Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 228284958 . C A CCDS1565.1:NM_001024226.1:c.143aCc>aAc_NP_001019397.1:p.48T>N Homo sapiens ADP ribosylation factor 1 (ARF1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1r8q 1 P84080 100.0 9e-135 X-RAY
 2004-01-20 THR A:48 A:48 121.0 0.864 -136.5 136.8 25.0 0.179 0.685 B:Q99418:0.686
 AFB
HOH
 8.946
2.792
 CG2
OG1
 C13
O
THR C:48 B:48 136.0 0.971 -136.4 132.8 NA NA NA
1rrf 1 P84079 100.0 9e-135 X-RAY
 1996-06-20 THR A:48 A:48 43.0 0.307 E -155.5 146.1 43.0 0.307 0.0
1rrg 1 P84079 100.0 9e-135 X-RAY
 1996-06-20 THR A:48 A:48 46.0 0.329 E -144.8 148.9 46.0 0.329 0.0 GDP
HOH
 6.319
4.614
 O
N
 O2'
O
THR B:48 B:48 57.0 0.407 E -137.4 156.2 57.0 0.407 0.0 GDP
HOH
 6.113
2.995
 O
CG2
 O2'
O
1hur 1 P84077 100.0 9e-134 X-RAY
 1995-07-10 THR A:47 A:48 48.0 0.343 S -134.9 164.5 48.0 0.343 0.0 GDP
HOH
 6.698
5.275
 O
O
 O2'
O
THR B:47 B:48 71.0 0.507 E -153.0 166.6 71.0 0.507 0.0 GDP
HOH
 6.362
3.149
 O
OG1
 O2'
O
3o47 1 Q8N6T3,P84077 99.42 7e-125 X-RAY
 2010-08-11 THR A:196 A:178 63.0 0.45 E -157.1 154.0 63.0 0.45 0.0
THR B:196 B:178 60.0 0.429 E -157.4 149.9 NA NA NA
7dn8 2 P84077 98.21 4e-122 X-RAY
 2021-12-15 THR B:36 D:48 35.0 0.25 -87.3 85.8 35.0 0.25 0.0 MG
GDP
HOH
 2.332
4.385
2.464
 OG1
OG1
OG1
 MG
O2B
O
THR D:36 B:48 36.0 0.257 -87.2 86.0 NA NA NA
THR F:36 F:48 41.0 0.293 -86.8 85.4 NA NA NA
THR H:36 H:48 39.0 0.279 -87.5 86.0 NA NA NA
6cm9 3 P84077 96.53 6e-122 EM
 2018-08-08 THR D:60 C:48 15.0 0.107 -72.5 93.5 8.0 0.057 0.05 C:Q10567:0.05
 GTP
MG
 2.574
2.291
 OG1
CG2
 O1G
MG
THR F:60 H:48 19.0 0.136 -72.2 113.9 11.0 0.079 0.057 E:P22892:0.057
 GTP
MG
 2.585
2.650
 OG1
OG1
 O2G
MG
6d83 3 P84077 96.53 6e-122 EM
 2018-08-08 THR D:60 C:48 12.0 0.086 -80.2 114.1 6.0 0.043 0.043 C:Q10567:0.043
 GTP
MG
 2.271
2.238
 OG1
CG2
 O1G
MG
THR F:60 H:48 27.0 0.193 -79.5 104.0 17.0 0.121 0.072 E:P22892:0.071
 GTP
MG
 2.410
2.639
 OG1
OG1
 O1G
MG
6d84 3 P84077 96.53 6e-122 EM
 2018-08-08 THR D:60 C:48 13.0 0.093 -79.5 116.4 6.0 0.043 0.05 C:Q10567:0.05
 GTP
MG
 2.297
2.367
 OG1
CG2
 O1G
MG
THR F:60 H:48 20.0 0.143 -83.7 107.4 12.0 0.086 0.057 E:P22892:0.057
 GTP
MG
 2.466
2.635
 OG1
OG1
 O1G
MG
THR L:60 I:48 12.0 0.086 -77.7 118.2 7.0 0.05 0.036 K:Q10567:0.036
 GTP
MG
 2.260
2.109
 OG1
CG2
 O3G
MG
THR N:60 N:48 19.0 0.136 -76.6 95.2 13.0 0.093 0.043 M:P22892:0.043
 GTP
MG
 2.310
2.627
 OG1
OG1
 O3G
MG
6dff 3 P84077 96.53 6e-122 EM
