Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226578205 . C A CCDS1554.1:NM_001618.3:c.523Gag>Tag_NP_001609.2:p.175E>* Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 GLU A:175 A:175 95.0 0.5 T -80.4 -16.4 95.0 0.5 0.0
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 GLU A:196 NA:NA DO NA DO DO DO NA NA NA
GLU B:196 B:175 103.0 0.542 T -62.2 -46.1 103.0 0.542 0.0 HOH
 3.272
 OE2
 O
GLU C:196 NA:NA DO NA DO DO DO NA NA NA
GLU D:196 D:175 101.0 0.532 T -62.2 -46.1 101.0 0.532 0.0
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 GLU A:73 A:175 76.0 0.4 G -65.2 -18.8 76.0 0.4 0.0
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 GLU A:72 A:175 140.0 0.737 T -61.8 -35.7 140.0 0.737 0.0
GLU B:72 B:175 85.0 0.447 T -78.8 -21.3 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 GLU A:72 A:175 141.0 0.742 T -61.3 -69.3 141.0 0.742 0.0
GLU B:72 B:175 118.0 0.621 T -40.2 -47.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 GLU A:175 A:175 99.0 0.521 T -74.4 -13.9