Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226590039 . G A CCDS1554.1:NM_001618.3:c.162ttC>ttT_NP_001609.2:p.54F>F Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 PHE A:54 A:54 30.0 0.143 H -45.2 -52.2 30.0 0.143 0.0 ZN
 6.438
 N
 ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 PHE A:75 A:54 54.0 0.257 H -54.1 -39.1 54.0 0.257 0.0 ZN
HOH
 6.436
3.927
 N
N
 ZN
O
PHE B:75 NA:NA DO NA DO DO DO NA NA NA
PHE C:75 C:54 61.0 0.29 H -54.2 -39.1 61.0 0.29 0.0 ZN
 6.469
 N
 ZN
PHE D:75 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 PHE A:54 A:54 27.0 0.129 T -53.7 -36.5 27.0 0.129 0.0 ZN
 6.301
 N
 ZN
PHE C:54 D:54 29.0 0.138 T -53.7 -36.4 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 PHE A:54 A:54 29.0 0.138 T -54.8 -36.3 29.0 0.138 0.0 ZN
 6.302
 N
 ZN
PHE C:54 D:54 30.0 0.143 T -54.6 -36.3 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 PHE A:54 A:54 28.0 0.133 T -54.5 -36.1 28.0 0.133 0.0 ZN
 6.286
 N
 ZN
PHE C:54 D:54 29.0 0.138 T -54.4 -36.0 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 PHE A:54 A:54 30.0 0.143 H -55.4 -41.0 30.0 0.143 0.0 ZN
 6.572
 N
 ZN
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 PHE A:74 A:54 30.0 0.143 H -46.8 -49.7 30.0 0.143 0.0 ZN
HOH
 6.418
3.093
 N
N
 ZN
O
PHE B:74 B:54 27.0 0.129 H -49.9 -51.5 27.0 0.129 0.0 ZN
HOH
 6.477
2.967
 N
N
 ZN
O
PHE C:74 C:54 37.0 0.176 H -52.1 -51.7 NA NA NA
PHE D:74 D:54 27.0 0.129 H -49.1 -51.8 NA NA NA
PHE E:74 E:54 34.0 0.162 H -58.0 -52.3 NA NA NA
PHE F:74 F:54 22.0 0.105 H -46.5 -54.3 NA NA NA
PHE G:74 G:54 30.0 0.143 H -53.7 -50.7 NA NA NA
PHE H:74 H:54 24.0 0.114 H -48.0 -51.1 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 PHE A:74 A:54 23.0 0.11 H -47.2 -51.3 23.0 0.11 0.0 ZN
HOH
 6.397
2.998
 N
N
 ZN
O
PHE B:74 B:54 27.0 0.129 H -46.5 -49.9 27.0 0.129 0.0 ZN
HOH
 6.426
2.941
 N
N
 ZN
O
PHE C:74 C:54 23.0 0.11 H -49.5 -52.5 NA NA NA
PHE D:74 D:54 27.0 0.129 H -44.7 -52.0 NA NA NA
PHE E:74 E:54 25.0 0.119 H -50.9 -52.9 NA NA NA
PHE F:74 F:54 26.0 0.124 H -47.4 -52.4 NA NA NA
PHE G:74 G:54 24.0 0.114 H -50.5 -50.8 NA NA NA
PHE H:74 H:54 26.0 0.124 H -48.2 -48.8 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 PHE A:74 A:54 27.0 0.129 T -52.0 -35.3 27.0 0.129 0.0 ZN
 6.419
 N
 ZN
PHE D:74 D:54 27.0 0.129 T -51.3 -35.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 PHE A:54 A:54 20.0 0.095 H -47.3 -50.1