Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226589968 . C A CCDS1554.1:NM_001618.3:c.233cGg>cTg_NP_001609.2:p.78R>L Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 ARG A:78 A:78 144.0 0.64 -64.6 153.1 144.0 0.64 0.0
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 ARG A:99 A:78 48.0 NA -44.7 134.4 48.0 NA NA
ARG B:99 NA:NA DO NA DO DO DO NA NA NA
ARG C:99 C:78 44.0 NA -84.0 148.5 44.0 NA NA
ARG D:99 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ARG A:78 A:78 81.0 0.36 -73.7 147.2 81.0 0.36 0.0
ARG C:78 D:78 81.0 0.36 -73.8 147.1 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ARG A:78 A:78 80.0 0.356 -75.0 147.8 80.0 0.356 0.0
ARG C:78 D:78 81.0 0.36 -75.1 147.7 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ARG A:78 A:78 79.0 0.351 -73.6 146.3 79.0 0.351 0.0
ARG C:78 D:78 80.0 0.356 -73.8 146.2 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 ARG A:78 A:78 173.0 0.769 -79.1 162.9 173.0 0.769 0.0
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 ARG A:98 A:78 176.0 0.782 -60.3 144.9 176.0 0.782 0.0 HOH
 2.653
 NE
 O
ARG B:98 B:78 145.0 0.644 -57.3 147.9 145.0 0.644 0.0 HOH
 3.902
 CB
 O
ARG C:98 C:78 145.0 0.644 -52.2 147.3 NA NA NA
ARG D:98 D:78 143.0 0.636 -60.8 146.2 NA NA NA
ARG E:98 E:78 138.0 0.613 -57.3 141.6 NA NA NA
ARG F:98 F:78 144.0 0.64 -58.1 147.7 NA NA NA
ARG G:98 G:78 167.0 0.742 -54.5 147.1 NA NA NA
ARG H:98 H:78 143.0 0.636 -56.6 148.8 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 ARG A:98 A:78 154.0 0.684 -56.6 147.1 154.0 0.684 0.0 HOH
 6.848
 N
 O
ARG B:98 B:78 137.0 0.609 -59.1 153.6 137.0 0.609 0.0 HOH
 2.573
 NH2
 O
ARG C:98 C:78 153.0 0.68 -57.2 147.1 NA NA NA
ARG D:98 D:78 136.0 0.604 -60.6 152.8 NA NA NA
ARG E:98 E:78 154.0 0.684 -57.7 146.0 NA NA NA
ARG F:98 F:78 138.0 0.613 -61.2 154.9 NA NA NA
ARG G:98 G:78 154.0 0.684 -57.6 148.1 NA NA NA
ARG H:98 H:78 138.0 0.613 -58.1 155.1 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 ARG A:98 A:78 171.0 0.76 -75.7 150.8 80.0 0.356 0.404 B:P09874:0.404
ARG D:98 D:78 172.0 0.764 -76.4 150.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 ARG A:78 A:78 81.0 0.36 -63.4 149.0