Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 228285405 | . | G | A | CCDS1565.1:NM_001024226.1:c.373Gcc>Acc_NP_001019397.1:p.125A>T | Homo sapiens ADP ribosylation factor 1 (ARF1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1r8q | 1 | P84080 | 100.0 | 9e-135 |
X-RAY |
2004-01-20 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -91.5 | 92.8 | 0.0 | 0.0 | 0.0 |
G3D HOH |
6.975 6.351 |
O CB |
O6 O |
||
| ALA | C:125 | B:125 | 0.0 | 0.0 | E | -82.8 | 88.2 | NA | NA | NA | |||||||||||||
| 1rrf | 1 | P84079 | 100.0 | 9e-135 |
X-RAY |
1996-06-20 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -78.5 | 103.4 | 0.0 | 0.0 | 0.0 |
GDP |
7.085 |
O |
O6 |
||
| 1rrg | 1 | P84079 | 100.0 | 9e-135 |
X-RAY |
1996-06-20 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -95.3 | 77.5 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.012 6.222 |
O O |
O6 O |
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| ALA | B:125 | B:125 | 0.0 | 0.0 | E | -92.7 | 90.6 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.116 5.648 |
O CB |
O6 O |
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| 1hur | 1 | P84077 | 100.0 | 9e-134 |
X-RAY |
1995-07-10 | ALA | A:124 | A:125 | 0.0 | 0.0 | E | -82.2 | 101.3 | 0.0 | 0.0 | 0.0 |
GDP HOH |
6.960 6.031 |
O O |
O6 O |
||
| ALA | B:124 | B:125 | 0.0 | 0.0 | E | -92.6 | 91.4 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.395 7.046 |
O CB |
O6 O |
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| 3o47 | 1 | Q8N6T3,P84077 | 99.42 | 7e-125 |
X-RAY |
2010-08-11 | ALA | A:273 | A:255 | 0.0 | 0.0 | E | -84.1 | 84.2 | 0.0 | 0.0 | 0.0 |
GDP |
7.289 |
O |
O6 |
||
| ALA | B:273 | B:255 | 0.0 | 0.0 | E | -84.9 | 89.2 | NA | NA | NA | |||||||||||||
| 7dn8 | 2 | P84077 | 98.21 | 4e-122 |
X-RAY |
2021-12-15 | ALA | B:113 | D:125 | 0.0 | 0.0 | E | -82.3 | 86.1 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.111 6.452 |
O CB |
O6 O |
||
| ALA | D:113 | B:125 | 0.0 | 0.0 | E | -81.9 | 85.9 | NA | NA | NA | |||||||||||||
| ALA | F:113 | F:125 | 0.0 | 0.0 | E | -82.1 | 86.1 | NA | NA | NA | |||||||||||||
| ALA | H:113 | H:125 | 0.0 | 0.0 | E | -82.2 | 85.7 | NA | NA | NA | |||||||||||||
| 6cm9 | 3 | P84077 | 96.53 | 6e-122 |
EM |
2018-08-08 | ALA | D:137 | C:125 | 1.0 | 0.009 | E | -76.6 | 101.0 | 1.0 | 0.009 | 0.0 |
GTP |
8.885 |
O |
O6 |
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| ALA | F:137 | H:125 | 0.0 | 0.0 | E | -86.4 | 73.0 | 0.0 | 0.0 | 0.0 |
GTP |
7.527 |
O |
O6 |
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| 6d83 | 3 | P84077 | 96.53 | 6e-122 |
EM |
2018-08-08 | ALA | D:137 | C:125 | 0.0 | 0.0 | E | -68.9 | 103.0 | 0.0 | 0.0 | 0.0 |
GTP |
8.121 |
O |
O6 |
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| ALA | F:137 | H:125 | 0.0 | 0.0 | E | -96.2 | 87.9 | 0.0 | 0.0 | 0.0 |
GTP |
7.410 |
O |
O6 |
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| 6d84 | 3 | P84077 | 96.53 | 6e-122 |
