Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 27949553 . G A CCDS305.1:NM_001042729.1:c.329aCt>aTt_NP_001036194.1:p.110T>I Homo sapiens FGR proto-oncogene, Src family tyrosine kinase (FGR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3uf4 1 P39688 81.71 2e-94 X-RAY
 2011-12-07 SER A:35 A:115 94.0 0.817 S -104.5 -3.8 94.0 0.817 0.0 HOH
 3.038
 OG
 O
7jt9 1 P09769 96.88 8e-38 X-RAY
 2022-01-26 THR A:35 A:124 112.0 0.8 T -69.4 -26.4 112.0 0.8 0.0 HOH
 3.503
 N
 O
3ua6 1 P06241 82.54 8e-31 X-RAY
 2012-07-25 SER A:36 A:115 114.0 0.991 S -93.7 -2.6 114.0 0.991 0.0 HOH
 2.620
 OG
 O
SER B:36 B:115 99.0 0.861 -107.5 -96.6 NA NA NA
3ua7 1 P06241 82.54 8e-31 X-RAY
 2012-07-25 SER A:36 A:115 107.0 0.93 S -93.6 -20.9 107.0 0.93 0.0 HOH
 3.223
 N
 O
SER B:36 B:115 105.0 0.913 S -95.0 -14.8 NA NA NA
SER C:36 C:115 108.0 0.939 -101.8 3.0 NA NA NA
SER D:36 D:115 99.0 0.861 T -82.5 -2.7 NA NA NA
4eik 1 P06241 82.54 8e-31 X-RAY
 2013-04-10 SER A:36 A:115 96.0 0.835 S -90.3 -19.0 96.0 0.835 0.0 HOH
 3.485
 N
 O
7a2v 1 P06241 85.0 2e-30 X-RAY
 2021-08-25 THR A:33 A:115 108.0 0.771 S -109.9 -3.9 108.0 0.771 0.0 HOH
 3.049
 H
 O
7a2u 1 P06241 85.0 3e-30 X-RAY
 2021-08-25 THR A:33 A:115 112.0 0.8 S -110.7 12.1 112.0 0.8 0.0 HOH
 3.441
 N
 O
6ipy 1 P06241 82.26 3e-30 X-RAY
 2018-11-28 SER A:44 A:115 89.0 0.774 -112.1 32.4 89.0 0.774 0.0 HOH
 3.079
 N
 O
1fyn 1 P06241 82.26 3e-30 X-RAY
 1996-11-08 SER A:35 A:115 102.0 0.887 T -79.9 -9.3 102.0 0.887 0.0 HOH
 3.449
 N
 O
1m27 3 P06241 83.61 6e-30 X-RAY
 2003-05-06 SER C:32 C:115 105.0 0.913 -65.9 -49.3 105.0 0.913 0.0 HOH
 3.140
 N
 O
7a2l 1 P06241 83.33 1e-29 X-RAY
 2021-08-25 SER A:33 A:115 97.0 NA T -76.6 -1.4 97.0 NA NA HOH
 3.606
 HA
 O
SER B:33 B:115 63.0 NA -93.2 171.5 NA NA NA
7a2p 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 THR A:33 A:115 108.0 0.771 S -108.7 15.4 108.0 0.771 0.0 PGE
HOH
 4.791
2.403
 HG23
HG23
 H1
O
7a2q 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 THR A:33 A:115 118.0 0.843 S -105.3 13.8 118.0 0.843 0.0 PG4
HOH
 5.071
2.789
 HG22
HG22
 H71
O
7a2t 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 THR A:33 A:115 112.0 0.8 S -104.3 8.6 112.0 0.8 0.0 ACT
HOH
 9.811
1.931
 C
HG1
 H3
O
7d7s 2 E5RFS5 82.26 1e-29 X-RAY
 2020-11-18 SER C:35 C:115 77.0 0.67 S -70.4 161.5 NA NA NA
SER D:35 D:115 105.0 0.913 S -67.6 -60.4 105.0 0.913 0.0
7a2r 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 THR A:34 A:115 115.0 0.821 S -109.5 13.0 115.0 0.821 0.0 HOH
 2.050
 HG1
 O
7a2s 1 P06241 81.97 1e-29 X-RAY
