Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226578278 . C A CCDS1554.1:NM_001618.3:c.450caG>caT_NP_001609.2:p.150Q>H Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 GLN A:150 A:150 149.0 0.828 T -60.1 -24.0 149.0 0.828 0.0 DC
DT
DC
DG
DC
DC
DG
 9.762
3.902
1.752
4.638
9.126
8.294
5.420
 HB3
HB3
HE22
HE22
HE22
OE1
OE1
 H2''
H2''
O4'
H5'
H5
H42
H22
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 GLN A:171 NA:NA DO NA DO DO DO NA NA NA
GLN B:171 B:150 142.0 0.789 G -63.5 -24.0 95.0 0.528 0.261 A:P09874:0.261
 DA
DA
DG
DT
HOH
 3.830
6.664
8.463
7.650
5.510
 O
CG
OE1
OE1
CG
 O4'
O4'
O4'
O2
O
GLN C:171 NA:NA DO NA DO DO DO NA NA NA
GLN D:171 D:150 141.0 0.783 T -76.7 -1.4 95.0 0.528 0.255 C:P09874:0.256
 DT
DT
DA
DA
 7.391
4.460
6.413
7.840
 NE2
O
O
NE2
 O2
O4'
O4'
O4'
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 GLN A:48 A:150 173.0 0.961 G -59.9 -27.8 173.0 0.961 0.0
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 GLN A:47 A:150 149.0 0.828 E -46.9 -37.4 149.0 0.828 0.0 DG
DC
DG
HOH
 6.475
6.484
7.759
4.971
 OE1
OE1
OE1
N
 N2
O2
O4'
O
GLN B:47 B:150 142.0 0.789 G -57.7 -23.7 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 GLN A:47 A:150 157.0 0.872 G -43.1 -28.1 157.0 0.872 0.0 DG
DC
DG
 7.971
5.939
8.195
 C
O
OE1
 N2
O4'
C5'
GLN B:47 B:150 141.0 0.783 G -63.7 -23.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 GLN A:150 A:150 63.0 0.35 G -63.7 -22.5