EM |
2018-08-08 | ALA | D:137 | C:125 | 0.0 | 0.0 | E | -68.3 | 103.5 | 0.0 | 0.0 | 0.0 |
GTP |
7.842 |
O |
O6 |
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| ALA | F:137 | H:125 | 0.0 | 0.0 | E | -104.2 | 88.6 | 0.0 | 0.0 | 0.0 |
GTP |
7.202 |
O |
O6 |
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| ALA | L:137 | I:125 | 0.0 | 0.0 | E | -67.8 | 106.3 | 0.0 | 0.0 | 0.0 |
GTP |
8.173 |
O |
O6 |
|||||||||
| ALA | N:137 | N:125 | 0.0 | 0.0 | E | -94.6 | 90.7 | 0.0 | 0.0 | 0.0 |
GTP |
7.410 |
O |
O6 |
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| 6dff | 3 | P84077 | 96.53 | 6e-122 |
EM |
2018-08-08 | ALA | D:137 | C:125 | 1.0 | 0.009 | E | -73.5 | 104.1 | 1.0 | 0.009 | 0.0 |
GTP |
8.806 |
O |
O6 |
||
| ALA | F:137 | H:125 | 0.0 | 0.0 | E | -84.2 | 81.9 | 0.0 | 0.0 | 0.0 |
GTP |
7.014 |
O |
O6 |
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| 7mge | 4 | P84077 | 100.0 | 1e-121 |
EM |
2021-06-23 | ALA | D:111 | E:125 | 6.0 | 0.052 | E | -137.1 | 173.8 | 6.0 | 0.052 | 0.0 |
GDP |
8.623 |
C |
O6 |
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| 1r8s | 1 | P84080 | 100.0 | 2e-121 |
X-RAY |
2004-01-20 | ALA | A:108 | A:125 | 0.0 | 0.0 | E | -88.7 | 88.7 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.043 6.808 |
O CB |
O6 O |
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| 1re0 | 1 | P32889 | 100.0 | 2e-121 |
X-RAY |
2003-12-16 | ALA | A:108 | A:125 | 0.0 | 0.0 | E | -82.4 | 85.8 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.027 7.000 |
O CB |
O6 O |
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| 1s9d | 1 | P84080 | 100.0 | 2e-121 |
X-RAY |
2004-02-10 | ALA | A:108 | A:125 | 0.0 | 0.0 | E | -82.8 | 87.0 | 0.0 | 0.0 | 0.0 |
GDP HOH |
6.971 6.105 |
O CB |
O6 O |
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| 1u81 | 1 | P84077 | 100.0 | 2e-121 |
NMR |
2004-10-05 | ALA | A:108 | A:125 | 14.0 | 0.122 | E | -91.2 | 72.5 | 14.0 | 0.122 | 0.0 |
GDP |
8.026 |
C |
O6 |
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| 4c0a | 2 | P84080 | 100.0 | 2e-121 |
X-RAY |
2013-09-25 | ALA | C:108 | C:125 | 0.0 | 0.0 | E | -85.5 | 86.6 | NA | NA | NA | ||||||
| ALA | D:108 | D:125 | 0.0 | 0.0 | E | -84.6 | 86.3 | NA | NA | NA | |||||||||||||
| ALA | G:108 | G:125 | 0.0 | 0.0 | E | -85.3 | 86.5 | 0.0 | 0.0 | 0.0 |
G3D |
7.146 |
O |
O6 |
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| ALA | H:108 | H:125 | 0.0 | 0.0 | E | -85.1 | 86.3 | NA | NA | NA | |||||||||||||
| 6fae | 2 | P84077 | 98.8 | 4e-121 |
X-RAY |
2018-01-17 | ALA | B:157 | B:125 | 0.0 | 0.0 | E | -79.9 | 93.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.227 |
CB |
O |
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| 6cri | 3 | P84077 | 99.39 | 5e-121 |
EM |
2018-08-01 | ALA | C:109 | C:125 | 1.0 | 0.009 | E | -75.2 | 102.0 | 1.0 | 0.009 | 0.0 |
GTP |
8.010 |
