Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226578319 . C A CCDS1554.1:NM_001618.3:c.409Gtg>Ttg_NP_001609.2:p.137V>L Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 VAL A:137 A:137 26.0 0.168 E -68.4 134.1 26.0 0.168 0.0 ZN
 8.765
 O
 ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 VAL A:158 NA:NA DO NA DO DO DO NA NA NA
VAL B:158 B:137 15.0 0.097 E -69.6 136.4 15.0 0.097 0.0 ZN
HOH
 8.602
2.724
 O
O
 ZN
O
VAL C:158 NA:NA DO NA DO DO DO NA NA NA
VAL D:158 D:137 15.0 0.097 E -69.5 136.3 15.0 0.097 0.0 ZN
HOH
 8.644
4.189
 O
CG2
 ZN
O
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 VAL A:35 A:137 2.0 0.013 E -65.6 139.8 2.0 0.013 0.0 ZN
 9.111
 O
 ZN
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 VAL A:34 A:137 31.0 0.2 E -53.5 134.0 31.0 0.2 0.0 ZN
HOH
 8.900
2.711
 O
O
 ZN
O
VAL B:34 B:137 30.0 0.194 E -61.6 132.1 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 VAL A:34 A:137 30.0 0.194 E -53.3 125.3 30.0 0.194 0.0 ZN
HOH
 8.804
8.967
 O
O
 ZN
O
VAL B:34 B:137 29.0 0.187 E -54.5 124.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 VAL A:137 A:137 15.0 0.097 E -63.3 131.7