Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 228284918 . T A CCDS1565.1:NM_001024226.1:c.103Tac>Aac_NP_001019397.1:p.35Y>N Homo sapiens ADP ribosylation factor 1 (ARF1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1r8q 1 P84080 100.0 9e-135 X-RAY
 2004-01-20 TYR A:35 A:35 145.0 0.63 H -61.1 -38.7 145.0 0.63 0.0 MG
G3D
HOH
 7.487
6.533
3.416
 OH
CD2
CE1
 MG
O1A
O
TYR C:35 B:35 143.0 0.622 H -61.6 -35.4 NA NA NA
1rrf 1 P84079 100.0 9e-135 X-RAY
 1996-06-20 TYR A:35 A:35 128.0 0.557 H -66.4 -43.4 128.0 0.557 0.0 MG
GDP
 9.477
8.237
 N
N
 MG
O1A
1rrg 1 P84079 100.0 9e-135 X-RAY
 1996-06-20 TYR A:35 A:35 159.0 0.691 H -64.1 -35.2 76.0 0.33 0.361 B:P84079:0.361
 MG
GDP
HOH
 9.728
7.611
3.325
 N
CB
CE1
 MG
O1A
O
TYR B:35 B:35 162.0 0.704 H -72.0 -30.3 79.0 0.343 0.361 A:P84079:0.361
 MG
GDP
HOH
 9.763
7.354
2.529
 N
CB
O
 MG
O1A
O
1hur 1 P84077 100.0 9e-134 X-RAY
 1995-07-10 TYR A:34 A:35 160.0 0.696 H -68.3 -39.1 78.0 0.339 0.357 B:P84077:0.357
 MG
GDP
HOH
 9.580
7.638
2.567
 N
CB
O
 MG
O1A
O
TYR B:34 B:35 179.0 0.778 H -65.1 -38.7 93.0 0.404 0.374 A:P84077:0.374
 MG
GDP
HOH
 9.551
7.412
3.897
 N
CB
CD1
 MG
O1A
O
3o47 1 Q8N6T3,P84077 99.42 7e-125 X-RAY
 2010-08-11 TYR A:183 A:165 141.0 0.613 H -60.5 -45.8 141.0 0.613 0.0 GDP
 7.649
 CB
 O1A
TYR B:183 B:165 55.0 NA H -61.1 -43.6 NA NA NA
7dn8 2 P84077 98.21 4e-122 X-RAY
 2021-12-15 TYR B:23 D:35 41.0 0.178 H -85.0 -11.6 0.0 0.0 0.178 A:Q8ZPY9:0.178
 MG
GDP
HOH
 7.831
7.631
2.657
 CE2
CD2
OH
 MG
O1A
O
TYR D:23 B:35 43.0 0.187 H -85.5 -11.2 NA NA NA
TYR F:23 F:35 42.0 0.183 H -85.8 -11.4 NA NA NA
TYR H:23 H:35 40.0 0.174 H -85.3 -11.7 NA NA NA
6cm9 3 P84077 96.53 6e-122 EM
 2018-08-08 TYR D:47 C:35 52.0 0.226 H -78.9 -11.5 24.0 0.104 0.122 C:Q10567:0.122
 GTP
MG
 7.519
7.208
 CD2
CE2
 O1A
MG
TYR F:47 H:35 43.0 0.187 H -100.6 2.1 33.0 0.143 0.044 E:P22892:0.043
 GTP
MG
 7.457
6.950
 CD2
CE2
 O1A
MG
6d83 3 P84077 96.53 6e-122 EM
 2018-08-08 TYR D:47 C:35 46.0 0.2 H -69.6 -20.3 14.0 0.061 0.139 C:Q10567:0.139
 GTP
MG
 7.245
6.941
 CD2
CE2
 O1A
MG
TYR F:47 H:35 62.0 0.27 H -75.9 -14.8 53.0 0.23 0.04 E:P22892:0.039
 GTP
MG
 7.119
7.136
 CD2
CE2
 O1A
MG
6d84 3 P84077 96.53 6e-122 EM
 2018-08-08 TYR D:47 C:35 41.0 0.178 H -78.9 -11.7 12.0 0.052 0.126 C:Q10567:0.126
 GTP
MG
 7.159
7.011
 CD2
CE2
 O1A
MG
TYR F:47 H:35 55.0 0.239 H -83.5 -7.9 42.0 0.183 0.056 E:P22892:0.057
 GTP
MG
 6.770
6.857
 CD2
CE2
 O1A
MG
TYR L:47 I:35 45.0 0.196 H -74.6 -11.8 14.0 0.061 0.135 K:Q10567:0.135
 GTP
MG
 6.975
6.683
 CD2
CE2
 O2A
MG
TYR N:47 N:35 56.0 0.243 H -83.6 -3.9 41.0 0.178 0.065 M:P22892:0.065
 GTP
MG
 6.518
6.550
 CD2
CE2
 O2A
MG