O |
O6 |
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| ALA | E:109 | H:125 | 0.0 | 0.0 | E | -83.6 | 75.6 | 0.0 | 0.0 | 0.0 |
GTP |
6.965 |
O |
O6 |
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| ALA | K:109 | K:125 | 1.0 | 0.009 | E | -77.5 | 103.4 | 1.0 | 0.009 | 0.0 |
GTP |
8.014 |
O |
O6 |
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| ALA | M:109 | U:125 | 0.0 | 0.0 | E | -83.8 | 75.4 | 0.0 | 0.0 | 0.0 |
GTP |
6.998 |
O |
O6 |
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| ALA | S:109 | L:125 | 2.0 | 0.017 | E | -78.7 | 102.4 | 2.0 | 0.017 | 0.0 |
GTP |
8.021 |
O |
O6 |
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| ALA | U:109 | V:125 | 0.0 | 0.0 | E | -94.1 | 73.5 | 0.0 | 0.0 | 0.0 |
GTP |
6.941 |
O |
O6 |
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| 7dn9 | 2 | P84077 | 99.39 | 5e-121 |
X-RAY |
2021-12-15 | ALA | B:109 | B:125 | 0.0 | 0.0 | E | -75.6 | 80.5 | 0.0 | 0.0 | 0.0 |
GDP |
6.974 |
O |
O6 |
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| ALA | D:109 | D:125 | 0.0 | 0.0 | E | -75.9 | 80.2 | NA | NA | NA | |||||||||||||
| ALA | F:109 | F:125 | 0.0 | 0.0 | E | -76.1 | 80.0 | NA | NA | NA | |||||||||||||
| ALA | H:109 | H:125 | 0.0 | 0.0 | E | -76.0 | 80.5 | NA | NA | NA | |||||||||||||
| 4hmy | 5 | P84077 | 99.39 | 6e-121 |
X-RAY |
2013-03-06 | ALA | E:116 | C:125 | 2.0 | 0.017 | E | -79.9 | 77.8 | 2.0 | 0.017 | 0.0 |
GTP |
7.745 |
O |
O6 |
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| 1j2j | 1 | Q8BSL7 | 99.39 | 4e-120 |
X-RAY |
2003-05-06 | ALA | A:110 | A:125 | 0.0 | 0.0 | E | -89.6 | 88.1 | 0.0 | 0.0 | 0.0 |
GTP HOH |
7.586 6.031 |
O CB |
O6 O |
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| 1o3y | 1 | P84078 | 99.39 | 4e-120 |
X-RAY |
2003-05-20 | ALA | A:110 | A:125 | 0.0 | 0.0 | E | -84.5 | 88.3 | 0.0 | 0.0 | 0.0 |
GTP HOH |
7.193 6.430 |
O CB |
O6 O |
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| ALA | B:110 | B:125 | 0.0 | 0.0 | E | -87.2 | 90.4 | NA | NA | NA | |||||||||||||
| 2j59 | 1 | P84078 | 99.39 | 4e-120 |
X-RAY |
2007-02-20 | ALA | A:110 | A:125 | 0.0 | 0.0 | E | -88.4 | 86.6 | 0.0 | 0.0 | 0.0 |
GTP DIO HOH |
7.181 9.296 5.998 |
O CB O |
O6 C2' O |
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| ALA | B:110 | B:125 | 0.0 | 0.0 | E | -84.4 | 88.2 | NA | NA | NA | |||||||||||||
| ALA | C:110 | C:125 | 0.0 | 0.0 | E | -85.7 | 87.6 | NA | NA | NA | |||||||||||||
| ALA | D:110 | D:125 | 0.0 | 0.0 | E | -84.8 | 87.0 | NA | NA | NA | |||||||||||||
| ALA | E:110 | E:125 | 0.0 | 0.0 | E | -86.4 | 90.5 | NA | NA | NA | |||||||||||||
| ALA | F:110 | F:125 | 0.0 | 0.0 | E | -83.6 | 89.8 | NA | NA | NA | |||||||||||||
| 6ii6 | 2 | P61204 | 98.18 | 1e-119 |
X-RAY |
2019-08-07 | ALA | C:113 | C:125 | 0.0 | 0.0 | E | -83.1 | 87.2 | 0.0 | 0.0 | 0.0 |
GTP HOH |
7.126 6.291 |
O CB |
O6 O |
