Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226579916 . A C CCDS1554.1:NM_001618.3:c.386aTg>aGg_NP_001609.2:p.129M>R Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 MET A:129 A:129 125.0 0.676 59.3 13.2 125.0 0.676 0.0 DG
ZN
 7.804
4.841
 HA
H
 OP1
ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 MET A:150 NA:NA DO NA DO DO DO NA NA NA
MET B:150 B:129 130.0 0.703 S 65.2 27.2 130.0 0.703 0.0 DT
ZN
HOH
 7.694
5.269
8.135
 CE
N
C
 OP1
ZN
O
MET C:150 NA:NA DO NA DO DO DO NA NA NA
MET D:150 D:129 131.0 0.708 S 65.3 27.2 131.0 0.708 0.0 DT
ZN
HOH
 7.593
5.204
4.420
 CE
N
CE
 OP1
ZN
O
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 MET A:27 A:129 111.0 0.6 T 58.7 53.1 111.0 0.6 0.0 ZN
 4.873
 H
 ZN
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 MET A:26 A:129 126.0 0.681 59.5 30.5 126.0 0.681 0.0 DC
DG
ZN
HOH
 9.715
7.387
4.978
7.251
 CE
CE
N
CE
 O3'
OP1
ZN
O
MET B:26 B:129 120.0 0.649 65.7 10.9 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 MET A:26 A:129 125.0 0.676 59.5 20.3 125.0 0.676 0.0 DG
ZN
HOH
 7.903
4.864
7.514
 CE
N
SD
 OP1
ZN
O
MET B:26 B:129 123.0 0.665 62.4 18.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 MET A:129 A:129 136.0 0.735 62.4 9.3