Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 228285045 . T A CCDS1565.1:NM_001024226.1:c.151Ttc>Atc_NP_001019397.1:p.51F>I Homo sapiens ADP ribosylation factor 1 (ARF1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1r8q 1 P84080 100.0 9e-135 X-RAY
 2004-01-20 PHE A:51 A:51 182.0 0.867 S -72.8 145.7 30.0 0.143 0.724 B:Q99418:0.724
 AFB
HOH
 3.816
2.715
 CD2
O
 C10
O
PHE C:51 B:51 187.0 0.89 S -74.2 146.2 NA NA NA
1rrf 1 P84079 100.0 9e-135 X-RAY
 1996-06-20 PHE A:51 A:51 35.0 0.167 E -93.6 87.1 35.0 0.167 0.0
1rrg 1 P84079 100.0 9e-135 X-RAY
 1996-06-20 PHE A:51 A:51 12.0 0.057 E -128.9 93.2 12.0 0.057 0.0 GDP
HOH
 5.830
4.465
 N
N
 O3'
O
PHE B:51 B:51 12.0 0.057 E -102.9 95.4 12.0 0.057 0.0 GDP
HOH
 5.555
3.942
 N
N
 O2'
O
1hur 1 P84077 100.0 9e-134 X-RAY
 1995-07-10 PHE A:50 A:51 5.0 0.024 -123.7 87.1 5.0 0.024 0.0 GDP
HOH
 5.914
4.745
 N
N
 O2'
O
PHE B:50 B:51 23.0 0.11 E -115.5 89.9 23.0 0.11 0.0 GDP
HOH
 5.632
3.029
 N
CD1
 O2'
O
3o47 1 Q8N6T3,P84077 99.42 7e-125 X-RAY
 2010-08-11 PHE A:199 A:181 17.0 0.081 E -83.3 100.3 17.0 0.081 0.0
PHE B:199 B:181 24.0 0.114 E -86.4 110.3 NA NA NA
7dn8 2 P84077 98.21 4e-122 X-RAY
 2021-12-15 PHE B:39 D:51 102.0 0.486 E -165.5 165.3 8.0 0.038 0.448 A:Q8ZPY9:0.448
 MG
GDP
HOH
 7.521
9.212
4.884
 CA
CA
O
 MG
O2B
O
PHE D:39 B:51 103.0 0.49 E -164.8 164.3 NA NA NA
PHE F:39 F:51 103.0 0.49 E -164.8 164.7 NA NA NA
PHE H:39 H:51 97.0 0.462 E -165.0 164.8 NA NA NA
6cm9 3 P84077 96.53 6e-122 EM
 2018-08-08 PHE D:63 C:51 123.0 0.586 E -152.8 -180.0 7.0 0.033 0.553 C:Q10567:0.552
 GTP
MG
 8.376
7.355
 CA
C
 O1G
MG
PHE F:63 H:51 93.0 0.443 E -139.7 170.8 1.0 0.005 0.438 E:P22892:0.438
 GTP
MG
 8.176
7.971
 CA
C
 O2G
MG
6d83 3 P84077 96.53 6e-122 EM
 2018-08-08 PHE D:63 C:51 126.0 0.6 E -134.3 172.7 4.0 0.019 0.581 C:Q10567:0.581
 GTP
MG
 8.071
7.572
 CA
C
 O1G
MG
PHE F:63 H:51 94.0 0.448 E -143.4 178.3 2.0 0.01 0.438 E:P22892:0.438
 GTP
MG
 7.728
8.180
 CA
C
 O1G
MG
6d84 3 P84077 96.53 6e-122 EM
 2018-08-08 PHE D:63 C:51 127.0 0.605 E -133.0 -179.0 2.0 0.01 0.595 C:Q10567:0.595
 GTP
MG
 7.872
7.508
 CA
C
 O1G
MG
PHE F:63 H:51 101.0 0.481 E -146.2 177.0 0.0 0.0 0.481 E:P22892:0.481
 GTP
MG
 7.840
8.371
 CA
C
 O1G
MG
PHE L:63 I:51 129.0 0.614 E -136.0 179.9 3.0 0.014 0.6 K:Q10567:0.6
 GTP
MG
 7.884
7.388
 CA
C
 O3G
MG
PHE N:63 N:51 103.0 0.49 E -143.4 175.3 1.0 0.005 0.485 M:P22892:0.486
 GTP
MG
 7.735
8.207
 CA
C
 O3G
MG
6dff 3 P84077 96.53 6e-122 EM
 2018-08-08 PHE D:63 C:51 115.0 0.548 E -156.7 163.3 6.0 0.029 0.519 C:Q10567:0.519