6dff 3 P84077 96.53 6e-122 EM
 2018-08-08 TYR D:47 C:35 52.0 0.226 H -75.2 -10.3 19.0 0.083 0.143 C:Q10567:0.143
 GTP
MG
 7.195
6.984
 CD2
CE2
 O1A
MG
TYR F:47 H:35 64.0 0.278 H -81.5 -15.6 45.0 0.196 0.082 E:P22892:0.083
 GTP
MG
 6.812
6.931
 CD2
CE2
 O1A
MG
7mge 4 P84077 100.0 1e-121 EM
 2021-06-23 TYR D:21 E:35 67.0 0.291 H -66.5 -39.4 67.0 0.291 0.0 GDP
BEF
MG
 7.112
7.816
9.267
 CE2
CE2
CE2
 O2A
F2
MG
1r8s 1 P84080 100.0 2e-121 X-RAY
 2004-01-20 TYR A:18 A:35 132.0 0.574 H -68.1 -39.1 132.0 0.574 0.0 GDP
SO3
HOH
 7.615
7.486
3.377
 N
CD1
CD2
 O1A
O1
O
1re0 1 P32889 100.0 2e-121 X-RAY
 2003-12-16 TYR A:18 A:35 156.0 0.678 H -71.8 -51.1 156.0 0.678 0.0 MG
GDP
HOH
 9.075
7.332
8.564
 N
CB
N
 MG
O1A
O
1s9d 1 P84080 100.0 2e-121 X-RAY
 2004-02-10 TYR A:18 A:35 155.0 0.674 H -65.3 -28.0 155.0 0.674 0.0 MG
GDP
HOH
 7.693
6.819
2.482
 CE2
CD2
O
 MG
O1A
O
1u81 1 P84077 100.0 2e-121 NMR
 2004-10-05 TYR A:18 A:35 157.0 0.683 H -55.9 -29.7 157.0 0.683 0.0 GDP
 6.395
 H
 O1A
4c0a 2 P84080 100.0 2e-121 X-RAY
 2013-09-25 TYR C:18 C:35 148.0 0.643 H -69.7 -33.7 NA NA NA
TYR D:18 D:35 158.0 0.687 H -69.5 -34.3 NA NA NA
TYR G:18 G:35 158.0 0.687 H -70.5 -32.7 158.0 0.687 0.0 G3D
 7.466
 N
 O2A
TYR H:18 H:35 160.0 0.696 H -70.4 -33.1 NA NA NA
6fae 2 P84077 98.8 4e-121 X-RAY
 2018-01-17 TYR B:67 B:35 53.0 NA H -66.3 -37.7 53.0 NA NA HOH
 2.392
 O
 O
6cri 3 P84077 99.39 5e-121 EM
 2018-08-01 TYR C:19 C:35 49.0 0.213 H -79.8 -5.3 20.0 0.087 0.126 B:Q10567:0.126
 GTP
MG
 7.379
7.205
 CD2
CE2
 O1A
MG
TYR E:19 H:35 42.0 0.183 H -91.2 -2.9 34.0 0.148 0.035 D:P22892:0.035
 GTP
MG
 6.956
7.018
 CD2
CE2
 O1A
MG
TYR K:19 K:35 47.0 0.204 H -80.5 -8.2 22.0 0.096 0.108 J:Q10567:0.109
 GTP
MG
 7.417
7.235
 CD2
CE2
 O1A
MG
TYR M:19 U:35 49.0 0.213 H -77.4 -11.0 36.0 0.157 0.056 L:P22892:0.057
 GTP
MG
 6.678
6.681
 CD2
CE2
 O1A
MG
TYR S:19 L:35 47.0 0.204 H -78.1 -8.2 21.0 0.091 0.113 R:Q10567:0.113
 GTP
MG
 7.375
7.161
 CD2
CE2
 O1A
MG
TYR U:19 V:35 41.0 0.178 H -92.9 2.3 33.0 0.143 0.035 T:P22892:0.035
 GTP
MG
 6.688
6.674
 CD2
CE2
 O1A
MG
7dn9 2 P84077 99.39 5e-121 X-RAY
 2021-12-15 TYR B:19 B:35 41.0 0.178 H -83.8 -12.0 2.0 0.009 0.169 A:Q8ZPY9:0.17
 MG
GDP
 9.455
7.854
 CE2
CD2
 MG
O1A
TYR D:19 D:35 41.0 0.178 H -83.1 -11.9 NA NA NA
TYR F:19 F:35 41.0 0.178 H -83.4 -12.0 NA NA NA
TYR H:19 H:35 40.0 0.174 H -82.8 -12.3 NA NA NA
4hmy 5 P84077 99.39 6e-121 X-RAY
 2013-03-06 TYR E:26 C:35 45.0 0.196 H -57.7 -24.0 33.0 0.143 0.053 B:Q10567:0.052
 GTP
MG
 7.886
8.252
 CD2
CE2
 O1A
MG
1j2j 1 Q8BSL7 99.39 4e-120 X-RAY
 2003-05-06 TYR A:20 A:35 45.0 0.196 H -83.0 -22.3 45.0 0.196 0.0 MG
GTP
HOH
 7.612
7.679
3.495
 CE2
CD2
CB
 MG
O1A
