Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226579961 . G A CCDS1554.1:NM_001618.3:c.341gCa>gTa_NP_001609.2:p.114A>V Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 ALA A:114 A:114 5.0 0.043 E -140.2 158.6 5.0 0.043 0.0 DC
 9.938
 HB1
 OP2
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 ALA A:135 NA:NA DO NA DO DO DO NA NA NA
ALA B:135 B:114 5.0 0.043 E -123.6 162.7 5.0 0.043 0.0 HOH
 8.110
 CB
 O
ALA C:135 NA:NA DO NA DO DO DO NA NA NA
ALA D:135 D:114 6.0 0.052 E -123.5 162.8 6.0 0.052 0.0
2l31 1 P09874 100.0 1e-71 NMR
 2011-02-02 ALA A:12 A:114 14.0 0.122 E -133.7 157.1 14.0 0.122 0.0
3odc 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 ALA A:11 A:114 22.0 0.191 E -150.2 152.5 22.0 0.191 0.0 HOH
 4.679
 CB
 O
ALA B:11 B:114 3.0 0.026 E -138.4 153.3 NA NA NA
3ode 1 P09874 100.0 8e-65 X-RAY
 2011-01-12 ALA A:11 A:114 13.0 0.113 E -128.7 154.6 13.0 0.113 0.0 HOH
 5.790
 CB
 O
ALA B:11 B:114 5.0 0.043 E -129.7 158.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 ALA A:114 A:114 12.0 0.104 E -126.8 155.7