 130.4 | 134.0 | 0.596 | 0.0 | |||||||||||||
6njz | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ARG | A:73 | A:93 | 113.0 | 0.502 | S | -97.1 | 128.7 | 113.0 | 0.502 | 0.0 |
GOL GOL HOH |
3.711 7.061 1.946 |
HH21 HG2 HH12 |
HO1 H32 O |
||
ARG | B:73 | B:93 | 110.0 | 0.489 | S | -109.6 | 131.7 | NA | NA | NA | |||||||||||||
6nk0 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ARG | A:73 | A:93 | 108.0 | 0.48 | S | -127.6 | 134.9 | 108.0 | 0.48 | 0.0 |
HOH |
2.374 |
HH12 |
O |
||
ARG | B:73 | B:93 | 106.0 | 0.471 | S | -127.7 | 134.0 | NA | NA | NA | |||||||||||||
6nk1 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ARG | A:73 | A:93 | 147.0 | 0.653 | S | -132.5 | 118.8 | 147.0 | 0.653 | 0.0 |
HOH |
2.493 |
O |
O |
||
ARG | B:73 | B:93 | 167.0 | 0.742 | S | -115.1 | 126.6 | NA | NA | NA | |||||||||||||
6nk2 | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ARG | A:73 | A:93 | 108.0 | 0.48 | S | -133.3 | 136.7 | 108.0 | 0.48 | 0.0 |
HOH |
2.444 |
H |
O |
||
ARG | B:73 | B:93 | 113.0 | 0.502 | S | -128.6 | 133.0 | NA | NA | NA | |||||||||||||
6nkp | 1 | P29317 | 98.32 | 3e-122 |
X-RAY |
2019-05-01 | ARG | A:73 | A:93 | 110.0 | 0.489 | S | -118.4 | 128.7 | 110.0 | 0.489 | 0.0 |
HOH |
2.189 |
H |
O |
||
ARG | B:73 | B:93 | 130.0 | 0.578 | S | -95.5 | 130.2 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29317-f1 | 1 | P29317 | 100.0 | 0.0 | ARG | A:93 | A:93 | 47.0 | 0.209 | S | -111.7 | 129.4 |