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| ALA | D:113 | D:125 | 0.0 | 0.0 | E | -85.3 | 92.7 | NA | NA | NA | |||||||||||||
| 3aq4 | 1 | P36397 | 88.33 | 1e-116 |
X-RAY |
2011-01-26 | ALA | A:128 | A:125 | 0.0 | 0.0 | E | -89.6 | 91.4 | 0.0 | 0.0 | 0.0 |
GDP HOH |
6.929 6.217 |
O CB |
O6 O |
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| ALA | B:128 | B:125 | 0.0 | 0.0 | E | -85.3 | 91.1 | NA | NA | NA | |||||||||||||
| 5uf8 | 1 | Q5AND9 | 85.08 | 1e-114 |
X-RAY |
2017-01-25 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -85.3 | 88.5 | 0.0 | 0.0 | 0.0 |
GDP HOH |
6.940 8.122 |
O CB |
O6 O |
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| ALA | B:125 | B:125 | 0.0 | 0.0 | E | -82.2 | 87.0 | NA | NA | NA | |||||||||||||
| ALA | C:125 | C:125 | 0.0 | 0.0 | E | -80.4 | 86.8 | NA | NA | NA | |||||||||||||
| ALA | D:125 | D:125 | 0.0 | 0.0 | E | -77.7 | 86.1 | NA | NA | NA | |||||||||||||
| 6pta | 1 | P22274 | 84.18 | 4e-112 |
X-RAY |
2019-07-24 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -78.8 | 79.7 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.044 6.638 |
O O |
O6 O |
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| ALA | B:125 | B:125 | 0.0 | 0.0 | E | -78.0 | 78.9 | NA | NA | NA | |||||||||||||
| ALA | C:125 | C:125 | 0.0 | 0.0 | E | -75.7 | 89.7 | 0.0 | 0.0 | 0.0 |
GDP HOH |
7.016 6.969 |
O CB |
O6 O |
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| ALA | D:125 | D:125 | 0.0 | 0.0 | E | -78.6 | 89.9 | NA | NA | NA | |||||||||||||
| 1z6x | 1 | P18085 | 81.92 | 2e-108 |
X-RAY |
2005-04-12 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -80.1 | 91.1 | 0.0 | 0.0 | 0.0 |
GDP HOH |
6.895 6.255 |
O O |
O6 O |
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| ALA | B:125 | B:125 | 0.0 | 0.0 | E | -93.9 | 82.9 | NA | NA | NA | |||||||||||||
| 2b6h | 1 | P84085 | 83.14 | 9e-107 |
X-RAY |
2005-10-11 | ALA | A:137 | A:125 | 0.0 | 0.0 | E | -85.3 | 88.7 | 0.0 | 0.0 | 0.0 |
GDP UNX UNX HOH |
6.934 8.837 9.106 8.090 |
O CA CA CB |
O6 UNK UNK O |
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| 4ylg | 1 | C4LXL1 | 80.12 | 6e-102 |
X-RAY |
2015-05-20 | ALA | A:121 | A:121 | 0.0 | 0.0 | E | -87.1 | 92.0 | 0.0 | 0.0 | 0.0 |
GDP HOH |
6.892 3.732 |
O CB |
O6 O |
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| ALA | B:121 | B:121 | 1.0 | 0.009 | E | -85.3 | 87.2 | 1.0 | 0.009 | 0.0 |
GDP HOH |
7.051 3.923 |
O O |
O6 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p84077-f1 | 1 | P84077 | 100.0 | 4e-135 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -78.0 | 80.1 | |
| af-p61204-f1 | 1 | P61204 | 96.13 | 2e-130 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -78.5 | 82.7 | |
| af-p18085-f1 | 1 | P18085 | 81.92 | 1e-108 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -78.3 | 85.4 | |
| af-p84085-f1 | 1 | P84085 | 81.92 | 1e-108 | ALA | A:125 | A:125 | 0.0 | 0.0 | E | -77.2 | 84.0 | |