Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 55524219 . A C CCDS603.1:NM_174936.3:c.1402Aca>Cca_NP_777596.2:p.468T>P Homo sapiens proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p4e 1 Q8NBP7 99.71 0.0 X-RAY
 2007-04-10 THR A:468 NA:NA DO NA DO DO DO NA NA NA
THR B:468 A:468 93.0 0.664 -55.8 144.3 NA NA NA
6u2f 1 Q8NBP7 99.71 0.0 X-RAY
 2020-02-05 THR A:468 A:468 100.0 0.714 S -52.4 143.4 100.0 0.714 0.0
5vlp 1 Q8NBP7 99.71 0.0 X-RAY
 2017-08-16 THR A:468 A:468 92.0 0.657 S -53.2 137.9 92.0 0.657 0.0
6u3i 1 Q8NBP7 99.71 0.0 X-RAY
 2020-02-05 THR A:468 A:468 100.0 0.714 S -56.6 138.2 100.0 0.714 0.0
6u26 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 THR A:438 NA:NA DO NA DO DO DO NA NA NA
THR B:438 B:468 96.0 0.686 -56.0 145.8 NA NA NA
6u2n 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 THR A:438 NA:NA DO NA DO DO DO NA NA NA
THR B:438 B:468 115.0 0.821 -26.8 360.0 115.0 0.821 0.0 HOH
 4.412
 O
 O
6u2p 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 THR A:438 NA:NA DO NA DO DO DO NA NA NA
THR B:438 B:468 65.0 0.464 -34.3 134.5 65.0 0.464 0.0
6u36 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 THR A:438 NA:NA DO NA DO DO DO NA NA NA
THR B:438 B:468 89.0 0.636 -170.2 137.5 89.0 0.636 0.0
6u38 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 THR A:438 NA:NA DO NA DO DO DO NA NA NA
THR B:438 B:468 92.0 0.657 -63.3 135.7 92.0 0.657 0.0
6u3x 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 THR A:438 NA:NA DO NA DO DO DO NA NA NA
THR B:438 B:468 71.0 0.507 -90.6 134.9 71.0 0.507 0.0
2pmw 2 Q5SZQ2 100.0 0.0 X-RAY
 2007-05-08 THR B:316 B:468 92.0 0.657 -52.4 151.6 92.0 0.657 0.0 HOH
 2.696
 OG1
 O
3p5b 2 Q8NBP7 99.81 0.0 X-RAY
 2011-10-26 THR B:316 A:468 84.0 0.6 S -63.8 157.8 84.0 0.6 0.0
3p5c 2 Q8NBP7 99.81 0.0 X-RAY
 2011-10-26 THR B:316 A:468 83.0 0.593 S -63.7 157.8 83.0 0.593 0.0
3bps 2 Q8NBP7 99.63 0.0 X-RAY
 2008-02-12 THR B:316 A:468 104.0 0.743 S -47.2 157.5 104.0 0.743 0.0 HOH
 6.047
 C
 O
3gcw 2 Q8NBP7 99.63 0.0 X-RAY
 2009-03-03 THR B:316 A:468 98.0 0.7 S -49.4 147.3 98.0 0.7 0.0
3gcx 2 Q8NBP7 99.63 0.0 X-RAY
 2009-03-03 THR B:316 A:468 99.0 0.707 S -52.9 152.7 99.0 0.707 0.0
3sqo 1 Q8NBP7 99.63 0.0 X-RAY
 2012-05-16 THR A:316 A:468 84.0 0.6 S -77.7 177.9 84.0 0.6 0.0 HOH
 2.823
 CG2
 O
4ne9 1 Q8NBP7 99.63 0.0 X-RAY
 2014-09-10 THR A:316 A:468 99.0 0.707 -49.8 141.9 99.0 0.707 0.0
THR B:316 B:468 99.0 0.707 -49.2 141.3 NA NA NA
4k8r 2 Q8NBP7 99.63 0.0 X-RAY
 2013-05-08 THR B:316 B:468 91.0 0.65 -60.5 157.2 91.0 0.65 0.0 HOH
 6.864
 OG1
 O
5vl7 2 Q8NBP7 99.63 0.0 X-RAY
 2017-08-16 THR B:316 NA:NA DO NA DO DO DO NA NA NA
2qtw 2 Q8NBP7 99.63 0.0 X-RAY
 2007-09-18 THR B:316 B:468 91.0 0.65 -57.6 141.4 91.0 0.65 0.0 HOH
 2.908
 OG1
 O
7kev 2 Q8NBP7 99.63 0.0 X-RAY
 2021-11-24 THR B:316 B:468 68.0 0.486 S -70.5 162.4 68.0 0.486 0.0
7kfa 2 Q8NBP7 99.63 0.0 X-RAY
 2021-11-10 THR B:316 B:468 90.0 0.643 -64.8 148.9 90.0 0.643 0.0
3m0c 2 Q8NBP7 99.44 0.0 X-RAY
 2011-03-16 THR B:316 B:468 91.0 0.65 -57.5 141.4 91.0 0.65 0.0
3h42 2 Q8NBP7 99.26 0.0 X-RAY
 2009-05-05 THR B:316 B:468 92.0 0.657 -49.3 149.7 92.0 0.657 0.0
5oca 2 Q8NBP7 99.26 0.0 X-RAY
 2017-09-20 THR B:316 B:468 101.0 0.721 -66.6 139.1 101.0 0.721 0.0 HOH
 6.439
 CB
 O
7anq 1 Q8NBP7 100.0 6e-167 X-RAY
 2021-10-20 THR A:17 A:468 83.0 0.593 S -102.9 170.0 83.0 0.593 0.0 HOH
 3.866
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8nbp7-f1 1 Q8NBP7 100.0 0.0 THR A:468 A:468 94.0 0.671 S -70.2 144.3