 GTP
MG
 7.669
7.402
 CA
CA
 O3G
MG
PHE F:63 H:51 94.0 0.448 E -139.4 173.1 0.0 0.0 0.448 E:P22892:0.448
 GTP
MG
 8.073
8.038
 CA
C
 O2G
MG
7mge 4 P84077 100.0 1e-121 EM
 2021-06-23 PHE D:37 E:51 109.0 0.519 179.4 168.3 38.0 0.181 0.338 B:Q8TEV9:0.019
C:Q96LT7:0.333
 BEF
 6.727
 CA
 F1
1r8s 1 P84080 100.0 2e-121 X-RAY
 2004-01-20 PHE A:34 A:51 131.0 0.624 -71.9 155.2 3.0 0.014 0.61 B:Q99418:0.61
 SO3
HOH
 7.426
2.650
 C
O
 O1
O
1re0 1 P32889 100.0 2e-121 X-RAY
 2003-12-16 PHE A:34 A:51 191.0 0.91 S -75.5 151.7 29.0 0.138 0.772 B:P47102:0.771
 AFB
HOH
 3.737
2.640
 CD2
O
 C6
O
1s9d 1 P84080 100.0 2e-121 X-RAY
 2004-02-10 PHE A:34 A:51 186.0 0.886 -72.9 149.9 34.0 0.162 0.724 B:Q99418:0.724
 AFB
HOH
 3.849
2.654
 CD2
O
 C10
O
1u81 1 P84077 100.0 2e-121 NMR
 2004-10-05 PHE A:34 A:51 29.0 0.138 B -81.2 106.4 29.0 0.138 0.0 MG
 9.309
 C
 MG
4c0a 2 P84080 100.0 2e-121 X-RAY
 2013-09-25 PHE C:34 C:51 146.0 0.695 S -69.7 167.4 NA NA NA
PHE D:34 D:51 118.0 0.562 S -73.9 -178.9 NA NA NA
PHE G:34 G:51 122.0 0.581 S -74.2 172.1 5.0 0.024 0.557 B:Q6DN90:0.557
 G3D
 9.740
 CB
 O1B
PHE H:34 H:51 119.0 0.567 S -72.6 -177.1 NA NA NA
6fae 2 P84077 98.8 4e-121 X-RAY
 2018-01-17 PHE B:83 B:51 129.0 0.614 S -91.3 146.5 1.0 0.005 0.609 A:Q5JU85:0.61
 HOH
 3.619
 O
 O
6cri 3 P84077 99.39 5e-121 EM
 2018-08-01 PHE C:35 C:51 126.0 0.6 E -150.6 177.0 7.0 0.033 0.567 B:Q10567:0.567
 GTP
MG
 7.819
7.762
 CA
C
 O3G
MG
PHE E:35 H:51 94.0 0.448 E -130.1 -177.7 1.0 0.005 0.443 D:P22892:0.443
 GTP
MG
 7.460
7.516
 CA
C
 O1G
MG
PHE K:35 K:51 124.0 0.59 E -153.3 179.0 5.0 0.024 0.566 J:Q10567:0.567
 GTP
MG
 7.773
7.759
 CA
C
 O3G
MG
PHE M:35 U:51 93.0 0.443 E -137.7 -176.4 2.0 0.01 0.433 L:P22892:0.433
 GTP
MG
 7.498
7.532
 CA
C
 O1G
MG
PHE S:35 L:51 128.0 0.61 E -150.9 -178.9 6.0 0.029 0.581 R:Q10567:0.581
 GTP
MG
 7.737
7.722
 CA
C
 O3G
MG
PHE U:35 V:51 95.0 0.452 E -136.8 177.0 0.0 0.0 0.452 T:P22892:0.452
 GTP
MG
 7.529
7.600
 CA
C
 O1G
MG
7dn9 2 P84077 99.39 5e-121 X-RAY
 2021-12-15 PHE B:35 B:51 95.0 0.452 E -161.8 152.6 7.0 0.033 0.419 A:Q8ZPY9:0.419
 MG
GDP
 8.384
9.611
 CA
CA
 MG
O3B
PHE D:35 D:51 94.0 0.448 E -161.2 152.4 NA NA NA
PHE F:35 F:51 98.0 0.467 E -161.1 151.8 NA NA NA
PHE H:35 H:51 95.0 0.452 E -161.5 152.4 NA NA NA
4hmy 5 P84077 99.39 6e-121 X-RAY
 2013-03-06 PHE E:42 C:51 64.0 0.305 20.4 99.7 4.0 0.019 0.286 B:Q10567:0.286
 GTP
MG
 8.285
8.023
 N
CA
 O3G
MG
1j2j 1 Q8BSL7 99.39 4e-120 X-RAY
