Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 27948108 . G A CCDS305.1:NM_001042729.1:c.390agC>agT_NP_001036194.1:p.130S>S Homo sapiens FGR proto-oncogene, Src family tyrosine kinase (FGR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3uf4 1 P39688 81.71 2e-94 X-RAY
 2011-12-07 SER A:55 A:135 26.0 0.226 G -62.7 -31.8 26.0 0.226 0.0 GOL
HOH
 7.902
2.639
 C
O
 O1
O
7jt9 1 P09769 96.88 8e-38 X-RAY
 2022-01-26 SER A:55 A:144 25.0 0.217 G -64.9 -27.7 25.0 0.217 0.0 HOH
 2.741
 O
 O
3ua6 1 P06241 82.54 8e-31 X-RAY
 2012-07-25 SER A:56 A:135 21.0 0.183 G -69.2 -20.4 21.0 0.183 0.0 GOL
NA
HOH
 7.000
2.754
3.375
 N
O
O
 O2
NA
O
SER B:56 B:135 25.0 0.217 G -68.0 -22.7 NA NA NA
3ua7 1 P06241 82.54 8e-31 X-RAY
 2012-07-25 SER A:56 A:135 25.0 0.217 G -64.6 -24.2 23.0 0.2 0.017 E:Q9YKI6:0.017
 GOL
HOH
 9.064
2.304
 N
O
 C3
O
SER B:56 B:135 24.0 0.209 G -58.9 -29.6 NA NA NA
SER C:56 C:135 27.0 0.235 G -64.4 -17.9 NA NA NA
SER D:56 D:135 28.0 0.243 G -73.8 -15.3 NA NA NA
4eik 1 P06241 82.54 8e-31 X-RAY
 2013-04-10 SER A:56 A:135 27.0 0.235 G -67.8 -19.0 22.0 0.191 0.044 B:None:0.043
 NA
HOH
 2.332
2.718
 O
OG
 NA
O
7a2v 1 P06241 85.0 2e-30 X-RAY
 2021-08-25 SER A:53 A:135 15.0 0.13 G -65.8 -21.6 15.0 0.13 0.0 HOH
 2.687
 O
 O
7a2u 1 P06241 85.0 3e-30 X-RAY
 2021-08-25 SER A:53 A:135 16.0 0.139 G -61.8 -29.3 16.0 0.139 0.0 HOH
 2.758
 O
 O
6ipy 1 P06241 82.26 3e-30 X-RAY
 2018-11-28 SER A:64 A:135 26.0 0.226 G -65.1 -26.6 26.0 0.226 0.0 HOH
 6.527
 HB3
 O
1fyn 1 P06241 82.26 3e-30 X-RAY
 1996-11-08 SER A:55 A:135 27.0 0.235 G -70.4 -25.1 27.0 0.235 0.0 HOH
 5.639
 CB
 O
1m27 3 P06241 83.61 6e-30 X-RAY
 2003-05-06 SER C:52 C:135 26.0 0.226 G -47.6 -47.7 26.0 0.226 0.0 HOH
 3.025
 N
 O
7a2l 1 P06241 83.33 1e-29 X-RAY
 2021-08-25 SER A:53 A:135 24.0 0.209 G -66.8 -19.7 24.0 0.209 0.0 NA
FMT
HOH
 2.652
6.819
2.771
 O
H
HG
 NA
O2
O
SER B:53 B:135 7.0 0.061 G -66.9 -31.4 NA NA NA
7a2p 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 SER A:53 A:135 20.0 0.174 G -67.4 -23.3 20.0 0.174 0.0 PGE
HOH
 8.402
2.870
 HB2
O
 H2
O
7a2q 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 SER A:53 A:135 18.0 0.157 G -67.4 -23.4 18.0 0.157 0.0 PG4
HOH
 8.471
2.840
 HB2
O
 H51
O
7a2t 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 SER A:53 A:135 23.0 0.2 G -63.3 -24.9 23.0 0.2 0.0 ACT
HOH
 8.197
2.099
 H
HG
 H3
O
7d7s 2 E5RFS5 82.26 1e-29 X-RAY
 2020-11-18 SER C:55 C:135 22.0 0.191 G -56.0 -36.9 NA NA NA
SER D:55 D:135 23.0 0.2 G -55.5 -37.5 21.0 0.183 0.017 A:P03407:0.017
7a2r 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 SER A:54 A:135 22.0 0.191 G -67.4 -22.3 22.0 0.191 0.0 HOH
 2.567
 HG
 O
