Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226567821 . C A CCDS1554.1:NM_001618.3:c.1345Gcc>Tcc_NP_001609.2:p.449A>S Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7scy 7 P09874 96.46 1e-62 EM
 2022-01-12 ALA K:86 K:449 52.0 0.452 T -76.5 -7.5 52.0 0.452 0.0
7scz 7 P09874 96.46 1e-62 EM
 2022-01-19 ALA K:86 K:449 38.0 0.33 T -78.3 -5.9 38.0 0.33 0.0
2le0 1 P27008 87.88 3e-50 NMR
 2011-10-19 ALA A:63 A:63 14.0 0.122 T -90.0 -6.6 14.0 0.122 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 ALA A:449 A:449 15.0 0.13 T -77.0 -3.4