 2018-08-08 THR D:60 C:48 10.0 0.071 -70.2 98.3 5.0 0.036 0.035 C:Q10567:0.036
 GTP
MG
 2.394
2.067
 OG1
CG2
 O3G
MG
THR F:60 H:48 19.0 0.136 -74.6 121.2 9.0 0.064 0.072 E:P22892:0.071
 GTP
MG
 2.582
2.644
 OG1
OG1
 O2G
MG
7mge 4 P84077 100.0 1e-121 EM
 2021-06-23 THR D:34 E:48 24.0 0.171 -64.9 138.5 24.0 0.171 0.0 GDP
BEF
MG
 5.593
2.295
4.850
 OG1
OG1
N
 O1B
F1
MG
1r8s 1 P84080 100.0 2e-121 X-RAY
 2004-01-20 THR A:31 A:48 125.0 0.893 -130.9 148.5 33.0 0.236 0.657 B:Q99418:0.657
 SO3
HOH
 8.299
2.488
 O
OG1
 O2
O
1re0 1 P32889 100.0 2e-121 X-RAY
 2003-12-16 THR A:31 A:48 132.0 0.943 -70.3 134.2 19.0 0.136 0.807 B:P47102:0.807
 AFB
HOH
 8.753
2.466
 CG2
OG1
 C13
O
1s9d 1 P84080 100.0 2e-121 X-RAY
 2004-02-10 THR A:31 A:48 115.0 0.821 -136.9 128.8 25.0 0.179 0.642 B:Q99418:0.643
 AFB
HOH
 8.949
2.538
 CG2
OG1
 C13
O
1u81 1 P84077 100.0 2e-121 NMR
 2004-10-05 THR A:31 A:48 39.0 0.279 B -102.8 136.6 39.0 0.279 0.0
4c0a 2 P84080 100.0 2e-121 X-RAY
 2013-09-25 THR C:31 C:48 138.0 0.986 67.6 106.5 NA NA NA
THR D:31 D:48 128.0 0.914 -108.2 35.1 NA NA NA
THR G:31 G:48 134.0 0.957 -48.0 143.1 19.0 0.136 0.821 B:Q6DN90:0.821
THR H:31 H:48 116.0 0.829 -147.8 -130.0 NA NA NA
6fae 2 P84077 98.8 4e-121 X-RAY
 2018-01-17 THR B:80 B:48 127.0 0.907 -57.5 142.2 16.0 0.114 0.793 A:Q5JU85:0.793
 HOH
 2.737
 OG1
 O
6cri 3 P84077 99.39 5e-121 EM
 2018-08-01 THR C:32 C:48 13.0 0.093 -73.0 103.2 7.0 0.05 0.043 B:Q10567:0.043
 GTP
MG
 2.290
2.717
 OG1
OG1
 O3G
MG
THR E:32 H:48 18.0 0.129 -75.5 115.3 9.0 0.064 0.065 D:P22892:0.064
 GTP
MG
 2.442
2.496
 OG1
OG1
 O1G
MG
THR K:32 K:48 10.0 0.071 -71.7 106.0 5.0 0.036 0.035 J:Q10567:0.036
 GTP
MG
 2.259
2.745
 OG1
OG1
 O3G
MG
THR M:32 U:48 17.0 0.121 -79.3 115.1 9.0 0.064 0.057 L:P22892:0.057
 GTP
MG
 2.444
2.480
 OG1
OG1
 O1G
MG
THR S:32 L:48 12.0 0.086 -70.9 99.9 7.0 0.05 0.036 R:Q10567:0.036
 GTP
MG
 2.329
2.757
 OG1
OG1
 O3G
MG
THR U:32 V:48 16.0 0.114 -83.5 110.2 8.0 0.057 0.057 T:P22892:0.057
 GTP
MG
 2.466
2.511
 OG1
OG1
 O1G
MG
7dn9 2 P84077 99.39 5e-121 X-RAY
 2021-12-15 THR B:32 B:48 35.0 0.25 -74.1 89.8 35.0 0.25 0.0 MG
GDP
 2.860
4.628
 OG1
OG1
 MG
O3B
THR D:32 D:48 34.0 0.243 -74.1 89.9 NA NA NA
THR F:32 F:48 36.0 0.257 -74.0 89.6 NA NA NA
THR H:32 H:48 36.0 0.257 -74.1 89.9 NA NA NA
4hmy 5 P84077 99.39 6e-121 X-RAY
 2013-03-06 THR E:39 C:48 15.0 0.107 -53.0 153.4 4.0 0.029 0.078 B:Q10567:0.079
 GTP
MG
 3.276
2.729
 OG1
OG1
 O3G
MG
1j2j 1 Q8BSL7 99.39 4e-120 X-RAY
 2003-05-06 THR A:33 A:48 23.0 0.164 -79.7 114.5 22.0 0.157 0.007 B:Q9UJY5:0.007
