Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 202571048 . C A CCDS1427.1:NM_001136504.1:c.771tgG>tgT_NP_001129976.1:p.257W>C Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 86.52 1e-174 X-RAY
 2017-08-23 TRP F:120 F:259 168.0 0.659 E -99.7 122.5 168.0 0.659 0.0
2r83 1 P21579 86.17 5e-174 X-RAY
 2008-02-12 TRP A:122 A:259 89.0 0.349 E -108.8 145.6 89.0 0.349 0.0 CL
HOH
 4.698
4.187
 O
CD1
 CL
O
TRP B:122 B:259 91.0 0.357 E -108.1 146.1 91.0 0.357 0.0 HOH
 4.177
 CD1
 O
5ccg 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 TRP E:119 E:259 109.0 0.427 E -93.8 128.9 109.0 0.427 0.0
TRP F:119 F:259 92.0 0.361 E -93.5 128.9 92.0 0.361 0.0 HOH
 7.110
 NE1
 O
TRP K:119 K:259 102.0 0.4 E -95.0 128.4 NA NA NA
5cch 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 TRP E:119 E:259 87.0 0.341 E -93.6 130.0 87.0 0.341 0.0
TRP F:119 F:259 94.0 0.369 E -95.8 129.6 94.0 0.369 0.0
5cci 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 TRP E:119 E:259 93.0 0.365 E -98.5 129.7 93.0 0.365 0.0
TRP F:119 F:259 108.0 0.424 E -100.5 129.8 108.0 0.424 0.0
6mti 2 P21707 86.79 6e-174 EM
 2019-04-24 TRP B:119 2:259 94.0 0.369 E -98.5 129.8 94.0 0.369 0.0
TRP C:119 3:259 91.0 0.357 E -98.5 129.8 62.0 0.243 0.114 R:P60881:0.02
Q:P60881:0.094
TRP D:119 4:259 93.0 0.365 E -98.4 129.7 39.0 0.153 0.212 DA:P60881:0.098
CA:P60881:0.169
TRP E:119 5:259 93.0 0.365 E -98.5 129.8 93.0 0.365 0.0
5kj7 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 TRP E:119 E:259 106.0 0.416 E -95.9 131.9 106.0 0.416 0.0
TRP F:119 F:259 93.0 0.365 E -87.3 136.9 NA NA NA
TRP K:119 K:259 103.0 0.404 E -96.8 132.1 NA NA NA
5kj8 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 TRP E:119 E:259 108.0 0.424 E -90.8 131.8 108.0 0.424 0.0
TRP F:119 F:259 106.0 0.416 E -90.2 131.4 NA NA NA
TRP K:119 K:259 106.0 0.416 E -91.3 131.4 NA NA NA
2k8m 1 Q6AI31 85.94 9e-77 NMR
 2009-03-17 TRP A:120 A:120 158.0 0.62 E -122.9 74.6 158.0 0.62 0.0
TRP D:120 D:120 169.0 0.663 E -103.1 75.8 169.0 0.663 0.0
2ki6 1 P21579 85.94 9e-77 NMR
 2010-03-09 TRP A:120 A:120 152.0 0.596 E -93.2 83.3 152.0 0.596 0.0
TRP F:120 F:120 161.0 0.631 E -93.5 87.1 124.0 0.486 0.145 C:Q99584:0.145
6mti 1 P21707 86.51 4e-76 EM
 2019-04-24 TRP A:119 1:259 91.0 0.357 E -98.5 129.7 68.0 0.267 0.09 I:P60881:0.082
C:P21707:0.008
TRP F:119 6:259 94.0 0.369 E -98.5 129.7 50.0 0.196 0.173 V:P60881:0.09
U:P60881:0.118
4wee 1 P21707 85.83 4e-76 X-RAY
 2014-10-01 TRP A:137 A:259 102.0 0.4 E -93.1 132.3 102.0 0.4 0.0 NA
NA
NA
HOH
 3.643
9.003
8.883
2.019
 HH2
HE3
HB3
HE1
 NA
NA
NA
O
5t0r 1 P46096 85.71 2e-75 X-RAY
 2017-06-14 TRP A:120 A:259 86.0 0.337 E -99.1 142.1 86.0 0.337 0.0 HOH
 2.616
 N
 O
5vfe 1 P46096 85.71 2e-75 X-RAY
 2018-04-11 TRP A:120 A:259 102.0 0.4 E -88.1 138.3 102.0 0.4 0.0 HOH
 2.630
 O
 O
TRP B:120 B:259 84.0 0.329 E -91.7 136.5 NA NA NA
1rsy 1 P21707 86.4 2e-75 X-RAY
 1995-05-08 TRP A:145 A:259 102.0 0.4 E -103.5 126.6 102.0 0.4 0.0 HOH
 2.885
 N
 O
3f00 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 TRP A:137 A:259 89.0 0.349 E -93.8 133.1 89.0 0.349 0.0 HOH
 2.824
 O
 O
3f01 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 TRP A:137 A:259 88.0 0.345 E -95.1 134.4 88.0 0.345 0.0 HOH
 2.744
 O
 O
3f04 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 TRP A:137 A:259 103.0 0.404 E -94.9 131.3 103.0 0.404 0.0 HOH
 2.848
 NE1
 O
3f05 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 TRP A:137 A:259 95.0 0.373 E -93.9 134.3 95.0 0.373 0.0 HOH
 2.857
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8n9i0-f1 1 Q8N9I0 100.0 0.0 TRP A:257 A:257 103.0 0.404 E -98.3 136.6