Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 202571173 . C A CCDS1427.1:NM_001136504.1:c.646Gag>Tag_NP_001129976.1:p.216E>* Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 86.52 1e-174 X-RAY
 2017-08-23 GLU F:79 F:218 51.0 NA G -63.2 -27.8 51.0 NA NA
2r83 1 P21579 86.17 5e-174 X-RAY
 2008-02-12 GLU A:81 A:218 113.0 0.595 G -129.0 13.8 113.0 0.595 0.0 CL
 7.956
 O
 CL
GLU B:81 B:218 113.0 0.595 G -128.1 15.7 113.0 0.595 0.0
5ccg 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 GLU E:78 E:218 122.0 0.642 T -89.9 -6.6 88.0 0.463 0.179 D:P60881:0.179
C:P60881:0.005
GLU F:78 F:218 118.0 0.621 T -90.8 -7.6 118.0 0.621 0.0
GLU K:78 K:218 121.0 0.637 T -90.2 -6.2 NA NA NA
5cch 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 GLU E:78 E:218 110.0 0.579 G -96.2 -2.8 49.0 0.258 0.321 D:P60881:0.321
GLU F:78 F:218 49.0 NA H -97.4 -3.8 49.0 NA NA
5cci 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 GLU E:78 E:218 101.0 0.532 H -70.8 -24.5 65.0 0.342 0.19 D:P60881:0.189
GLU F:78 F:218 106.0 0.558 H -70.7 -22.8 106.0 0.558 0.0
6mti 2 P21707 86.79 6e-174 EM
 2019-04-24 GLU B:78 2:218 102.0 0.537 H -70.8 -24.5 102.0 0.537 0.0
GLU C:78 3:218 102.0 0.537 H -70.9 -24.5 102.0 0.537 0.0
GLU D:78 4:218 103.0 0.542 H -70.8 -24.6 101.0 0.532 0.01 V:P60881:0.011
GLU E:78 5:218 101.0 0.532 H -70.9 -24.5 101.0 0.532 0.0
5kj7 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 GLU E:78 E:218 120.0 0.632 G -83.9 -15.2 90.0 0.474 0.158 D:P60881:0.158
C:P60881:0.005
GLU F:78 F:218 120.0 0.632 T -96.2 -5.2 NA NA NA
GLU K:78 K:218 117.0 0.616 T -85.1 -17.8 NA NA NA
5kj8 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 GLU E:78 E:218 119.0 0.626 H -86.4 -10.6 91.0 0.479 0.147 D:P60881:0.116
C:P60881:0.032
GLU F:78 F:218 112.0 0.589 H -87.4 -10.5 NA NA NA
GLU K:78 K:218 114.0 0.6 S -86.9 -8.7 NA NA NA
2k8m 1 Q6AI31 85.94 9e-77 NMR
 2009-03-17 GLU A:79 A:79 85.0 0.447 G -104.2 14.7 85.0 0.447 0.0
GLU D:79 D:79 89.0 0.468 G -96.1 10.1 89.0 0.468 0.0
2ki6 1 P21579 85.94 9e-77 NMR
 2010-03-09 GLU A:79 A:79 89.0 0.468 H -91.7 -29.4 89.0 0.468 0.0
GLU F:79 F:79 91.0 0.479 H -91.7 -29.3 91.0 0.479 0.0
6mti 1 P21707 86.51 4e-76 EM
 2019-04-24 GLU A:78 1:218 101.0 0.532 H -70.8 -24.5 101.0 0.532 0.0
GLU F:78 6:218 103.0 0.542 H -70.9 -24.4 103.0 0.542 0.0
4wee 1 P21707 85.83 4e-76 X-RAY
 2014-10-01 GLU A:96 A:218 113.0 0.595 H -93.6 -7.6 113.0 0.595 0.0 HOH
 2.577
 OE2
 O
5t0r 1 P46096 85.71 2e-75 X-RAY
 2017-06-14 GLU A:79 A:218 101.0 0.532 H -95.0 -12.3 101.0 0.532 0.0 HOH
 2.598
 OE2
 O
5vfe 1 P46096 85.71 2e-75 X-RAY
 2018-04-11 GLU A:79 A:218 117.0 0.616 G -100.9 -0.9 117.0 0.616 0.0 HOH
 2.499
 O
 O
GLU B:79 B:218 99.0 0.521 G -90.2 -8.0 NA NA NA
1rsy 1 P21707 86.4 2e-75 X-RAY
 1995-05-08 GLU A:104 A:218 114.0 0.6 H -88.3 -16.0 114.0 0.6 0.0 HOH
 4.510
 O
 O
3f00 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 GLU A:96 A:218 116.0 0.611 H -93.8 -4.6 116.0 0.611 0.0 HOH
 2.665
 O
 O
3f01 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 GLU A:96 A:218 115.0 0.605 H -87.6 -5.8 115.0 0.605 0.0 HOH
 3.110
 O
 O
3f04 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 GLU A:96 A:218 112.0 0.589 H -96.6 -4.4 112.0 0.589 0.0 HOH
 2.548
 OE2
 O
3f05 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 GLU A:96 A:218 113.0 0.595 H -93.3 -11.9 113.0 0.595 0.0 HOH
 2.600
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8n9i0-f1 1 Q8N9I0 100.0 0.0 GLU A:216 A:216 109.0 0.574 H -85.6 -14.3