7a2s 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 SER A:54 A:135 21.0 0.183 G -64.9 -24.5 21.0 0.183 0.0 HOH
 2.176
 HG
 O
7a2j 1 P06241 83.33 2e-29 X-RAY
 2021-08-25 SER A:53 A:135 22.0 0.191 G -67.7 -19.6 22.0 0.191 0.0 NA
HOH
 2.614
3.566
 O
HG
 NA
O
SER B:53 B:135 17.0 0.148 G -63.0 -34.7 NA NA NA
7a2k 1 P06241 83.33 2e-29 X-RAY
 2021-08-25 SER A:53 A:135 23.0 0.2 G -64.3 -23.9 23.0 0.2 0.0 NA
HOH
 2.533
3.325
 O
O
 NA
O
SER B:53 B:135 22.0 0.191 G -63.8 -24.5 NA NA NA
SER C:53 C:135 17.0 0.148 G -63.2 -27.8 NA NA NA
SER D:53 D:135 18.0 0.157 G -63.6 -28.3 NA NA NA
6ipz 1 P06241 82.26 2e-29 X-RAY
 2018-11-28 SER A:61 Z:135 27.0 0.235 G -63.4 -23.2 27.0 0.235 0.0 O4B
HOH
 7.511
8.860
 H
O
 HAG1
O
7a2o 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 SER A:53 A:135 20.0 0.174 G -65.7 -24.0 20.0 0.174 0.0 PGE
HOH
 8.340
2.867
 HB2
O
 H42
O
7a2x 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 SER A:53 A:135 32.0 0.278 G -64.8 -23.5 26.0 0.226 0.052 B:None:0.052
 HOH
 2.316
 HG
 O
7a2y 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 SER A:53 A:135 33.0 0.287 G -64.3 -23.1 26.0 0.226 0.061 B:None:0.061
 HOH
 2.822
 O
 O
7a2z 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 SER A:53 A:135 31.0 0.27 G -64.0 -24.6 25.0 0.217 0.053 B:None:0.052
 HOH
 2.834
 OG
 O
7a2w 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 SER A:54 A:135 32.0 0.278 G -65.3 -22.0 26.0 0.226 0.052 B:None:0.052
 HOH
 2.719
 O
 O
1shf 1 P06241 83.05 1e-28 X-RAY
 1993-10-31 SER A:52 A:135 24.0 0.209 G -66.4 -16.7 24.0 0.209 0.0
SER B:52 B:135 23.0 0.2 G -68.2 -19.1 23.0 0.2 0.0
4znx 1 P06241 82.76 6e-28 X-RAY
 2016-06-29 SER A:52 A:135 27.0 0.235 T -74.2 2.5 0.0 0.0 0.235 F:None:0.235
 HOH
 2.723
 OG
 O
SER B:52 B:135 27.0 0.235 T -72.9 2.3 0.0 0.0 0.235 G:None:0.235
F:None:0.009
 HOH
 1.988
 HG
 O
SER C:52 C:135 29.0 0.252 T -74.9 3.5 0.0 0.0 0.252 G:None:0.009
H:None:0.252
 HOH
 1.793
 HG
 O
SER D:52 D:135 25.0 0.217 T -75.0 2.3 0.0 0.0 0.217 E:None:0.209
H:None:0.009
 HOH
 2.819
 OG
 O
1avz 2 P06241 82.46 2e-27 X-RAY
 1998-03-25 SER C:51 C:135 19.0 0.165 G -47.2 -30.3 19.0 0.165 0.0
5zau 1 P06241 82.46 2e-27 NMR
 2019-09-11 SER A:51 A:135 40.0 0.348 T -63.9 -19.6 21.0 0.183 0.165 B:None:0.165
1efn 1 P06241 81.03 6e-27 X-RAY
 1997-01-11 SER A:51 A:135 21.0 0.183 G -50.4 -38.5 18.0 0.157 0.026 B:P03406:0.026
 HOH
 6.246
 OG
 O
SER C:51 C:135 17.0 0.148 G -46.8 -33.3 15.0 0.13 0.018 D:P03406:0.017
 HOH
 4.982
 OG
 O
4d8d 1 P06241 81.03 7e-27 X-RAY
 2013-01-16 SER A:52 A:135 19.0 0.165 G -52.2 -32.6 17.0 0.148 0.017 B:P03406:0.017
SER C:52 C:135 17.0 0.148 G -57.8 -26.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09769-f1 1 P09769 100.0 0.0 SER A:130 A:130 10.0 0.087 G -59.7 -31.6