Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 202571079 . G A CCDS1427.1:NM_001136504.1:c.740aCa>aTa_NP_001129976.1:p.247T>I Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 86.52 1e-174 X-RAY
 2017-08-23 THR F:110 F:249 97.0 0.693 S -93.8 0.1 97.0 0.693 0.0
2r83 1 P21579 86.17 5e-174 X-RAY
 2008-02-12 THR A:112 A:249 86.0 0.614 G -103.2 4.6 86.0 0.614 0.0 CL
 5.601
 N
 CL
THR B:112 B:249 86.0 0.614 G -104.2 5.6 86.0 0.614 0.0 HOH
 4.049
 N
 O
5ccg 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 THR E:109 E:249 108.0 0.771 G -98.9 -6.3 108.0 0.771 0.0
THR F:109 F:249 102.0 0.729 G -97.8 -5.1 98.0 0.7 0.029 F:P21707:0.029
THR K:109 K:249 103.0 0.736 G -98.2 -5.7 NA NA NA
5cch 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 THR E:109 E:249 102.0 0.729 G -106.4 -15.4 102.0 0.729 0.0
THR F:109 F:249 102.0 0.729 G -106.3 -17.8 102.0 0.729 0.0
5cci 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 THR E:109 E:249 99.0 0.707 T -90.0 -22.6 99.0 0.707 0.0
THR F:109 F:249 104.0 0.743 T -90.9 -20.1 94.0 0.671 0.072 F:P21707:0.071
6mti 2 P21707 86.79 6e-174 EM
 2019-04-24 THR B:109 2:249 97.0 0.693 T -89.9 -22.6 97.0 0.693 0.0
THR C:109 3:249 98.0 0.7 T -89.9 -22.6 98.0 0.7 0.0
THR D:109 4:249 96.0 0.686 T -89.9 -22.6 96.0 0.686 0.0
THR E:109 5:249 96.0 0.686 T -90.0 -22.6 96.0 0.686 0.0
5kj7 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 THR E:109 E:249 109.0 0.779 G -99.8 -5.0 109.0 0.779 0.0
THR F:109 F:249 105.0 0.75 G -104.7 7.2 NA NA NA
THR K:109 K:249 106.0 0.757 G -98.8 -4.4 NA NA NA
5kj8 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 THR E:109 E:249 98.0 0.7 G -113.5 -6.8 98.0 0.7 0.0
THR F:109 F:249 98.0 0.7 G -113.1 -5.4 NA NA NA
THR K:109 K:249 101.0 0.721 S -114.0 -7.6 NA NA NA
2k8m 1 Q6AI31 85.94 9e-77 NMR
 2009-03-17 THR A:110 A:110 115.0 0.821 T -80.6 -34.9 115.0 0.821 0.0
THR D:110 D:110 114.0 0.814 G -108.0 7.7 114.0 0.814 0.0
2ki6 1 P21579 85.94 9e-77 NMR
 2010-03-09 THR A:110 A:110 106.0 0.757 G -84.3 -6.7 42.0 0.3 0.457 B:P05230:0.457
THR F:110 F:110 106.0 0.757 G -84.1 -6.7 38.0 0.271 0.486 E:P05230:0.486
6mti 1 P21707 86.51 4e-76 EM
 2019-04-24 THR A:109 1:249 98.0 0.7 T -89.9 -22.6 98.0 0.7 0.0
THR F:109 6:249 99.0 0.707 T -90.0 -22.5 99.0 0.707 0.0
4wee 1 P21707 85.83 4e-76 X-RAY
 2014-10-01 THR A:127 A:249 116.0 0.829 G -125.5 22.9 116.0 0.829 0.0 HOH
 2.916
 O
 O
5t0r 1 P46096 85.71 2e-75 X-RAY
 2017-06-14 THR A:110 A:249 95.0 0.679 G -102.1 -4.3 95.0 0.679 0.0 HOH
 2.755
 OG1
 O
5vfe 1 P46096 85.71 2e-75 X-RAY
 2018-04-11 THR A:110 A:249 95.0 0.679 G -96.8 2.9 95.0 0.679 0.0 HOH
 2.759
 OG1
 O
THR B:110 B:249 93.0 0.664 G -97.7 -5.0 NA NA NA
1rsy 1 P21707 86.4 2e-75 X-RAY
 1995-05-08 THR A:135 A:249 97.0 0.693 G -108.5 -6.9 97.0 0.693 0.0 HOH
 5.454
 N
 O
3f00 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 THR A:127 A:249 115.0 0.821 G -118.4 13.6 115.0 0.821 0.0 HOH
 2.347
 OG1
 O
3f01 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 THR A:127 A:249 117.0 0.836 G -116.6 16.3 117.0 0.836 0.0 HOH
 2.133
 OG1
 O
3f04 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 THR A:127 A:249 91.0 0.65 G -106.0 -15.6 91.0 0.65 0.0 HOH
 2.492
 O
 O
3f05 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 THR A:127 A:249 116.0 0.829 G -117.3 11.1 116.0 0.829 0.0 HOH
 2.281
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8n9i0-f1 1 Q8N9I0 100.0 0.0 THR A:247 A:247 92.0 0.657 G -95.6 -2.8