Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226589978 . A C CCDS1554.1:NM_001618.3:c.223Tct>Gct_NP_001609.2:p.75S>A Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 SER A:75 A:75 76.0 0.661 G -61.5 -21.1 76.0 0.661 0.0
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 SER A:96 A:75 106.0 0.922 T -79.0 -4.9 106.0 0.922 0.0
SER B:96 NA:NA DO NA DO DO DO NA NA NA
SER C:96 C:75 109.0 0.948 G -75.2 6.9 109.0 0.948 0.0
SER D:96 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 SER A:75 A:75 31.0 0.27 T -67.4 -30.5 31.0 0.27 0.0
SER C:75 D:75 32.0 0.278 T -67.5 -30.5 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 SER A:75 A:75 33.0 0.287 T -68.3 -29.3 33.0 0.287 0.0
SER C:75 D:75 33.0 0.287 T -68.4 -29.2 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 SER A:75 A:75 31.0 0.27 T -67.8 -29.7 31.0 0.27 0.0
SER C:75 D:75 32.0 0.278 T -67.8 -29.7 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 SER A:75 A:75 97.0 0.843 G -62.9 -19.3 97.0 0.843 0.0
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 SER A:95 A:75 79.0 0.687 G -70.4 -19.6 79.0 0.687 0.0 HOH
 6.226
 N
 O
SER B:95 B:75 81.0 0.704 G -72.8 -12.2 81.0 0.704 0.0 HOH
 2.711
 O
 O
SER C:95 C:75 88.0 0.765 G -73.4 -20.4 NA NA NA
SER D:95 D:75 83.0 0.722 G -69.4 -12.5 NA NA NA
SER E:95 E:75 85.0 0.739 G -70.9 -19.9 NA NA NA
SER F:95 F:75 88.0 0.765 G -73.2 -9.2 NA NA NA
SER G:95 G:75 90.0 0.783 G -71.7 -13.6 NA NA NA
SER H:95 H:75 83.0 0.722 G -72.4 -8.6 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 SER A:95 A:75 81.0 0.704 T -63.4 -34.7 81.0 0.704 0.0 HOH
 2.631
 OG
 O
SER B:95 B:75 83.0 0.722 G -72.2 -10.0 83.0 0.722 0.0 HOH
 2.702
 OG
 O
SER C:95 C:75 79.0 0.687 T -61.5 -36.8 NA NA NA
SER D:95 D:75 84.0 0.73 G -71.7 -11.7 NA NA NA
SER E:95 E:75 79.0 0.687 T -60.8 -38.5 NA NA NA
SER F:95 F:75 83.0 0.722 G -71.8 -9.8 NA NA NA
SER G:95 G:75 78.0 0.678 T -60.6 -36.8 NA NA NA
SER H:95 H:75 84.0 0.73 G -69.5 -10.6 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 SER A:95 A:75 87.0 0.757 T -69.5 -32.7 32.0 0.278 0.479 B:P09874:0.478
SER D:95 D:75 86.0 0.748 T -69.2 -33.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 SER A:75 A:75 29.0 0.252 G -64.6 -20.0