Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 202571552 . T A CCDS1427.1:NM_001136504.1:c.587cAt>cTt_NP_001129976.1:p.196H>L Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 86.52 1e-174 X-RAY
 2017-08-23 HIS F:59 F:198 32.0 NA -75.0 -179.6 32.0 NA NA HOH
 8.492
 C
 O
2r83 1 P21579 86.17 5e-174 X-RAY
 2008-02-12 HIS A:61 A:198 43.0 0.221 -98.2 139.0 33.0 0.169 0.052 B:P21579:0.051
 CL
CL
CL
HOH
 9.808
2.987
6.306
4.325
 CB
ND1
C
ND1
 CL
CL
CL
O
HIS B:61 B:198 42.0 0.215 -98.6 139.3 32.0 0.164 0.051 A:P21579:0.051
 CL
CL
HOH
 6.345
3.016
3.625
 C
ND1
CA
 CL
CL
O
5ccg 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 HIS E:58 E:198 43.0 0.221 -109.4 125.4 43.0 0.221 0.0 CA
CA
 8.276
8.353
 O
O
 CA
CA
HIS F:58 F:198 59.0 0.303 -110.4 128.0 59.0 0.303 0.0 CA
 6.875
 O
 CA
HIS K:58 K:198 53.0 0.272 -109.5 125.5 NA NA NA
5cch 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 HIS E:58 E:198 51.0 0.262 -103.8 117.8 51.0 0.262 0.0 CA
 8.133
 O
 CA
HIS F:58 F:198 57.0 0.292 -103.6 118.8 57.0 0.292 0.0 CA
CA
 9.151
7.782
 O
O
 CA
CA
5cci 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 HIS E:58 E:198 52.0 0.267 -93.7 133.6 52.0 0.267 0.0 MG
 7.847
 O
 MG
HIS F:58 F:198 63.0 0.323 -95.1 133.4 63.0 0.323 0.0 MG
 7.512
 O
 MG
6mti 2 P21707 86.79 6e-174 EM
 2019-04-24 HIS B:58 2:198 53.0 0.272 -93.7 133.6 53.0 0.272 0.0 MG
 7.847
 O
 MG
HIS C:58 3:198 52.0 0.267 -93.7 133.5 52.0 0.267 0.0 MG
 7.847
 O
 MG
HIS D:58 4:198 54.0 0.277 -93.7 133.6 54.0 0.277 0.0 MG
 7.848
 O
 MG
HIS E:58 5:198 52.0 0.267 -93.7 133.5 52.0 0.267 0.0 MG
 7.848
 O
 MG
5kj7 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 HIS E:58 E:198 42.0 0.215 -109.2 121.1 42.0 0.215 0.0 CA
CA
 9.195
8.174
 O
O
 CA
CA
HIS F:58 F:198 57.0 0.292 -116.7 137.9 NA NA NA
HIS K:58 K:198 55.0 0.282 -108.8 120.6 NA NA NA
5kj8 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 HIS E:58 E:198 33.0 0.169 -107.7 121.8 33.0 0.169 0.0 CA
CA
 8.459
6.762
 O
O
 CA
CA
HIS F:58 F:198 64.0 0.328 -109.4 123.0 NA NA NA
HIS K:58 K:198 52.0 0.267 -106.2 120.6 NA NA NA
2k8m 1 Q6AI31 85.94 9e-77 NMR
 2009-03-17 HIS A:59 A:59 22.0 0.113 -88.7 81.0 22.0 0.113 0.0
HIS D:59 D:59 25.0 0.128 -100.3 96.1 25.0 0.128 0.0
2ki6 1 P21579 85.94 9e-77 NMR
 2010-03-09 HIS A:59 A:59 24.0 0.123 -111.6 89.6 24.0 0.123 0.0
HIS F:59 F:59 24.0 0.123 -111.6 89.6 24.0 0.123 0.0
6mti 1 P21707 86.51 4e-76 EM
 2019-04-24 HIS A:58 1:198 53.0 0.272 -93.8 133.6 53.0 0.272 0.0 MG
 7.847
 O
 MG
HIS F:58 6:198 52.0 0.267 -93.8 133.6 52.0 0.267 0.0 MG
 7.846
 O
 MG
4wee 1 P21707 85.83 4e-76 X-RAY
 2014-10-01 HIS A:76 A:198 54.0 0.277 -105.0 115.6 54.0 0.277 0.0 NA
SO4
SO4
HOH
 9.509
9.207
9.316
2.022
 HD1
C
O
HE2
 NA
O3
O1
O
5t0r 1 P46096 85.71 2e-75 X-RAY
 2017-06-14 HIS A:59 A:198 53.0 0.272 -109.8 101.5 53.0 0.272 0.0 CD
HOH
 7.922
2.574
 O
ND1
 CD
O
5vfe 1 P46096 85.71 2e-75 X-RAY
 2018-04-11 HIS A:59 A:198 69.0 0.354 -110.5 103.5 69.0 0.354 0.0 PB
SO4
HOH
 8.571
7.698
2.758
 O
O
ND1
 PB
O1
O
HIS B:59 B:198 66.0 0.338 -109.9 104.5 NA NA NA
1rsy 1 P21707 86.4 2e-75 X-RAY
 1995-05-08 HIS A:84 A:198 54.0 0.277 -108.2 108.3 54.0 0.277 0.0 SO4
HOH
 8.999
2.681
 C
NE2
 O3
O
3f00 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 HIS A:76 A:198 44.0 0.226 -106.2 111.7 44.0 0.226 0.0 SO4
SO4
HOH
 9.166
9.248
2.521
 C
O
ND1
 O3
O2
O
3f01 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 HIS A:76 A:198 53.0 0.272 -101.7 111.2 53.0 0.272 0.0 SO4
SO4
HOH
 9.612
9.233
2.757
 C
O
ND1
 O3
O2
O
3f04 1 P21579 85.71 3e-75 X-RAY
 2009-09-08 HIS A:76 A:198 54.0 0.277 -105.3 117.3 54.0 0.277 0.0 SO4
SO4
HOH
 9.534
9.311
2.836
 C
O
NE2
 O3
O2
O
3f05 1 P21579 85.71 3e-75 X-RAY
 2009-10-06 HIS A:76 A:198 52.0 0.267 -106.2 112.9 52.0 0.267 0.0 SO4
MN
HOH
 9.098
7.634
2.823
 C
O
NE2
 O3
MN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8n9i0-f1 1 Q8N9I0 100.0 0.0 HIS A:196 A:196 51.0 0.262 -96.3 118.6