Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 165386371 | . | C | A | CCDS1248.1:NM_006917.4:c.529Gat>Tat_NP_008848.1:p.177D>Y | Homo sapiens retinoid X receptor gamma (RXRG), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4nqa | 1 | P19793 | 83.01 | 0.0 |
X-RAY |
2014-02-26 | ASP | A:76 | A:173 | 96.0 | 0.64 | S | -136.1 | -63.0 | 96.0 | 0.64 | 0.0 |
ZN |
4.660 |
CB |
ZN |
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| ASP | G:76 | H:173 | 131.0 | 0.873 | S | -75.8 | -73.8 | NA | NA | NA | |||||||||||||
| 5uan | 1 | P19793 | 83.01 | 0.0 |
X-RAY |
2017-10-18 | ASP | A:76 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 1ynw | 4 | P19793 | 83.84 | 5e-61 |
X-RAY |
2005-02-15 | ASP | D:44 | B:273 | 132.0 | 0.88 | S | -139.2 | -122.1 | 132.0 | 0.88 | 0.0 |
ZN |
4.519 |
N |
ZN |
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| 1dsz | 4 | P19793 | 94.05 | 6e-58 |
X-RAY |
2000-07-10 | ASP | D:46 | B:1273 | 56.0 | NA | S | -123.7 | -119.8 | 56.0 | NA | NA |
ZN HOH |
4.973 3.299 |
CB CB |
ZN O |
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| 1by4 | 3 | P19793 | 93.9 | 2e-56 |
X-RAY |
2000-01-12 | ASP | E:46 | A:1173 | 121.0 | 0.807 | S | -138.7 | -63.8 | 121.0 | 0.807 | 0.0 |
ZN HOH |
5.400 6.458 |
N OD1 |
ZN O |
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| ASP | F:46 | B:1273 | 130.0 | 0.867 | S | -147.6 | -62.7 | 130.0 | 0.867 | 0.0 |
ZN HOH |
4.873 9.288 |
CB C |
ZN O |
|||||||||
| ASP | G:46 | C:2173 | 124.0 | 0.827 | S | -99.0 | -38.1 | NA | NA | NA | |||||||||||||
| ASP | H:46 | D:2273 | 115.0 | 0.767 | S | -122.0 | -123.2 | NA | NA | NA | |||||||||||||
| 4cn2 | 3 | P19793 | 93.9 | 2e-56 |
X-RAY |
2015-02-18 | ASP | C:48 | C:173 | 99.0 | 0.66 | S | -108.2 | -129.9 | 92.0 | 0.613 | 0.047 |
D:P19793:0.047 |
ZN HOH |
4.849 3.238 |
CB CB |
ZN O |
|
| ASP | D:48 | D:173 | 110.0 | 0.733 | S | -120.8 | -106.4 | 110.0 | 0.733 | 0.0 |
ZN CL CL HOH |
4.026 9.332 9.975 4.253 |
OD1 N N N |
ZN CL CL O |
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| 4cn3 | 1 | P19793 | 93.9 | 2e-56 |
X-RAY |
2015-02-18 | ASP | A:48 | A:173 | 119.0 | 0.793 | S | -104.3 | -124.4 | NA | NA | NA | ||||||
| ASP | B:48 | B:173 | 84.0 | 0.56 | S | -106.1 | -105.7 | 84.0 | 0.56 | 0.0 |
ZN HOH |
4.780 3.398 |
N CB |
ZN O |
|||||||||
| ASP | C:48 | C:173 | 111.0 | 0.74 | S | -102.0 | -123.2 | 111.0 | 0.74 | 0.0 |
ZN HOH |
5.009 2.574 |
N O |
ZN O |
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| 4cn5 | 1 | P19793 | 93.9 | 2e-56 |
X-RAY |
2015-02-18 | ASP | A:48 | A:173 | 116.0 | 0.773 | S | -116.2 | -128.1 | 116.0 | 0.773 | 0.0 |
ZN CL HOH |
5.044 4.246 3.071 |
N N O |
ZN CL O |
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| ASP | B:48 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4cn7 | 1 | P19793 | 93.9 | 2e-56 |
X-RAY |
2015-02-18 | ASP | A:48 | A:173 | 122.0 | 0.813 | S | -116.0 | -117.0 | NA | NA | NA | ||||||
| ASP | B:48 | B:173 | 123.0 | 0.82 | S | -114.8 | -137.3 | NA | NA | NA | |||||||||||||
| ASP | E:48 | E:173 | 116.0 | 0.773 | S | -114.7 | -136.8 | 116.0 | 0.773 | 0.0 |
ZN HOH |
5.012 7.871 |
N N |
ZN O |
