Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226595542 . T A CCDS1554.1:NM_001618.3:c.89aAg>aTg_NP_001609.2:p.30K>M Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 LYS A:30 A:30 124.0 0.62 T -54.4 143.5 124.0 0.62 0.0 DG
DC
DT
DC
DA
DG
 9.541
7.517
7.012
7.281
5.053
5.989
 HZ3
HZ3
HZ1
HZ3
HZ3
HA
 H21
H4'
H5''
O3'
H5''
OP1
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 LYS A:51 A:30 133.0 0.665 T -70.5 -0.1 133.0 0.665 0.0 DG
DT
DG
DT
DA
DA
HOH
 6.864
5.397
8.133
9.264
8.908
9.145
5.019
 NZ
NZ
NZ
NZ
CB
NZ
CE
 C2'
OP2
N7
O4
OP2
N6
O
LYS B:51 NA:NA DO NA DO DO DO NA NA NA
LYS C:51 C:30 133.0 0.665 T -70.3 -0.2 133.0 0.665 0.0 DT
DG
DA
DT
DG
DC
HOH
 9.091
9.210
7.253
6.477
8.749
9.922
7.321
 CD
NZ
NZ
NZ
NZ
NZ
CB
 C7
O6
C2'
O5'
N7
N4
O
LYS D:51 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 LYS A:30 A:30 111.0 0.555 T -67.3 148.7 111.0 0.555 0.0 DC
DC
DG
DA
DG
DG
 6.105
5.233
9.632
8.188
7.237
7.450
 NZ
NZ
NZ
NZ
NZ
CA
 O3'
OP1
OP1
O3'
C5'
OP1
LYS C:30 D:30 113.0 0.565 T -67.2 148.7 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 LYS A:30 A:30 110.0 0.55 T -68.1 149.0 110.0 0.55 0.0 DC
DC
DG
DA
DG
DG
 6.143
5.240
9.681
8.392
7.351
7.541
 NZ
NZ
NZ
NZ
NZ
CA
 O3'
OP1
OP2
O3'
C5'
OP1
LYS C:30 D:30 114.0 0.57 T -68.2 149.0 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 LYS A:30 A:30 111.0 0.555 T -67.2 148.8 111.0 0.555 0.0 DC
DC
DG
DA
DG
DG
 6.310
5.406
9.701
8.302
7.334
7.507
 NZ
NZ
NZ
NZ
NZ
CA
 O3'
OP1
OP1
O3'
C5'
OP1
LYS C:30 D:30 114.0 0.57 T -67.2 148.8 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 LYS A:30 A:30 60.0 0.3 S -88.8 159.1 60.0 0.3 0.0
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 LYS A:50 A:30 117.0 0.585 T -42.8 141.0 117.0 0.585 0.0 DT
DT
DG
DG
DG
DC
DG
DG
HOH
 7.873
6.376
6.343
7.173
7.741
6.360
6.332
7.155
3.493
 CE
CE
NZ
CA
CE
CE
NZ
CA
O
 O3'
OP1
OP1
OP1
O3'
OP1
OP1
OP1
O
LYS B:50 B:30 123.0 0.615 T -49.3 137.3 123.0 0.615 0.0 DT
DT
DG
DG
DG
DC
DG
DG
HOH
 8.194
7.476
6.431
7.110
8.213
7.410
6.452
7.100
2.822
 NZ
NZ
NZ
CA
NZ
NZ
NZ
CA
N
 O3'
OP1
OP1
OP1
O3'
OP1
OP1
OP1
O
LYS C:50 C:30 124.0 0.62 T -48.4 140.1 NA NA NA
LYS D:50 D:30 119.0 0.595 T -51.5 141.0 NA NA NA
LYS E:50 E:30 124.0 0.62 T -50.6 140.6 NA NA NA
LYS F:50 F:30 132.0 0.66 T -48.4 138.8 NA NA NA
LYS G:50 G:30 125.0 0.625 T -51.3 140.4 NA NA NA
LYS H:50 H:30 121.0 0.605 T -51.7 140.9 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 LYS A:50 A:30 124.0 0.62 T -53.6 138.8 124.0 0.62 0.0 DA
DG
DG
DC
DA
HOH
 8.220
6.506
7.196
8.670
7.292
3.632
 NZ
NZ
CA
CD
CE
NZ
 O3'
OP1
OP1
OP1
OP1
O
LYS B:50 B:30 129.0 0.645 T -44.2 138.8 129.0 0.645 0.0 DC
DA
DA
DG
DG
HOH
 9.247
8.028
8.022
6.260
7.003
2.768
 NZ
NZ
NZ
NZ
CA
N
 C5'
OP1
O3'
OP1
OP1
O
LYS C:50 C:30 125.0 0.625 T -53.5 139.5 NA NA NA
LYS D:50 D:30 130.0 0.65 T -48.1 140.4 NA NA NA
LYS E:50 E:30 123.0 0.615 T -52.7 138.7 NA NA NA
LYS F:50 F:30 130.0 0.65 T -45.1 139.8 NA NA NA
LYS G:50 G:30 124.0 0.62 T -53.4 139.3 NA NA NA
LYS H:50 H:30 128.0 0.64 T -43.6 140.3 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 LYS A:50 A:30 132.0 0.66 T -58.1 153.5 112.0 0.56 0.1 B:P09874:0.1
 DC
DC
DG
DA
DG
DG
 6.295
5.438
9.632
8.037
7.114
7.142
 NZ
NZ
NZ
NZ
NZ
CA
 O3'
OP1
OP2
O3'
OP1
OP1
LYS D:50 D:30 131.0 0.655 T -58.6 152.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 LYS A:30 A:30 122.0 0.61 T -54.7 144.5