O
1o3y 1 P84078 99.39 4e-120 X-RAY
 2003-05-20 TYR A:20 A:35 44.0 0.191 H -80.0 -24.8 44.0 0.191 0.0 MG
GTP
HOH
 7.537
7.631
2.690
 CE2
CD2
OH
 MG
O1A
O
TYR B:20 B:35 40.0 0.174 H -80.3 -25.1 NA NA NA
2j59 1 P84078 99.39 4e-120 X-RAY
 2007-02-20 TYR A:20 A:35 37.0 0.161 H -83.8 -21.2 4.0 0.017 0.144 G:Q8NI19:0.143
 GTP
MG
HOH
 7.869
7.778
3.022
 CD1
CE1
OH
 O1A
MG
O
TYR B:20 B:35 34.0 0.148 H -81.7 -22.0 NA NA NA
TYR C:20 C:35 33.0 0.143 H -80.2 -24.6 NA NA NA
TYR D:20 D:35 32.0 0.139 H -84.8 -19.4 NA NA NA
TYR E:20 E:35 35.0 0.152 H -81.4 -23.8 NA NA NA
TYR F:20 F:35 31.0 0.135 H -85.4 -19.9 NA NA NA
6ii6 2 P61204 98.18 1e-119 X-RAY
 2019-08-07 TYR C:23 C:35 39.0 0.17 H -84.2 -26.7 30.0 0.13 0.04 A:None:0.039
 GTP
MG
HOH
 7.623
7.533
3.729
 CD2
CE2
CB
 O2A
MG
O
TYR D:23 D:35 43.0 0.187 H -85.3 -19.8 NA NA NA
3aq4 1 P36397 88.33 1e-116 X-RAY
 2011-01-26 TYR A:38 A:35 178.0 0.774 H -67.5 -41.0 178.0 0.774 0.0 MG
GDP
HOH
 9.252
7.662
2.711
 N
CB
O
 MG
O1A
O
TYR B:38 B:35 179.0 0.778 H -71.7 -34.1 NA NA NA
5uf8 1 Q5AND9 85.08 1e-114 X-RAY
 2017-01-25 TYR A:35 A:35 179.0 0.778 H -71.1 -30.3 179.0 0.778 0.0 GDP
HOH
 7.612
2.941
 N
O
 O2A
O
TYR B:35 B:35 182.0 0.791 H -69.6 -33.1 NA NA NA
TYR C:35 C:35 181.0 0.787 H -67.7 -35.5 NA NA NA
TYR D:35 D:35 175.0 0.761 H -68.3 -29.2 NA NA NA
6pta 1 P22274 84.18 4e-112 X-RAY
 2019-07-24 TYR A:35 A:35 173.0 0.752 H -64.0 -31.3 87.0 0.378 0.374 C:P22274:0.374
 GDP
HOH
 7.456
3.316
 N
CE2
 O1A
O
TYR B:35 B:35 173.0 0.752 H -67.0 -32.5 NA NA NA
TYR C:35 C:35 171.0 0.743 H -68.9 -25.8 83.0 0.361 0.382 A:P22274:0.383
 GDP
HOH
 7.715
2.709
 N
O
 O2A
O
TYR D:35 D:35 176.0 0.765 H -68.8 -25.7 NA NA NA
1z6x 1 P18085 81.92 2e-108 X-RAY
 2005-04-12 TYR A:35 A:35 180.0 0.783 H -58.7 -30.8 180.0 0.783 0.0 MG
GDP
HOH
 9.910
8.229
2.590
 N
CB
OH
 MG
O1A
O
TYR B:35 B:35 176.0 0.765 H -69.0 -37.8 NA NA NA
2b6h 1 P84085 83.14 9e-107 X-RAY
 2005-10-11 TYR A:47 A:35 187.0 0.813 H -66.0 -37.0 187.0 0.813 0.0 CL
GDP
HOH
 8.174
7.657
2.755
 O
CB
O
 CL
O2A
O
4ylg 1 C4LXL1 80.12 6e-102 X-RAY
 2015-05-20 TYR A:31 A:31 181.0 0.787 H -70.5 -38.4 91.0 0.396 0.391 B:C4LXL1:0.391
 GDP
MG
HOH
 7.667
9.364
2.598
 CB
N
O
 O1A
MG
O
TYR B:31 B:31 185.0 0.804 H -68.9 -32.5 97.0 0.422 0.382 A:C4LXL1:0.383
 GDP
MG
HOH
 7.693
9.428
2.794
 CB
N
O
 O1A
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84077-f1 1 P84077 100.0 4e-135 TYR A:35 A:35 66.0 0.287 H -66.6 -38.7
af-p61204-f1 1 P61204 96.13 2e-130 TYR A:35 A:35 54.0 0.235 H -69.0 -35.9
af-p18085-f1 1 P18085 81.92 1e-108 TYR A:35 A:35 55.0 0.239 H -70.2 -34.3
af-p84085-f1 1 P84085 81.92 1e-108 TYR A:35 A:35 55.0 0.239 H -69.4 -34.2