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| ASP | F:48 | F:173 | 111.0 | 0.74 | S | -114.2 | -136.5 | 111.0 | 0.74 | 0.0 |
ZN HOH |
4.890 2.700 |
CB OD1 |
ZN O |
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| 6fbq | 1 | P19793 | 93.9 | 2e-56 |
X-RAY |
2018-12-05 | ASP | A:48 | A:173 | 103.0 | 0.687 | S | -105.1 | -119.8 | 100.0 | 0.667 | 0.02 |
B:P19793:0.02 |
ZN HOH |
4.241 2.737 |
H OD2 |
ZN O |
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| ASP | B:48 | B:173 | 116.0 | 0.773 | S | -97.8 | -124.3 | 116.0 | 0.773 | 0.0 |
ZN HOH |
4.075 4.213 |
HB2 O |
ZN O |
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| 6fbr | 1 | P19793 | 93.9 | 2e-56 |
X-RAY |
2018-12-05 | ASP | A:48 | A:173 | 103.0 | 0.687 | -106.6 | 109.0 | 90.0 | 0.6 | 0.087 |
B:P19793:0.087 |
HOH |
7.229 |
OD1 |
O |
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| ASP | B:48 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6xwg | 3 | P19793 | 93.9 | 2e-56 |
X-RAY |
2020-09-09 | ASP | C:48 | C:173 | 127.0 | 0.847 | S | -97.8 | -139.4 | 89.0 | 0.593 | 0.254 |
D:P10276:0.253 |
ZN HOH |
5.087 2.694 |
N OD1 |
ZN O |
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| 6xwh | 3 | P19793 | 93.9 | 2e-56 |
X-RAY |
2020-09-09 | ASP | C:48 | C:173 | 90.0 | 0.6 | S | -97.8 | -156.7 | 90.0 | 0.6 | 0.0 |
ZN HOH |
4.948 8.111 |
N N |
ZN O |
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| ASP | D:48 | D:173 | 96.0 | 0.64 | S | -117.6 | -130.7 | 96.0 | 0.64 | 0.0 |
ZN HOH |
4.391 3.088 |
OD2 O |
ZN O |
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| 4cn3 | 2 | P19793 | 92.68 | 1e-55 |
X-RAY |
2015-02-18 | ASP | D:48 | D:173 | 135.0 | 0.9 | S | -96.6 | -123.3 | NA | NA | NA | ||||||
| 1rxr | 1 | P19793 | 92.68 | 3e-55 |
NMR |
1998-11-11 | ASP | A:44 | A:173 | 87.0 | 0.58 | S | -160.2 | 175.2 | 87.0 | 0.58 | 0.0 |
ZN |
3.455 |
HB2 |
ZN |
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| 1r0n | 3 | P19793 | 93.51 | 1e-52 |
X-RAY |
2003-10-21 | ASP | C:44 | A:139 | 113.0 | 0.753 | S | -105.0 | -97.0 | 113.0 | 0.753 | 0.0 |
ZN HOH |
4.597 5.726 |
N O |
ZN O |
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| 2han | 3 | P20153 | 80.46 | 3e-50 |
X-RAY |
2007-05-22 | GLU | C:51 | A:45 | 152.0 | 0.8 | S | -136.8 | -118.7 | 152.0 | 0.8 | 0.0 |
ZN HOH |
5.002 3.648 |
CB CB |
ZN O |
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| 1r0o | 3 | P20153 | 82.14 | 9e-50 |
X-RAY |
2003-10-21 | GLU | C:49 | A:45 | 148.0 | 0.779 | S | -112.6 | -117.1 | 144.0 | 0.758 | 0.021 |
D:P34021:0.021 |
ZN HOH |
5.005 2.798 |
CB OE2 |
ZN O |
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| 4umm | 1 | ? | 83.33 | 2e-48 |
EM |
2014-06-25 | GLU | A:42 | A:151 | 152.0 | 0.8 | S | -132.5 | -121.5 | 152.0 | 0.8 | 0.0 | ||||||
| 2nll | 3 | P19793 | 95.45 | 1e-45 |
X-RAY |
1997-03-12 | ASP | C:39 | A:173 | 106.0 | 0.707 | S | -116.7 | -111.6 | 94.0 | 0.627 | 0.08 |
D:P10828:0.08 |
ZN HOH |
4.785 3.893 |
OD2 OD2 |
ZN O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p48443-f1 | 1 | P48443 | 100.0 | 0.0 | ASP | A:177 | A:177 | 95.0 | 0.633 | S | -118.3 | -160.7 | |
| af-p28702-f1 | 1 | P28702 | 80.18 | 0.0 | ASP | A:243 | A:243 | 93.0 | 0.62 | S | -117.5 | -148.2 | |