Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 16477425 . T A CCDS169.1:NM_004431.3:c.119gAg>gTg_NP_004422.2:p.40E>V Homo sapiens EPH receptor A2 (EPHA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3fl7 1 Q8N3Z2 99.42 0.0 X-RAY
 2009-01-27 GLU A:45 A:40 177.0 0.932 -68.2 -7.6 177.0 0.932 0.0 CL
 8.325
 OE1
 CL
2x10 1 P29317 100.0 0.0 X-RAY
 2010-03-16 GLU A:42 NA:NA DO NA DO DO DO NA NA NA
2x11 1 P29317 100.0 0.0 X-RAY
 2010-03-16 GLU A:42 A:40 170.0 0.895 -104.0 3.0 149.0 0.784 0.111 B:P52803:0.111
3mx0 1 P29317 100.0 0.0 X-RAY
 2010-06-30 GLU A:14 A:40 164.0 0.863 -139.4 5.2 159.0 0.837 0.026 B:P52803:0.026
GLU C:14 C:40 171.0 0.9 -91.7 17.7 NA NA NA
3mbw 1 P29317 99.03 0.0 X-RAY
 2010-06-09 GLU A:44 A:40 187.0 0.984 -57.1 -19.8 57.0 0.3 0.684 B:P20827:0.232
A:P29317:0.453
 HOH
 3.863
 N
 O
3czu 1 P29317 98.37 2e-127 X-RAY
 2008-08-12 GLU A:45 A:40 172.0 0.905 -93.0 4.7 113.0 0.595 0.31 B:P20827:0.311
 HOH
 3.516
 N
 O
3c8x 1 P29317 98.37 2e-127 X-RAY
 2008-03-25 GLU A:44 NA:NA DO NA DO DO DO NA NA NA
3skj 3 P29317 98.37 2e-127 X-RAY
 2011-08-31 GLU E:44 E:16 174.0 0.916 -81.8 -7.6 174.0 0.916 0.0 HOH
 9.626
 C
 O
GLU F:44 NA:NA DO NA DO DO DO NA NA NA
7czf 1 P29317 98.36 4e-127 X-RAY
 2020-10-21 GLU A:13 A:40 174.0 0.916 -71.0 -23.1 174.0 0.916 0.0
GLU D:13 D:40 177.0 0.932 -67.1 -19.1 NA NA NA
7b7n 1 P29317 99.45 7e-127 X-RAY
 2020-12-30 GLU A:18 E:40 185.0 0.974 -92.6 15.0 185.0 0.974 0.0 CL
CL
HOH
 4.444
8.326
4.272
 C
N
N
 CL
CL
O
6rw2 1 P29317 96.7 6e-124 X-RAY
 2020-04-08 GLU A:32 A:40 178.0 0.937 -112.3 13.6 178.0 0.937 0.0 HOH
 6.828
 N
 O
7cze 3 P29317 100.0 1e-123 X-RAY
 2020-10-21 GLU I:15 I:40 25.0 0.132 -41.9 -57.7 11.0 0.058 0.074 B:P03212:0.074
 NAG
 8.429
 OE2
 O6
GLU J:15 J:40 26.0 0.137 -41.6 -58.4 NA NA NA
GLU K:15 K:40 26.0 0.137 -42.3 -57.5 NA NA NA
GLU L:15 L:40 26.0 0.137 -43.7 -59.9 NA NA NA
3hei 1 P29317 100.0 7e-123 X-RAY
 2009-06-30 GLU A:13 A:13 181.0 0.953 -79.8 -7.9 153.0 0.805 0.148 B:P20827:0.147
 HOH
 2.433
 OE1
 O
GLU C:13 C:13 183.0 0.963 -81.8 -4.6 NA NA NA
GLU E:13 E:13 168.0 0.884 -93.7 -10.2 NA NA NA
GLU G:13 G:13 172.0 0.905 -96.1 -9.9 NA NA NA
GLU I:13 I:13 170.0 0.895 -81.7 -16.2 NA NA NA
GLU K:13 K:13 183.0 0.963 -81.9 -1.1 NA NA NA
GLU M:13 M:13 180.0 0.947 -88.4 -9.1 NA NA NA
GLU O:13 O:13 168.0 0.884 -89.2 -15.8 NA NA NA
3hpn 1 P29317 100.0 7e-123 X-RAY
 2009-06-30 GLU A:13 A:13 27.0 0.142 T -79.9 -9.8 27.0 0.142 0.0 HOH
 2.296
 OE2
 O
GLU B:13 B:13 28.0 0.147 T -75.7 -12.1 NA NA NA
GLU C:13 C:13 30.0 0.158 T -80.4 -8.9 NA NA NA
GLU D:13 D:13 27.0 0.142 T -77.2 -13.0 NA NA NA
GLU E:13 E:13 27.0 0.142 T -80.5 -8.1 NA NA NA
GLU F:13 F:13 28.0 0.147 T -77.1 -10.4 NA NA NA
6b9l 1 P29317 100.0 9e-123 X-RAY
 2018-10-17 GLU A:35 A:40 167.0 0.879 -106.5 -0.2 56.0 0.295 0.584 E:None:0.168
B:P29317:0.468
GLU B:35 B:40 165.0 0.868 -74.0 -12.2 54.0 0.284 0.584 A:P29317:0.463
F:None:0.189
GLU C:35 C:40 158.0 0.832 -120.3 66.3 64.0 0.337 0.495 D:P29317:0.358
G:None:0.158
GLU D:35 D:40 86.0 NA -121.4 3.9 9.0 NA NA C:P29317:NA
H:None:NA
6njz 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 GLU A:20 A:40 171.0 0.9 -91.4 1.6 165.0 0.868 0.032 C:None:0.032
 BTN
HOH
 9.405
8.121
 OE2
HB2
 O11
O
GLU B:20 B:40 164.0 0.863 -91.1 -8.6 NA NA NA
6nk0 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 GLU A:20 NA:NA DO NA DO DO DO NA NA NA
GLU B:20 B:40 166.0 0.874 -101.0 94.2 NA NA NA
6nk1 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 GLU A:20 A:40 162.0 0.853 -101.9 1.4 122.0 0.642 0.211 C:None:0.211
 HOH
 2.516
 OE2
 O
GLU B:20 B:40 171.0 0.9 -93.3 -5.9 NA NA NA
6nk2 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 GLU A:20 A:40 167.0 0.879 -99.1 -5.1 151.0 0.795 0.084 C:None:0.084
 HOH
 2.933
 HG3
 O
GLU B:20 B:40 170.0 0.895 -96.1 -11.0 NA NA NA
6nkp 1 P29317 98.32 3e-122 X-RAY
 2019-05-01 GLU A:20 A:40 169.0 0.889 -98.8 -15.4 157.0 0.826 0.063 C:None:0.063
 BTN
HOH
 8.483
2.955
 O
H
 O11
O
GLU B:20 B:40 163.0 0.858 -100.3 -17.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p29317-f1 1 P29317 100.0 0.0 GLU A:40 A:40 159.0 0.837 -83.4 -15.0