Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226579946 . T A CCDS1554.1:NM_001618.3:c.356aAg>aTg_NP_001609.2:p.119K>M Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 LYS A:119 A:119 160.0 0.8 S -64.3 -18.4 160.0 0.8 0.0 DG
DT
DC
DC
DG
DC
DG
 9.207
6.431
6.967
5.326
2.446
2.849
8.621
 HB3
O
O
HD3
HB3
HB2
HB2
 H22
H4'
OP1
O3'
H3'
OP2
OP2
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 LYS A:140 NA:NA DO NA DO DO DO NA NA NA
LYS B:140 B:119 152.0 0.76 S -71.9 -10.3 152.0 0.76 0.0 DG
DT
DT
DG
DC
DA
DC
DT
HOH
 9.646
9.241
7.325
7.501
5.638
3.558
3.550
9.739
3.392
 O
O
O
O
CD
CD
N
N
NZ
 N2
O3'
C4'
OP1
O3'
OP1
OP1
OP2
O
LYS C:140 NA:NA DO NA DO DO DO NA NA NA
LYS D:140 D:119 154.0 0.77 S -72.0 -10.4 154.0 0.77 0.0 DC
DA
DT
DT
DG
DC
DA
DA
HOH
 5.427
3.577
3.897
9.919
9.266
9.152
7.133
7.549
4.075
 CD
NZ
N
N
O
O
O
O
CA
 O3'
OP2
OP1
OP2
N2
O3'
C4'
OP1
O
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 LYS A:17 A:119 172.0 0.86 S -67.7 -18.5 172.0 0.86 0.0
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 LYS A:16 A:119 158.0 0.79 S -77.9 -17.3 158.0 0.79 0.0 DG
DA
DC
DG
DG
DG
HOH
 5.524
3.241
3.837
9.971
7.259
6.926
4.058
 NZ
NZ
CD
N
O
O
CG
 O3'
OP2
OP2
OP2
O3'
OP1
O
LYS B:16 B:119 158.0 0.79 S -63.8 -18.8 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 LYS A:16 A:119 161.0 0.805 S -63.3 -16.7 161.0 0.805 0.0 DA
DG
DC
DG
DG
HOH
 5.863
3.856
3.811
6.349
5.332
2.725
 CD
CD
CB
O
O
NZ
 O3'
OP2
OP2
O3'
OP1
O
LYS B:16 B:119 149.0 0.745 S -70.4 -12.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 LYS A:119 A:119 146.0 0.73 S -69.0 -21.9