Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226578210 . C A CCDS1554.1:NM_001618.3:c.518cGg>cTg_NP_001609.2:p.173R>L Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 ARG A:173 A:173 140.0 0.622 -46.2 158.3 140.0 0.622 0.0
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 ARG A:194 NA:NA DO NA DO DO DO NA NA NA
ARG B:194 B:173 143.0 0.636 -48.3 148.5 143.0 0.636 0.0 HOH
 7.929
 C
 O
ARG C:194 NA:NA DO NA DO DO DO NA NA NA
ARG D:194 D:173 145.0 0.644 -48.5 148.4 145.0 0.644 0.0
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 ARG A:71 A:173 138.0 0.613 -129.7 154.9 138.0 0.613 0.0
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 ARG A:70 A:173 74.0 0.329 -94.7 104.5 74.0 0.329 0.0 HOH
 9.669
 N
 O
ARG B:70 B:173 127.0 0.564 -49.5 158.0 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 ARG A:70 A:173 99.0 0.44 -104.4 86.2 99.0 0.44 0.0
ARG B:70 B:173 125.0 0.556 -54.6 153.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 ARG A:173 A:173 95.0 0.422 -75.5 154.2