 MG
GTP
HOH
 2.097
2.786
2.652
 OG1
N
OG1
 MG
O2G
O
1o3y 1 P84078 99.39 4e-120 X-RAY
 2003-05-20 THR A:33 A:48 23.0 0.164 -79.6 118.5 23.0 0.164 0.0 MG
GTP
HOH
 2.069
2.736
2.658
 OG1
N
OG1
 MG
O2G
O
THR B:33 B:48 21.0 0.15 -84.8 111.5 NA NA NA
2j59 1 P84078 99.39 4e-120 X-RAY
 2007-02-20 THR A:33 A:48 25.0 0.179 -80.3 110.8 12.0 0.086 0.093 G:Q8NI19:0.093
 GTP
MG
HOH
 2.721
2.124
2.600
 N
OG1
OG1
 O3G
MG
O
THR B:33 B:48 25.0 0.179 -77.7 108.3 NA NA NA
THR C:33 C:48 25.0 0.179 -78.0 109.4 NA NA NA
THR D:33 D:48 27.0 0.193 -81.8 108.7 NA NA NA
THR E:33 E:48 25.0 0.179 -76.3 112.0 NA NA NA
THR F:33 F:48 27.0 0.193 -81.3 108.3 NA NA NA
6ii6 2 P61204 98.18 1e-119 X-RAY
 2019-08-07 THR C:36 C:48 26.0 0.186 -81.5 108.2 26.0 0.186 0.0 GTP
MG
HOH
 2.747
2.204
2.543
 N
OG1
OG1
 O3G
MG
O
THR D:36 D:48 25.0 0.179 -86.5 109.7 NA NA NA
3aq4 1 P36397 88.33 1e-116 X-RAY
 2011-01-26 THR A:51 A:48 70.0 0.5 E -143.0 150.4 70.0 0.5 0.0 HOH
 3.479
 OG1
 O
THR B:51 B:48 89.0 0.636 E -147.6 150.1 NA NA NA
5uf8 1 Q5AND9 85.08 1e-114 X-RAY
 2017-01-25 THR A:48 A:48 47.0 0.336 E -155.9 159.8 47.0 0.336 0.0 HOH
 2.272
 OG1
 O
THR B:48 B:48 70.0 0.5 E -152.6 148.0 NA NA NA
THR C:48 C:48 48.0 0.343 E -163.2 151.9 NA NA NA
THR D:48 D:48 48.0 0.343 S -123.8 173.3 NA NA NA
6pta 1 P22274 84.18 4e-112 X-RAY
 2019-07-24 THR A:48 A:48 68.0 0.486 S -126.2 167.3 68.0 0.486 0.0 GDP
HOH
 7.226
7.445
 O
O
 O2'
O
THR B:48 B:48 67.0 0.479 S -131.1 167.5 NA NA NA
THR C:48 C:48 82.0 0.586 S -132.4 162.2 82.0 0.586 0.0 GDP
HOH
 6.902
6.485
 O
N
 O2'
O
THR D:48 D:48 81.0 0.579 E -132.3 163.7 NA NA NA
1z6x 1 P18085 81.92 2e-108 X-RAY
 2005-04-12 THR A:48 A:48 30.0 0.214 E -151.8 148.9 30.0 0.214 0.0 HOH
 3.381
 CA
 O
THR B:48 B:48 48.0 0.343 E -149.6 167.6 NA NA NA
2b6h 1 P84085 83.14 9e-107 X-RAY
 2005-10-11 THR A:60 A:48 59.0 0.421 E -143.5 153.7 59.0 0.421 0.0 HOH
 3.158
 OG1
 O
4ylg 1 C4LXL1 80.12 6e-102 X-RAY
 2015-05-20 THR A:44 A:44 69.0 0.493 E -140.6 155.9 69.0 0.493 0.0 GDP
HOH
 6.340
2.543
 O
OG1
 O2'
O
THR B:44 B:44 85.0 0.607 E -144.9 151.7 85.0 0.607 0.0 GDP
HOH
 6.451
2.786
 O
OG1
 O2'
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84077-f1 1 P84077 100.0 4e-135 THR A:48 A:48 36.0 0.257 -63.4 118.3
af-p61204-f1 1 P61204 96.13 2e-130 THR A:48 A:48 24.0 0.171 -61.0 117.7
af-p18085-f1 1 P18085 81.92 1e-108 THR A:48 A:48 25.0 0.179 -63.2 120.0
af-p84085-f1 1 P84085 81.92 1e-108 THR A:48 A:48 26.0 0.186 -63.0 120.8