 2021-08-25 THR A:34 A:115 114.0 0.814 S -107.1 12.0 114.0 0.814 0.0 HOH
 2.771
 HG1
 O
7a2j 1 P06241 83.33 2e-29 X-RAY
 2021-08-25 SER A:33 A:115 114.0 0.991 S -100.6 11.8 114.0 0.991 0.0 HOH
 3.007
 HA
 O
SER B:33 B:115 61.0 NA -129.7 179.3 NA NA NA
7a2k 1 P06241 83.33 2e-29 X-RAY
 2021-08-25 SER A:33 A:115 110.0 0.957 S -122.2 21.9 110.0 0.957 0.0 HOH
 2.981
 HA
 O
SER B:33 B:115 114.0 0.991 T -94.8 14.5 NA NA NA
SER C:33 C:115 61.0 NA -127.0 -179.9 NA NA NA
SER D:33 D:115 75.0 NA -118.8 21.3 NA NA NA
6ipz 1 P06241 82.26 2e-29 X-RAY
 2018-11-28 SER A:41 Z:115 102.0 0.887 T -60.7 -23.8 102.0 0.887 0.0 O4B
 8.082
 HG
 HAK1
7a2o 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 THR A:33 A:115 117.0 0.836 S -103.0 21.0 117.0 0.836 0.0 PGE
HOH
 5.246
2.921
 HG23
HA
 H62
O
7a2x 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 THR A:33 A:115 110.0 0.786 S -104.2 -14.4 110.0 0.786 0.0 HOH
 2.517
 HG1
 O
7a2y 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 THR A:33 A:115 109.0 0.779 S -103.0 -12.8 109.0 0.779 0.0 HOH
 2.545
 HG1
 O
7a2z 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 THR A:33 A:115 112.0 0.8 S -107.5 -10.8 112.0 0.8 0.0 HOH
 2.918
 HA
 O
7a2w 1 P06241 81.67 5e-29 X-RAY
 2021-08-25 THR A:34 A:115 108.0 0.771 S -100.5 -4.0 108.0 0.771 0.0 HOH
 2.214
 HG1
 O
1shf 1 P06241 83.05 1e-28 X-RAY
 1993-10-31 SER A:32 A:115 111.0 0.965 S -112.5 2.5 59.0 0.513 0.452 A:P06241:0.452
SER B:32 B:115 49.0 0.426 -88.9 178.1 49.0 0.426 0.0
4znx 1 P06241 82.76 6e-28 X-RAY
 2016-06-29 SER A:32 A:115 102.0 0.887 -94.5 -2.9 73.0 0.635 0.252 F:None:0.252
 HOH
 3.378
 H
 O
SER B:32 B:115 101.0 0.878 S -95.3 -0.8 101.0 0.878 0.0 HOH
 3.294
 H
 O
SER C:32 C:115 104.0 0.904 S -96.9 -0.6 104.0 0.904 0.0 HOH
 3.317
 H
 O
SER D:32 D:115 103.0 0.896 S -97.1 -2.0 77.0 0.67 0.226 E:None:0.226
 HOH
 3.552
 H
 O
1avz 2 P06241 82.46 2e-27 X-RAY
 1998-03-25 SER C:31 C:115 107.0 0.93 T -67.7 67.6 107.0 0.93 0.0
5zau 1 P06241 82.46 2e-27 NMR
 2019-09-11 SER A:31 A:115 106.0 0.922 T -91.6 10.6 105.0 0.913 0.009 B:None:0.009
1efn 1 P06241 81.03 6e-27 X-RAY
 1997-01-11 SER A:31 A:115 97.0 NA S -98.6 3.7 97.0 NA NA HOH
 7.279
 C
 O
SER C:31 C:115 108.0 0.939 S -96.1 -14.9 108.0 0.939 0.0 HOH
 3.134
 O
 O
4d8d 1 P06241 81.03 7e-27 X-RAY
 2013-01-16 SER A:32 A:115 97.0 0.843 T -83.7 -25.7 97.0 0.843 0.0
SER C:32 C:115 109.0 0.948 S -102.0 14.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09769-f1 1 P09769 100.0 0.0 THR A:110 A:110 105.0 0.75 S -68.6 -27.2