Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 202565988 . C A CCDS1427.1:NM_001136504.1:c.1157cGg>cTg_NP_001129976.1:p.386R>L Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 86.52 1e-174 X-RAY
 2017-08-23 ARG F:249 F:388 154.0 0.684 H -55.4 -41.3 124.0 0.551 0.133 A:P63045:0.076
E:P63041:0.067
 HOH
 4.408
 O
 O
2r83 1 P21579 86.17 5e-174 X-RAY
 2008-02-12 ARG A:251 A:388 22.0 0.098 H -66.5 -40.8 22.0 0.098 0.0 CL
CL
HOH
 8.204
9.367
3.872
 NH2
O
CG
 CL
CL
O
ARG B:251 B:388 14.0 0.062 H -65.4 -41.3 14.0 0.062 0.0 CL
CL
HOH
 9.574
8.296
6.843
 O
NH2
NH1
 CL
CL
O
5ccg 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 ARG E:248 E:388 154.0 0.684 H -62.8 -47.7 154.0 0.684 0.0
ARG F:248 F:388 155.0 0.689 H -63.3 -47.7 155.0 0.689 0.0
ARG K:248 K:388 25.0 NA H -63.8 -46.8 NA NA NA
5cch 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 ARG E:248 E:388 135.0 0.6 H -62.4 -42.0 135.0 0.6 0.0
ARG F:248 F:388 151.0 0.671 H -63.2 -41.6 151.0 0.671 0.0
5cci 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 ARG E:248 E:388 133.0 0.591 H -64.1 -50.9 133.0 0.591 0.0
ARG F:248 F:388 122.0 0.542 H -63.8 -52.9 122.0 0.542 0.0
6mti 2 P21707 86.79 6e-174 EM
 2019-04-24 ARG B:248 2:669 133.0 0.591 H -64.1 -50.9 133.0 0.591 0.0
ARG C:248 3:669 130.0 0.578 H -64.1 -50.9 130.0 0.578 0.0
ARG D:248 4:669 132.0 0.587 H -64.0 -50.9 132.0 0.587 0.0
ARG E:248 5:669 132.0 0.587 H -64.0 -51.0 132.0 0.587 0.0
5kj7 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 ARG E:248 E:388 153.0 0.68 H -64.4 -47.7 153.0 0.68 0.0
ARG F:248 F:388 156.0 0.693 H -58.7 -49.2 NA NA NA
ARG K:248 K:388 25.0 NA H -65.2 -47.6 NA NA NA
5kj8 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 ARG E:248 E:388 148.0 0.658 H -62.1 -50.9 148.0 0.658 0.0
ARG F:248 F:388 148.0 0.658 H -62.8 -50.7 NA NA NA
ARG K:248 K:388 24.0 NA H -62.8 -49.5 NA NA NA
6tz3 1 P21579 84.71 1e-84 X-RAY
 2020-05-13 ARG A:124 A:389 157.0 0.698 H -60.2 -43.7 157.0 0.698 0.0 HOH
 2.123
 HH22
 O
2yoa 1 P21707 87.42 2e-84 X-RAY
 2013-03-20 ARG A:119 A:388 158.0 0.702 H -58.3 -45.6 158.0 0.702 0.0 HOH
 3.476
 CA
 O
ARG B:119 B:388 134.0 0.596 H -58.1 -44.0 NA NA NA
5t0s 1 P46096 87.42 2e-84 X-RAY
 2017-06-14 ARG A:118 A:388 154.0 0.684 H -60.1 -42.4 154.0 0.684 0.0 NA
HOH
 8.064
3.207
 N
NH1
 NA
O
2lha 1 P21579 87.42 3e-84 NMR
 2012-05-02 ARG A:119 A:388 218.0 0.969 H -68.0 -16.8 218.0 0.969 0.0
5w5d 6 P21707 87.42 3e-84 X-RAY
 2017-08-23 ARG F:119 F:388 147.0 0.653 H -65.1 -26.3 118.0 0.524 0.129 E:P63041:0.04
A:P63045:0.102
 HOH
 3.004
 NH2
 O
6u4u 1 P21579 84.71 4e-84 X-RAY
 2020-05-13 ARG A:124 A:389 154.0 0.684 H -63.1 -40.4 154.0 0.684 0.0 SO4
SO4
SO4
HOH
 4.839
7.282
1.899
2.087
 HH22
HH21
HH22
HE
 O1
O3
O1
O
1tjm 1 P21707 84.81 4e-84 X-RAY
 2004-09-28 ARG A:126 A:388 146.0 0.649 H -58.3 -45.9 146.0 0.649 0.0 GOL
HOH
 7.682
1.929
 H
HD2
 O2
H2
1tjx 1 P21707 84.81 4e-84 X-RAY
 2004-11-23 ARG A:126 A:388 151.0 0.671 H -60.7 -42.9 151.0 0.671 0.0 GOL
HOH
 7.697
1.372
 H
HH22
 O2
H1
1uov 1 P21707 84.81 4e-84 X-RAY
 2004-09-09 ARG A:126 A:388 135.0 0.6 H -56.7 -44.8 135.0 0.6 0.0 HOH
 3.099
 NE
 O
1uow 1 P21707 84.81 4e-84 X-RAY
 2004-09-16 ARG A:126 A:388 152.0 0.676 H -60.9 -43.0 152.0 0.676 0.0 GOL
HOH
 8.070
2.730
 N
NH2
 O2
O
6u4w 1 P21579 84.08 7e-84 X-RAY
 2020-05-13 ARG A:124 A:389 154.0 0.684 H -62.0 -40.3 154.0 0.684 0.0 HOH
 2.453
 HG3
 O
2n1t 5 P21579 85.81 7e-84 NMR
 2015-06-03 ARG E:126 E:388 113.0 0.502 H -60.3 -46.7 113.0 0.502 0.0
4v11 1 P21579 87.33 1e-83 X-RAY
 2015-02-25 ARG A:117 A:389 135.0 0.6 H -58.9 -47.4 135.0 0.6 0.0 HOH
 3.385
 CD
 O
5vff 1 P46096 86.75 2e-83 X-RAY
 2018-04-11 ARG A:118 A:388 155.0 0.689 H -63.5 -41.3 155.0 0.689 0.0 HOH
 2.929
 NH1
 O
5vfg 1 P46096 86.75 2e-83 X-RAY
 2018-04-11 ARG A:118 A:388 152.0 0.676 H -64.8 -42.9 152.0 0.676 0.0 HOH
 3.002
 NH1
 O
6u41 1 P21579 84.08 2e-83 X-RAY
 2020-05-13 ARG A:124 A:389 133.0 0.591 H -61.8 -42.2 133.0 0.591 0.0 HOH
 2.114
 HH11
 O
5ccj 1 P21707 84.11 8e-80 X-RAY
 2015-08-12 ARG A:119 A:388 161.0 0.716 H -70.0 -36.2 161.0 0.716 0.0 GOL
GOL
HOH
 6.935
7.998
3.243
 N
N
NH2
 O3
O3
O
ARG B:119 B:388 152.0 0.676 H -63.7 -35.2 NA NA NA
ARG C:119 C:388 161.0 0.716 H -69.2 -37.1 NA NA NA
ARG D:119 D:388 154.0 0.684 H -71.7 -27.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8n9i0-f1 1 Q8N9I0 100.0 0.0 ARG A:386 A:386 170.0 0.756 H -56.2 -46.8