Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202568476 | . | G | A | CCDS1427.1:NM_001136504.1:c.923cCg>cTg_NP_001129976.1:p.308P>L | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | PRO | F:171 | F:310 | 0.0 | 0.0 | E | -79.1 | 149.9 | 0.0 | 0.0 | 0.0 |
GOL HOH |
6.517 6.531 |
CD CD |
O2 O |
||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | PRO | A:173 | A:310 | 1.0 | 0.007 | E | -66.8 | 139.6 | 1.0 | 0.007 | 0.0 |
HOH |
6.652 |
N |
O |
||
| PRO | B:173 | B:310 | 1.0 | 0.007 | E | -65.4 | 138.6 | 1.0 | 0.007 | 0.0 |
HOH |
7.196 |
N |
O |
|||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | PRO | E:170 | E:310 | 0.0 | 0.0 | E | -79.2 | 142.9 | 0.0 | 0.0 | 0.0 |
CA CA |
7.159 9.330 |
N N |
CA CA |
||
| PRO | F:170 | F:310 | 0.0 | 0.0 | E | -78.5 | 142.3 | 0.0 | 0.0 | 0.0 |
CA |
7.655 |
N |
CA |
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| PRO | K:170 | K:310 | 0.0 | 0.0 | E | -79.6 | 141.5 | NA | NA | NA | |||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | PRO | E:170 | E:310 | 2.0 | 0.014 | E | -64.8 | 133.0 | 2.0 | 0.014 | 0.0 |
CA CA |
7.252 9.585 |
N N |
CA CA |
||
| PRO | F:170 | F:310 | 2.0 | 0.014 | E | -81.8 | 141.0 | 2.0 | 0.014 | 0.0 |
CA CA |
5.817 6.699 |
N N |
CA CA |
|||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | PRO | E:170 | E:310 | 0.0 | 0.0 | E | -81.4 | 148.6 | 0.0 | 0.0 | 0.0 |
MG |
6.528 |
N |
MG |
||
| PRO | F:170 | F:310 | 0.0 | 0.0 | E | -82.2 | 145.9 | 0.0 | 0.0 | 0.0 |
MG |
7.074 |
N |
MG |
|||||||||
| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | PRO | B:170 | 2:591 | 0.0 | 0.0 | E | -81.3 | 148.5 | 0.0 | 0.0 | 0.0 |
MG |
6.529 |
N |
MG |
||
| PRO | C:170 | 3:591 | 0.0 | 0.0 | E | -81.5 | 148.6 | 0.0 | 0.0 | 0.0 |
MG |
6.530 |
N |
MG |
|||||||||
| PRO | D:170 | 4:591 | 0.0 | 0.0 | E | -81.5 | 148.7 | 0.0 | 0.0 | 0.0 |
MG |
6.529 |
N |
MG |
|||||||||
| PRO | E:170 | 5:591 | 0.0 | 0.0 | E | -81.3 | 148.6 | 0.0 | 0.0 | 0.0 |
MG |
6.528 |
N |
MG |
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| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | PRO | E:170 | E:310 | 0.0 | 0.0 | E | -82.8 | 150.3 | 0.0 | 0.0 | 0.0 |
CA CA |
7.134 9.436 |
N N |
CA CA |
||
| PRO | F:170 | F:310 | 0.0 | 0.0 | E | -82.9 | 147.5 | NA | NA | NA | |||||||||||||
| PRO | K:170 | K:310 | 0.0 | 0.0 | E | -82.7 | 148.0 | NA | NA | NA | |||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | PRO | E:170 | E:310 | 0.0 | 0.0 | E | -73.5 | 141.8 | 0.0 | 0.0 | 0.0 |
CA CA |
5.883 8.496 |
N N |
CA CA |
||
| PRO | F:170 | F:310 | 0.0 | 0.0 | E | -75.1 | 141.8 | NA | NA | NA | |||||||||||||
| PRO | K:170 | K:310 | 0.0 | 0.0 | E | -76.0 | 140.9 | NA | NA | NA | |||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | PRO | A:46 | A:311 | 0.0 | 0.0 | E | -82.6 | 147.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.117 |
HG2 |
O |
||
| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | PRO | A:41 | A:310 | 0.0 | 0.0 | E | -76.6 | 141.9 | 0.0 | 0.0 | 0.0 |
CA CA SEP CA SCN SCN HOH |
6.603 9.055 8.477 7.395 7.715 7.186 6.902 |
N N N N C CG CD |
CA CA N CA S C O |
||
