Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226595549 . T A CCDS1554.1:NM_001618.3:c.82Atc>Ttc_NP_001609.2:p.28I>F Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 ILE A:28 A:28 0.0 0.0 -96.3 116.7 0.0 0.0 0.0 DA
DG
DC
DT
ZN
 8.242
5.828
5.646
9.403
5.085
 HB
HB
HD13
HD11
HG12
 O3'
OP1
OP2
OP2
ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 ILE A:49 A:28 0.0 0.0 -124.7 124.3 0.0 0.0 0.0 DA
DA
DG
DT
ZN
HOH
 9.329
7.004
6.942
9.773
6.191
6.913
 CD1
CD1
O
O
CG1
O
 O3'
OP1
OP2
C7
ZN
O
ILE B:49 NA:NA DO NA DO DO DO NA NA NA
ILE C:49 C:28 0.0 0.0 -124.8 124.3 0.0 0.0 0.0 DT
DA
DA
DT
ZN
HOH
 9.371
7.019
7.032
9.922
6.180
7.612
 CD1
CD1
O
O
CG1
O
 O3'
OP1
OP2
C7
ZN
O
ILE D:49 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ILE A:28 A:28 1.0 0.006 -73.0 114.6 1.0 0.006 0.0 DC
DG
DG
DC
ZN
 9.859
8.251
6.021
6.631
5.845
 O
O
O
CD1
CG1
 OP1
O3'
OP1
OP2
ZN
ILE C:28 D:28 0.0 0.0 -73.1 114.6 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ILE A:28 A:28 0.0 0.0 -73.0 115.2 0.0 0.0 0.0 DC
DG
DG
DC
ZN
 9.921
8.533
6.280
6.875
5.855
 O
O
O
CD1
CG1
 OP1
O3'
OP1
OP2
ZN
ILE C:28 D:28 0.0 0.0 -73.0 115.1 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ILE A:28 A:28 1.0 0.006 -73.1 114.5 1.0 0.006 0.0 DG
DG
DC
ZN
 8.372
6.117
6.820
5.833
 O
O
CD1
CG1
 O3'
OP1
OP2
ZN
ILE C:28 D:28 0.0 0.0 -73.1 114.5 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 ILE A:28 A:28 0.0 0.0 -95.6 126.8 0.0 0.0 0.0 ZN
 5.107
 HG12
 ZN
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 ILE A:48 A:28 0.0 0.0 -108.6 114.8 0.0 0.0 0.0 DG
DG
DG
DG
DG
DC
ZN
HOH
 8.524
6.265
6.463
8.518
6.257
6.555
5.919
2.415
 O
O
CD1
O
O
CD1
CG1
O
 O3'
OP1
OP2
O3'
OP1
OP2
ZN
O
ILE B:48 B:28 0.0 0.0 -98.7 109.4 0.0 0.0 0.0 DG
DG
DG
DG
DG
DC
ZN
HOH
 8.370
6.113
6.427
8.360
6.112
6.427
6.123
2.590
 O
O
CD1
O
O
CD1
CG1
O
 O3'
OP1
OP2
O3'
OP1
OP2
ZN
O
ILE C:48 C:28 0.0 0.0 -107.1 111.1 NA NA NA
ILE D:48 D:28 0.0 0.0 -102.8 109.3 NA NA NA
ILE E:48 E:28 0.0 0.0 -104.9 114.7 NA NA NA
ILE F:48 F:28 0.0 0.0 -99.1 109.6 NA NA NA
ILE G:48 G:28 0.0 0.0 -99.8 111.9 NA NA NA
ILE H:48 H:28 0.0 0.0 -100.9 112.2 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 ILE A:48 A:28 1.0 0.006 -103.6 111.4 1.0 0.006 0.0 DG
DG
DC
ZN
HOH
 8.226
6.025
6.564
5.965
2.591
 O
O
CD1
CG1
O
 O3'
OP1
OP2
ZN
O
ILE B:48 B:28 0.0 0.0 -101.2 113.5 0.0 0.0 0.0 DG
DG
DC
ZN
HOH
 8.229
6.066
6.446
6.036
2.494
 O
O
CD1
CG1
O
 O3'
OP1
OP2
ZN
O
ILE C:48 C:28 0.0 0.0 -101.4 110.3 NA NA NA
ILE D:48 D:28 0.0 0.0 -100.1 110.5 NA NA NA
ILE E:48 E:28 0.0 0.0 -102.4 111.4 NA NA NA
ILE F:48 F:28 0.0 0.0 -101.4 111.2 NA NA NA
ILE G:48 G:28 0.0 0.0 -104.2 109.3 NA NA NA
ILE H:48 H:28 0.0 0.0 -99.4 112.4 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 ILE A:48 A:28 0.0 0.0 -73.9 107.6 0.0 0.0 0.0 DG
DG
DC
ZN
 8.347
6.113
6.673
5.739
 O
O
CD1
CG1
 O3'
OP1
OP1
ZN
ILE D:48 D:28 0.0 0.0 -73.6 109.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 ILE A:28 A:28 0.0 0.0 E -94.0 111.9