Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226590029 . A C CCDS1554.1:NM_001618.3:c.172Tgg>Ggg_NP_001609.2:p.58W>G Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 TRP A:58 A:58 52.0 0.204 H -87.1 -17.8 52.0 0.204 0.0 ZN
 8.321
 H
 ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 TRP A:79 A:58 55.0 0.216 T -75.0 -6.0 55.0 0.216 0.0 ZN
HOH
 8.966
8.725
 N
CD1
 ZN
O
TRP B:79 NA:NA DO NA DO DO DO NA NA NA
TRP C:79 C:58 55.0 0.216 G -75.0 -6.1 55.0 0.216 0.0 ZN
 9.017
 N
 ZN
TRP D:79 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 TRP A:58 A:58 50.0 0.196 G -93.2 5.0 50.0 0.196 0.0 ZN
 8.969
 N
 ZN
TRP C:58 D:58 51.0 0.2 G -93.2 5.0 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 TRP A:58 A:58 50.0 0.196 G -93.7 3.6 50.0 0.196 0.0 ZN
 8.968
 N
 ZN
TRP C:58 D:58 52.0 0.204 G -93.7 3.7 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 TRP A:58 A:58 50.0 0.196 G -92.7 4.8 50.0 0.196 0.0 ZN
 8.962
 N
 ZN
TRP C:58 D:58 51.0 0.2 G -92.7 4.9 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 TRP A:58 A:58 16.0 0.063 H -76.0 -11.8 16.0 0.063 0.0 ZN
 8.764
 H
 ZN
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 TRP A:78 A:58 40.0 0.157 H -69.2 -37.2 40.0 0.157 0.0 ZN
HOH
 8.761
2.815
 N
O
 ZN
O
TRP B:78 B:58 50.0 0.196 H -81.6 -16.9 50.0 0.196 0.0 ZN
HOH
 8.749
3.552
 N
CZ3
 ZN
O
TRP C:78 C:58 42.0 0.165 H -72.7 -29.1 NA NA NA
TRP D:78 D:58 23.0 0.09 H -77.7 -22.9 NA NA NA
TRP E:78 E:58 42.0 0.165 H -73.7 -30.5 NA NA NA
TRP F:78 F:58 40.0 0.157 G -79.6 -14.4 NA NA NA
TRP G:78 G:58 42.0 0.165 H -72.0 -32.9 NA NA NA
TRP H:78 H:58 41.0 0.161 H -85.4 -17.1 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 TRP A:78 A:58 40.0 0.157 H -77.6 -32.1 40.0 0.157 0.0 ZN
HOH
 8.678
2.535
 N
O
 ZN
O
TRP B:78 B:58 50.0 0.196 H -85.4 -21.3 50.0 0.196 0.0 ZN
HOH
 8.616
8.352
 N
N
 ZN
O
TRP C:78 C:58 38.0 0.149 H -80.2 -30.0 NA NA NA
TRP D:78 D:58 22.0 0.086 H -84.9 -21.5 NA NA NA
TRP E:78 E:58 38.0 0.149 H -79.3 -30.1 NA NA NA
TRP F:78 F:58 42.0 0.165 H -81.7 -20.1 NA NA NA
TRP G:78 G:58 42.0 0.165 H -76.9 -29.2 NA NA NA
TRP H:78 H:58 37.0 0.145 H -86.8 -20.6 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 TRP A:78 A:58 50.0 0.196 G -92.3 4.7 50.0 0.196 0.0 ZN
 9.032
 N
 ZN
TRP D:78 D:58 49.0 0.192 G -92.7 4.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 TRP A:58 A:58 14.0 0.055 H -66.6 -23.8