Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226595561 . A C CCDS1554.1:NM_001618.3:c.70Tgc>Ggc_NP_001609.2:p.24C>G Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 CYS A:24 A:24 45.0 0.333 T -98.6 -4.0 45.0 0.333 0.0 ZN
 2.310
 SG
 ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 CYS A:45 A:24 54.0 0.4 T -94.6 -4.2 54.0 0.4 0.0 ZN
HOH
 2.231
5.685
 SG
C
 ZN
O
CYS B:45 NA:NA DO NA DO DO DO NA NA NA
CYS C:45 C:24 50.0 0.37 T -94.6 -4.0 50.0 0.37 0.0 ZN
 2.187
 SG
 ZN
CYS D:45 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 CYS A:24 A:24 49.0 0.363 T -91.7 -20.8 49.0 0.363 0.0 ZN
 2.338
 SG
 ZN
CYS C:24 D:24 49.0 0.363 T -91.8 -20.8 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 CYS A:24 A:24 46.0 0.341 T -90.6 -20.5 46.0 0.341 0.0 ZN
 2.339
 SG
 ZN
CYS C:24 D:24 44.0 0.326 T -90.6 -20.5 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 CYS A:24 A:24 48.0 0.356 T -91.5 -21.9 48.0 0.356 0.0 ZN
 2.338
 SG
 ZN
CYS C:24 D:24 48.0 0.356 T -91.5 -21.9 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 CYS A:24 A:24 58.0 0.43 T -103.2 3.7 58.0 0.43 0.0 ZN
 2.339
 SG
 ZN
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 CYS A:44 A:24 42.0 0.311 T -102.5 -10.3 42.0 0.311 0.0 ZN
HOH
 2.309
2.788
 SG
O
 ZN
O
CYS B:44 B:24 39.0 0.289 T -91.2 -16.3 39.0 0.289 0.0 ZN
HOH
 2.186
3.040
 SG
SG
 ZN
O
CYS C:44 C:24 45.0 0.333 T -97.3 -12.4 NA NA NA
CYS D:44 D:24 43.0 0.319 T -93.9 -10.7 NA NA NA
CYS E:44 E:24 43.0 0.319 T -98.8 -6.9 NA NA NA
CYS F:44 F:24 45.0 0.333 T -96.8 -10.9 NA NA NA
CYS G:44 G:24 39.0 0.289 T -103.4 -3.3 NA NA NA
CYS H:44 H:24 41.0 0.304 T -102.0 -11.6 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 CYS A:44 A:24 44.0 0.326 T -101.9 -9.4 44.0 0.326 0.0 ZN
HOH
 2.346
3.202
 SG
CB
 ZN
O
CYS B:44 B:24 43.0 0.319 T -99.7 -12.1 43.0 0.319 0.0 ZN
HOH
 2.299
3.205
 SG
CA
 ZN
O
CYS C:44 C:24 45.0 0.333 T -100.7 -11.5 NA NA NA
CYS D:44 D:24 41.0 0.304 T -99.5 -10.2 NA NA NA
CYS E:44 E:24 45.0 0.333 T -102.2 -7.2 NA NA NA
CYS F:44 F:24 42.0 0.311 T -101.6 -9.4 NA NA NA
CYS G:44 G:24 44.0 0.326 T -102.9 -6.9 NA NA NA
CYS H:44 H:24 42.0 0.311 T -99.4 -12.4 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 CYS A:44 A:24 53.0 0.393 T -91.6 -32.3 53.0 0.393 0.0 ZN
 2.325
 SG
 ZN
CYS D:44 D:24 52.0 0.385 T -91.8 -31.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 CYS A:24 A:24 49.0 0.363 T -103.2 -4.7