| PRO | B:41 | B:310 | 0.0 | 0.0 | E | -75.4 | 141.8 | NA | NA | NA | |||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | PRO | A:40 | A:310 | 0.0 | 0.0 | E | -77.7 | 138.6 | 0.0 | 0.0 | 0.0 |
CD HOH |
6.437 6.958 |
N CD |
CD O |
||
| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | PRO | A:41 | A:310 | 2.0 | 0.014 | E | -70.2 | 137.2 | 2.0 | 0.014 | 0.0 |
IHP |
4.134 |
O |
O21 |
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| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | PRO | F:41 | F:310 | 0.0 | 0.0 | E | -67.3 | 142.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.226 |
CD |
O |
||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | PRO | A:46 | A:311 | 0.0 | 0.0 | E | -80.5 | 147.4 | 0.0 | 0.0 | 0.0 |
SO4 SO4 HOH |
9.825 7.270 2.940 |
C HG3 HD3 |
O1 O2 O |
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| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | PRO | A:48 | A:310 | 0.0 | 0.0 | E | -79.1 | 145.1 | 0.0 | 0.0 | 0.0 |
SR HOH |
6.302 2.852 |
N HA |
SR H2 |
||
| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | PRO | A:48 | A:310 | 0.0 | 0.0 | E | -77.4 | 143.9 | 0.0 | 0.0 | 0.0 |
CA CA HOH |
8.921 6.515 1.888 |
HA N HA |
CA CA H1 |
||
| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | PRO | A:48 | A:310 | 0.0 | 0.0 | E | -76.7 | 143.1 | 0.0 | 0.0 | 0.0 |
CA CA CA HOH |
9.052 6.533 7.424 6.750 |
N N N CD |
CA CA CA O |
||
| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | PRO | A:48 | A:310 | 0.0 | 0.0 | E | -77.8 | 144.0 | 0.0 | 0.0 | 0.0 |
CA CA HOH |
9.071 6.534 3.124 |
N N CA |
CA CA O |
||
| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | PRO | A:46 | A:311 | 0.0 | 0.0 | E | -81.8 | 148.9 | 0.0 | 0.0 | 0.0 |
SO4 SO4 HOH |
6.711 9.804 3.169 |
HG3 HA HB3 |
O4 O2 O |
||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | PRO | E:48 | E:310 | 1.0 | 0.007 | -76.5 | 141.4 | 1.0 | 0.007 | 0.0 | |||||||
| 4v11 | 1 | P21579 | 87.33 | 1e-83 |
X-RAY |
2015-02-25 | PRO | A:39 | A:311 | 0.0 | 0.0 | E | -74.0 | 135.4 | 0.0 | 0.0 | 0.0 |
CA CA HOH |
6.551 8.950 6.899 |
N N CD |
CA CA O |
||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | PRO | A:40 | A:310 | 0.0 | 0.0 | E | -76.2 | 139.5 | 0.0 | 0.0 | 0.0 |
PB HOH |
6.795 6.845 |
N CD |
PB O |
||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | PRO | A:40 | A:310 | 0.0 | 0.0 | E | -72.9 | 139.6 | 0.0 | 0.0 | 0.0 |
PB HOH |
6.812 6.788 |
N CD |
PB O |
||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | PRO | A:46 | A:311 | 0.0 | 0.0 | E | -81.8 | 144.4 | 0.0 | 0.0 | 0.0 |
SO4 SO4 HOH |
9.870 7.196 4.691 |
C HG3 HB3 |
O1 O4 O |
||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | PRO | A:41 | A:310 | 0.0 | 0.0 | E | -88.6 | 149.2 | 0.0 | 0.0 | 0.0 |
GOL GOL SO4 HOH |
7.226 8.083 9.727 6.444 |
O CG C N |
C3 O1 O1 O |
||
| PRO | B:41 | B:310 | 0.0 | 0.0 | E | -81.9 | 145.4 | NA | NA | NA | |||||||||||||
| PRO | C:41 | C:310 | 0.0 | 0.0 | E | -84.0 | 148.1 | NA | NA | NA | |||||||||||||
| PRO | D:41 | D:310 | 0.0 | 0.0 | E | -85.0 | 144.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | PRO | A:308 | A:308 | 0.0 | 0.0 | E | -65.5 | 142.4 | |