Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 226595576 . C A CCDS1554.1:NM_001618.3:c.55Gcc>Tcc_NP_001609.2:p.19A>S Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2n8a 1 P09874 100.0 1e-152 NMR
 2015-12-02 ALA A:19 A:19 23.0 0.2 -66.0 141.1 23.0 0.2 0.0 DG
DG
DA
DG
DC
DT
ZN
 9.697
9.223
5.168
2.419
2.984
7.483
8.377
 N
N
HB3
HB3
HA
HA
O
 H21
H4'
O3'
H5''
OP1
OP2
ZN
4av1 1 P09874 98.02 1e-140 X-RAY
 2012-06-13 ALA A:40 A:19 17.0 0.148 -69.1 162.3 17.0 0.148 0.0 DA
DA
DG
DT
DA
ZN
HOH
 6.318
3.933
4.146
7.819
9.790
8.876
7.989
 CA
N
N
N
N
O
C
 O3'
C2'
OP2
C7
N6
ZN
O
ALA B:40 NA:NA DO NA DO DO DO NA NA NA
ALA C:40 C:19 14.0 0.122 -69.1 161.8 14.0 0.122 0.0 DA
DT
DA
DA
DT
ZN
HOH
 9.773
6.281
4.162
4.301
7.823
8.854
7.114
 N
CA
CA
N
N
O
N
 N6
O3'
O5'
OP2
C7
ZN
O
ALA D:40 NA:NA DO NA DO DO DO NA NA NA
4opx 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ALA A:19 A:19 32.0 0.278 -61.7 141.0 32.0 0.278 0.0 DA
DC
DG
DG
DC
ZN
 8.161
8.634
5.522
3.538
3.457
8.740
 N
N
CB
CB
CB
O
 C4'
OP1
O3'
OP1
OP2
ZN
ALA C:19 D:19 32.0 0.278 -61.7 141.0 NA NA NA
4oqa 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ALA A:19 A:19 32.0 0.278 -63.0 141.5 32.0 0.278 0.0 DA
DC
DG
DG
DC
ZN
 8.244
8.653
5.712
3.646
3.435
8.799
 N
N
CB
CB
CB
O
 C4'
OP1
O3'
O3'
OP2
ZN
ALA C:19 D:19 32.0 0.278 -63.0 141.5 NA NA NA
4oqb 1 P09874 100.0 5e-62 X-RAY
 2014-07-02 ALA A:19 A:19 32.0 0.278 -63.5 140.9 32.0 0.278 0.0 DA
DC
DG
DG
DC
ZN
 8.437
8.769
5.578
3.595
3.449
8.737
 N
N
CB
CB
CB
O
 C4'
OP1
O3'
C3'
OP2
ZN
ALA C:19 D:19 32.0 0.278 -63.4 140.9 NA NA NA
2l30 1 P09874 100.0 4e-71 NMR
 2011-02-02 ALA A:19 A:19 9.0 0.078 -93.2 148.2 9.0 0.078 0.0 ZN
 9.174
 O
 ZN
3od8 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 ALA A:39 A:19 20.0 0.174 -65.3 138.6 20.0 0.174 0.0 DC
DT
DG
DG
DG
DA
DG
DG
DG
DC
ZN
HOH
 9.589
9.599
6.091
3.635
3.408
9.522
9.552
6.084
3.648
3.507
8.347
2.957
 N
N
N
CA
CB
N
N
N
CA
CB
O
N
 C4'
OP1
O3'
O3'
OP2
C4'
OP1
O3'
O3'
OP2
ZN
O
ALA B:39 B:19 21.0 0.183 -60.9 137.0 21.0 0.183 0.0 DC
DG
DG
DG
DA
DG
DG
DC
ZN
HOH
 9.671
6.020
3.531
3.680
9.569
6.014
3.521
3.705
8.506
3.014
 N
N
CA
CA
N
N
CA
CA
O
N
 C4'
O3'
O3'
OP1
C4'
O3'
O3'
OP1
ZN
O
ALA C:39 C:19 19.0 0.165 -62.7 136.7 NA NA NA
ALA D:39 D:19 21.0 0.183 -63.5 136.9 NA NA NA
ALA E:39 E:19 19.0 0.165 -59.7 137.2 NA NA NA
ALA F:39 F:19 22.0 0.191 -65.8 138.1 NA NA NA
ALA G:39 G:19 20.0 0.174 -63.0 138.0 NA NA NA
ALA H:39 H:19 20.0 0.174 -61.2 139.2 NA NA NA
3oda 1 P09874 100.0 1e-62 X-RAY
 2011-01-12 ALA A:39 A:19 20.0 0.174 -69.1 140.7 20.0 0.174 0.0 DG
DG
DC
DG
ZN
HOH
 5.903
3.708
3.524
9.467
8.324
2.817
 N
CA
CB
N
O
N
 O3'
O3'
OP2
C4'
ZN
O
ALA B:39 B:19 22.0 0.191 -73.3 143.9 22.0 0.191 0.0 DG
DG
DC
ZN
HOH
 6.013
3.504
3.547
8.590
3.048
 N
CA
CB
O
N
 O3'
O3'
OP2
ZN
O
ALA C:39 C:19 21.0 0.183 -69.1 140.0 NA NA NA
ALA D:39 D:19 22.0 0.191 -69.7 143.1 NA NA NA
ALA E:39 E:19 22.0 0.191 -67.7 140.7 NA NA NA
ALA F:39 F:19 23.0 0.2 -71.6 143.0 NA NA NA
ALA G:39 G:19 20.0 0.174 -67.6 143.2 NA NA NA
ALA H:39 H:19 22.0 0.191 -71.0 143.0 NA NA NA
4dqy 1 P09874 100.0 1e-62 X-RAY
 2012-05-30 ALA A:39 A:19 36.0 0.313 S -70.5 139.4 36.0 0.313 0.0 DA
DC
DG
DG
DC
ZN
 8.132
8.768
5.522
3.237
3.251
8.670
 N
N
CB
CB
CA
O
 C4'
OP1
O3'
O3'
OP1
ZN
ALA D:39 D:19 34.0 0.296 S -69.7 139.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09874-f1 1 P09874 100.0 0.0 ALA A:19 A:19 19.0 0.165 E -87.7 131.0