 2003-05-06 PHE A:36 A:51 97.0 0.462 E -153.0 169.7 7.0 0.033 0.429 B:Q9UJY5:0.429
 MG
GTP
HOH
 7.294
7.939
2.870
 C
CA
O
 MG
O2G
O
1o3y 1 P84078 99.39 4e-120 X-RAY
 2003-05-20 PHE A:36 A:51 88.0 0.419 E -154.9 160.6 88.0 0.419 0.0 MG
GTP
HOH
 7.429
8.066
2.725
 CA
CA
O
 MG
O2G
O
PHE B:36 B:51 89.0 0.424 E -145.7 160.4 NA NA NA
2j59 1 P84078 99.39 4e-120 X-RAY
 2007-02-20 PHE A:36 A:51 96.0 0.457 E -157.6 158.7 3.0 0.014 0.443 G:Q8NI19:0.443
 GTP
MG
HOH
 7.997
7.331
3.147
 CA
CA
N
 O3G
MG
O
PHE B:36 B:51 96.0 0.457 E -158.3 162.1 NA NA NA
PHE C:36 C:51 98.0 0.467 E -156.7 161.1 NA NA NA
PHE D:36 D:51 94.0 0.448 E -157.7 160.0 NA NA NA
PHE E:36 E:51 95.0 0.452 E -157.4 163.0 NA NA NA
PHE F:36 F:51 92.0 0.438 E -158.5 159.7 NA NA NA
6ii6 2 P61204 98.18 1e-119 X-RAY
 2019-08-07 PHE C:39 C:51 89.0 0.424 E -150.0 159.8 8.0 0.038 0.386 A:None:0.386
 GTP
MG
HOH
 8.157
7.580
2.771
 CA
C
O
 O3G
MG
O
PHE D:39 D:51 93.0 0.443 E -156.3 155.9 NA NA NA
3aq4 1 P36397 88.33 1e-116 X-RAY
 2011-01-26 PHE A:54 A:51 29.0 0.138 E -123.5 97.6 29.0 0.138 0.0 HOH
 3.513
 CD1
 O
PHE B:54 B:51 72.0 0.343 E -119.3 93.7 NA NA NA
5uf8 1 Q5AND9 85.08 1e-114 X-RAY
 2017-01-25 PHE A:51 A:51 6.0 0.029 E -141.3 96.4 6.0 0.029 0.0 HOH
 3.487
 N
 O
PHE B:51 B:51 6.0 0.029 E -112.9 87.2 NA NA NA
PHE C:51 C:51 5.0 0.024 E -136.1 95.7 NA NA NA
PHE D:51 D:51 2.0 0.01 -105.3 96.8 NA NA NA
6pta 1 P22274 84.18 4e-112 X-RAY
 2019-07-24 PHE A:51 A:51 19.0 0.09 -127.2 95.6 19.0 0.09 0.0 GDP
HOH
 5.324
4.083
 N
C
 O3'
O
PHE B:51 B:51 21.0 0.1 -121.9 100.0 NA NA NA
PHE C:51 C:51 11.0 0.052 -116.3 100.3 11.0 0.052 0.0 GDP
HOH
 5.839
4.883
 N
C
 O3'
O
PHE D:51 D:51 19.0 0.09 E -121.1 100.5 NA NA NA
1z6x 1 P18085 81.92 2e-108 X-RAY
 2005-04-12 PHE A:51 A:51 18.0 0.086 E -123.9 83.7 18.0 0.086 0.0 HOH
 4.938
 C
 O
PHE B:51 B:51 1.0 0.005 E -139.6 87.7 NA NA NA
2b6h 1 P84085 83.14 9e-107 X-RAY
 2005-10-11 PHE A:63 A:51 10.0 0.048 E -120.1 90.7 10.0 0.048 0.0 HOH
 3.559
 CD1
 O
4ylg 1 C4LXL1 80.12 6e-102 X-RAY
 2015-05-20 PHE A:47 A:47 26.0 0.124 E -119.9 88.7 26.0 0.124 0.0 GDP
HOH
 5.604
3.581
 N
CA
 O2'
O
PHE B:47 B:47 70.0 0.333 E -106.1 96.0 70.0 0.333 0.0 GDP
HOH
 5.685
4.534
 N
CD1
 O2'
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84077-f1 1 P84077 100.0 4e-135 PHE A:51 A:51 108.0 0.514 E -131.8 145.3
af-p61204-f1 1 P61204 96.13 2e-130 PHE A:51 A:51 115.0 0.548 E -144.3 147.2
af-p18085-f1 1 P18085 81.92 1e-108 PHE A:51 A:51 107.0 0.51 E -146.4 149.8
af-p84085-f1 1 P84085 81.92 1e-108 PHE A:51 A:51 114.0 0.543 E -144.2 144.3